Fungal myocarditis
Open accessAbstract
The incidence of invasive fungal disease has dramatically increased over the past few decades corresponding to the rising number of immunocompromised patients. The major risk factors for severe fungal disease include administration of broad-spectrum antibiotics, corticosteroids and cytotoxic agents, invasive medical procedures, and Human Immunodeficiency Virus (HIV) infection. Invasive fungal infections often affect multiple organs, and involvement of the myocardium frequently occurs in disseminated disease. Premortem diagnosis of fungal myocarditis is difficult since clinical findings of myocardial involvement are often absent or ambiguous and blood cultures are often negative. The major fungal pathogens responsible for myocardial infection and the clinical settings in which they occur are reviewed.
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Candidal myocarditis is usually part of the syndrome of disseminated candidiasis, is clinically silent, and is treated as part of the therapy of disseminated disease.
“Candidal myocarditis is usually part of the syndrome of disseminated candidiasis, is clinically silent, and is treated as part of the therapy of disseminated disease [224].”
From Guidelines for Treatment of Candidiasis (2004) · cites this paper as [224]
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Guidelines for Treatment of Candidiasis
Pappas, P. G., Rex, J. H., Sobel, J. D., Filler, S. G., Dismukes, W. E., Walsh, T. J., & Edwards, J. E. (2004) · Clinical Infectious Diseases · doi:10.1086/380796 · Cited by 1,440 · see citing works
Cardiac Apoptosis in Severe Relapsing Fever Borreliosis
Londoño, D., Bai, Y., Zückert, W. R., et al. (2005) · Infection and Immunity · doi:10.1128/iai.73.11.7669-7676.2005 · Cited by 27 · see citing works
Infectious factors in myocarditis: a comprehensive review of common and rare pathogens
Yao, Z., Liang, M., & Zhu, S. (2024) · The Egyptian Heart Journal · doi:10.1186/s43044-024-00493-3 · Cited by 13 · see citing works
Sasikumar, J., Ebrahim, R. A., & Das, S. P. (2025) · Mycoses · doi:10.1111/myc.70014 · Cited by 11 · see citing works
Barros, K. L., Tepper, J. W., Ramchandani, J., et al. (2023) · Pediatric Transplantation · doi:10.1111/petr.14585 · Cited by 2 · see citing works
Nosanchuk, J., & Deepe, G. (2006) · ASM Press eBooks · doi:10.1128/9781555815776.ch38 · Cited by 1 · see citing works
Self-citationOBSOLETE: Chronic Infections of the Heart
Edwards, M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.99719-8
Chronic Infections of the Heart
Edwards, M., Withers, C., & Thakarar, K. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809657-4.99719-9
Rücklová, K., David, J., Koubský, K., Pavlíček, J., Klásková, E., Šedivý, V., Krupičková, S., Malcová, H., Komínová, J., Vít, P., et al. (2023) · Cor et Vasa · doi:10.33678/cor.2022.096
- Authors
- Nosanchuk, J. D.
- Affiliations
- Albert Einstein College of Medicine (US)
- Corresponding author
- Nosanchuk, Joshua Daniel
- Venue
- Frontiers in bioscience
- Publisher
- IMR Press
- Published
- 2002
- Volume
- 7
- Issue
- 4
- Pages
- d1423-1438
- ISSN
- 1093-4715 (ISSN-L)
- 1093-9946
- DOI
- 10.2741/a850
- OpenAlex
- W4206690961
- Cited by
- 16
- References
- 0
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 2 · 2020: 1 · 2017: 2 · 2014: 2 · 2013: 1
- FWCI
- 0.51
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Frontiers in bioscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases (K08AI001489, AI-01489)
- Topics
- Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Epidemiology › Infective Endocarditis Diagnosis and Management
- Keywords
- invasive fungal infections, immunocompromised patients, fungal pathogens, disseminated fungal infection, risk factors, antifungal agents, HIV infection, corticosteroids, cytotoxic drugs, broad-spectrum antibiotics
- MeSH terms
- Antifungal Agents, Humans, Mycoses, Myocarditis, Surgical Wound Infection, Immunocompromised Host, AIDS-Related Opportunistic Infections
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