The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Assessment of the Neutrophil Dominating Protein Calprotectin in Feces: A Methodologic Study
Abstract
This study describes methods for extraction and quantification of calprotectin (L1 protein) in feces by enzyme immunoassay. This protein is a prominent antimicrobial component of neutrophils, monocytes, macrophages, and squamous epithelia. Calprotectin was stable in feces during storage for 7 days at room temperature. Small fecal samples taken from a 24-h feces collection gave a reliable estimate of calprotectin. Within-assay precision was 1.9%, and between-assay precision 14.8%. In healthy subjects (n = 33) median fecal calprotectin was 2025 micrograms/l and in hospital controls (n = 40) 10,500 micrograms/l. Median values in patients with Crohn's disease (n = 21) was 43,000 micrograms/l and in ulcerative colitis (n = 17) 40,000 micrograms/l. Fecal calprotectin was significantly correlated to fecal alpha 1-antitrypsin in the patients with Crohn's disease. Ten of 11 patients with gastrointestinal carcinomas had calprotectin level above the suggested reference limit of 6740 micrograms/l.
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Citations
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Dale, I., Brandtzaeg, P., Fagerhol, M. K., & Scott, H. (1985) · American Journal of Clinical Pathology · doi:10.1093/ajcp/84.1.24 · Cited by 177
Cited by
Tibble, J. A., Sigthorsson, G., Bridger, S., Fagerhol, M. K., & Bjarnason, I. (2000) · Gastroenterology · doi:10.1053/gast.2000.8523 · Cited by 759
Self-citationde Magistris, L., Familiari, V., Pascotto, A., Sapone, A., Frolli, A., Iardino, P., Carteni, M., De Rosa, M., Francavilla, R., Riegler, G., et al. (2010) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e3181dcc4a5 · Cited by 546
Calprotectin: from biomarker to biological function
Jukic, A., Bakiri, L., Wagner, E. F., Tilg, H., & Adolph, T. E. (2021) · Gut · doi:10.1136/gutjnl-2021-324855 · Cited by 500
Abnormal Intestinal Permeability in Subgroups of Diarrhea-Predominant Irritable Bowel Syndromes
Dunlop, S. P., Hebden, J., Campbell, E., Naesdal, J., Olbe, L., Perkins, A. C., & Spiller, R. C. (2006) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2006.00672.x · Cited by 476
Biomarkers in inflammatory bowel disease: current practices and recent advances.
Iskandar, H. N., & Ciorba, M. A. (2012) · Translational Research · doi:10.1016/j.trsl.2012.01.001 · Cited by 210
Metadata
- Authors
- RØseth, A. G., Fagerhol, M. K., Aadland, E., & Schjønsby, H.
- Venue
- Scandinavian Journal of Gastroenterology
- Publisher
- Informa UK Limited
- Published
- 1992-01
- Volume
- 27
- Issue
- 9
- Pages
- 793-798
- ISSN
- 0036-5521 (ISSN-L)
- 1502-7708
- OpenAlex
- W2133955925
- Cited by
- 669
- References
- 1
- FWCI
- 2.32
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Assessment of the Neutrophil Dominating Protein Calprotectin in Feces: A Methodologic Study. https://app.cochat.ai/papers/10.3109/00365529209011186
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- RØseth, A. G., Fagerhol, M. K., Aadland, E., & Schjønsby, H. (1992). Assessment of the Neutrophil Dominating Protein Calprotectin in Feces: A Methodologic Study. Scandinavian Journal of Gastroenterology. https://doi.org/10.3109/00365529209011186
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
