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Antibodies and Antimatter: The Resurgence of Immuno-PET
Open accessAbstract
The completion of the human genome, coupled with parallel major research efforts in proteomics and systems biology, has led to a flood of information on the roles of individual genes and proteins in normal physiologic processes and their disruptions in disease. In practical terms, this information has opened the door to increasingly targeted therapies as specific molecular markers are identified and validated. The ongoing transition from empiric to molecular medicine has engendered a need for corresponding molecular diagnostics, including noninvasive molecular imaging. Convergence of knowledge regarding key biomarkers that define normal biologic processes and disease with protein and imaging technology makes this an opportune time to revisit the combination of antibodies and PET, or immuno-PET.
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An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy
Tavaré, R., Escuin-Ordinas, H., Mok, S., McCracken, M. N., Zettlitz, K. A., Salazar, F. B., Witte, O. N., Ribas, A., & Wu, A. M. (2016) · Cancer Research · doi:10.1158/0008-5472.can-15-1707 · Cited by 320
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Metadata
- Authors
- Wu, A. M.
- Venue
- Journal of Nuclear Medicine
- Publisher
- Society of Nuclear Medicine
- Published
- 2008-12-17
- Volume
- 50
- Issue
- 1
- Pages
- 2-5
- ISSN
- 0161-5505 (ISSN-L)
- 2159-662X
- OpenAlex
- W2153750906
- Cited by
- 184
- References
- 0
- FWCI
- 9.80
- Type
- journal article
- Language
- en
- Open access
- bronze
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