The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Liver Glycogen in Man –- the Effect of Total Starvation or a Carbohydrate-Poor Diet Followed by Carbohydrate Refeeding
Abstract
Liver glycogen content was determined in specimens obtained by repeated percutaneous biopsies during starvation and under various dietary conditions in 19 human subjects. During rest and following an overnight fast, there was a decrease in liver glycogen content by a mean of 0.30 mmol glucosyl units per kg wet liver tissue per min during a further 4 hours' starvation. Prolonged starvation or carbohydrate-poor normocaloric diet decreased the liver glycogen from a mean of 232 to 24–55 mmol glucosyl units per kg within 24 hours. During an additional period of up to 9 days on the carbohydrate-poor diet the liver glycogen remained at a low level. Refeeding with a carbohydrate-rich diet gave a rapid increase of the liver glycogen to supernormal values, 424–624 mmol glucosyl units per kg wet liver tissue.
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“Under a resting postprandial state, the production of blood glucose relies primarily on glycogenolysis [105].”
From Regulation of Energy Substrate Metabolism in Endurance Exercise (2021) · cites this paper as [105]
In the citing paper
“When training fasted, muscle glycogen should be unaffected by the overnight fast, but liver glycogen will be very low [33].”
From Periodized Nutrition for Athletes (2017) · cites this paper as [33]
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Metadata
- Authors
- Nilsson, L. H., & Hultman, E.
- Venue
- Scandinavian Journal of Clinical and Laboratory Investigation
- Publisher
- Informa UK Limited
- Published
- 1973-01
- Volume
- 32
- Issue
- 4
- Pages
- 325-330
- ISSN
- 0036-5513 (ISSN-L)
- 1502-7686
- OpenAlex
- W2008406557
- Cited by
- 263
- References
- 30
- Citations by year
- 2026: 6 · 2025: 11 · 2024: 4 · 2023: 2 · 2022: 6 · 2021: 5 · 2020: 6 · 2019: 4 · 2018: 4 · 2017: 6 · 2016: 5 · 2015: 6 · 2014: 6 · 2013: 10 · 2012: 7
- FWCI
- 1.93
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Scandinavian Journal of Clinical and Laboratory Investigation (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Glycogen Storage Diseases and Myoclonus
- Keywords
- liver glycogen, starvation, carbohydrate refeeding, glycogen depletion, glycogen synthesis, overnight fasting, percutaneous liver biopsy, research participants
- MeSH terms
- Adult, Biopsy, Needle, Blood Glucose, Blood Pressure, Body Weight, Depression, Chemical, Dietary Carbohydrates, Female, Glycogen, Humans, Liver, Male, Middle Aged, Pulse, Starvation, Stimulation, Chemical, Time Factors
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