The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Tumor pH and Its Measurement
Open accessAbstract
Studies over the last few decades have demonstrated that the intracellular pH of solid tumors is maintained within a range of 7.0-7.2, whereas the extracellular pH is acidic. A low extracellular pH may be an important factor inducing more aggressive cancer phenotypes. Research into the causes and consequences of this acidic pH of tumors is highly dependent on accurate, precise, and reproducible measurements, and these have undergone great changes in the last decade. This review focuses on the most recent advances in the in vivo measurement of tumor pH by pH-sensitive PET radiotracers, MR spectroscopy, MRI, and optical imaging.
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Citations
Cites
Why Do Cancers Have High Aerobic Glycolysis?
Gatenby, R. A., & Gillies, R. J. (2004) · Nature reviews. Cancer · doi:10.1038/nrc1478 · Cited by 4,784
Cited by
Optical Sensing and Imaging of pH Values: Spectroscopies, Materials, and Applications
Steinegger, A., Wolfbeis, O. S., & Borisov, S. M. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00451 · Cited by 622
The acidic tumor microenvironment: a target for smart cancer nano-theranostics
Feng, L., Dong, Z., Tao, D., Zhang, Y., & Liu, Z. (2018) · National Science Review · doi:10.1093/nsr/nwx062 · Cited by 426
Zhou, K., Liu, H., Zhang, S., Huang, X., Wang, Y., Huang, G., Sumer, B. D., & Gao, J. (2012) · Journal of the American Chemical Society · doi:10.1021/ja300176w · Cited by 344
Manipulating extracellular tumour pH: an effective target for cancer therapy
Hao, G., Xu, Z. P., & Li, L. (2018) · RSC Advances · doi:10.1039/c8ra02095g · Cited by 341
Natural D ‐glucose as a biodegradable MRI contrast agent for detecting cancer
Chan, K. W. Y., McMahon, M. T., Kato, Y., Liu, G., Bulte, J. W. M., Bhujwalla, Z. M., Artemov, D., & van Zijl, P. C. M. (2012) · Magnetic Resonance in Medicine · doi:10.1002/mrm.24520 · Cited by 337
Metadata
- Authors
- Zhang, X., Lin, Y., & Gillies, R. J.
- Venue
- Journal of Nuclear Medicine
- Publisher
- Society of Nuclear Medicine
- Published
- 2010-07-21
- Volume
- 51
- Issue
- 8
- Pages
- 1167-1170
- ISSN
- 0161-5505 (ISSN-L)
- 2159-662X
- OpenAlex
- W2051708290
- Cited by
- 659
- References
- 1
- FWCI
- 5.69
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Zhang, X., Lin, Y., & Gillies, R. J. (2010). Tumor pH and Its Measurement. Journal of Nuclear Medicine. https://doi.org/10.2967/jnumed.109.068981
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
