Interleukin-17A antagonist attenuates radiation-induced lung injuries in mice

IL-17 and th17 cells

Korn, T., Bettelli, E., Oukka, M., & Kuchroo, V. K. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132710 · Cited by 4,873 · see citing works

Simple method of estimating severity of pulmonary fibrosis on a numerical scale.

Ashcroft, T., Simpson, J. M., & Timbrell, V. (1988) · Journal of Clinical Pathology · doi:10.1136/jcp.41.4.467 · Cited by 1,692 · see citing works

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines

Fossiez, F., Djossou, O., Chomarat, P., Flores-Romo, L., Ait-Yahia, S., Maat, C., Pin, J. J., Garrone, P., Garcia, E., Saeland, S., et al. (1996) · The Journal of Experimental Medicine · doi:10.1084/jem.183.6.2593 · Cited by 1,526 · cited 1× · see citing works

Targeting IL-17 and TH17 cells in chronic inflammation

Miossec, P., & Kolls, J. K. (2012) · Nature Reviews Drug Discovery · doi:10.1038/nrd3794 · Cited by 1,414 · see citing works

Human IL-17: a novel cytokine derived from T cells

Yao, Z., Painter, S. L., Fanslow, W. C., Ulrich, D., Macduff, B. M., Spriggs, M. K., & Armitage, R. J. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.155.12.5483 · Cited by 1,021 · see citing works

Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent

Wilson, M. S., Madala, S. K., Ramalingam, T. R., Gochuico, B. R., Rosas, I. O., Cheever, A. W., & Wynn, T. A. (2010) · Journal of Experimental Medicine · doi:10.1084/jem.20092121 · Cited by 730 · see citing works

Treatment with a neutralizing anti‐murine interleukin‐17 antibody after the onset of collagen‐induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion

Lubberts, E., Koenders, M. I., Oppers‐Walgreen, B., van den Bersselaar, L., Roo, C. J. J. C., Joosten, L. A. B., & van den Berg, W. B. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20001 · Cited by 709 · see citing works

Interleukin-17 is a negative regulator of established allergic asthma

Schnyder‐Candrian, S., Togbe, D., Couillin, I., Mercier, I., Brombacher, F., Quesniaux, V. F. J., Fossiez, F., Ryffel, B., & Schnyder, B. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20061401 · Cited by 564 · see citing works

Modified assay for determination of hydroxyproline in a tissue hydrolyzate

Edwards, C. A., & O’Brien, W. D. (1980) · Clinica Chimica Acta · doi:10.1016/0009-8981(80)90192-8 · Cited by 477 · see citing works

LY2439821, a humanized anti–interleukin‐17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double‐blind, placebo‐controlled, proof‐of‐concept study

Genovese, M. C., den Bosch, F. E. V., Roberson, S., Bojin, S., Biagini, I. M., Ryan, P. F. J., & Sloan‐Lancaster, J. (2010) · Arthritis & Rheumatism · doi:10.1002/art.27334 · Cited by 449 · see citing works

Blockade of Interleukin-17A Results in Reduced Atherosclerosis in Apolipoprotein E–Deficient Mice

Smith, E. E., Prasad, K.-M. R., Butcher, M. J., Dobrian, A. D., Kolls, J. K., Ley, K. F., & Galkina, E. (2010) · Circulation · doi:10.1161/circulationaha.109.924886 · Cited by 422 · see citing works

Radiation pneumonitis and pulmonary fibrosis in non–small-cell lung cancer: Pulmonary function, prediction, and prevention

Mehta, V. K. (2005) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2005.03.047 · Cited by 416 · see citing works

Blocking IL-17A Promotes the Resolution of Pulmonary Inflammation and Fibrosis Via TGF-β1–Dependent and –Independent Mechanisms

Mi, S., Li, Z., Yang, H.-Z., Liu, H., Wang, J.-P., Ma, Y.-G., Wang, X.-X., Liu, H.-Z., Sun, W., & Hu, Z.-W. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1004081 · Cited by 370 · see citing works

Interleukin-17A Is Dispensable for Myocarditis but Essential for the Progression to Dilated Cardiomyopathy

Baldeviano, G. C., Barin, J. G., Talor, M. V., Srinivasan, S., Bedja, D., Zheng, D., Gabrielson, K., Iwakura, Y., Rose, N. R., & Cihakova, D. (2010) · Circulation Research · doi:10.1161/circresaha.109.213157 · Cited by 334 · see citing works

Inhibition of Integrin αvβ6, an Activator of Latent Transforming Growth Factor-β, Prevents Radiation-induced Lung Fibrosis

Puthawala, K., Hadjiangelis, N., Jacoby, S. C., Bayongan, E., Zhao, Z., Yang, Z., Devitt, M. L., Horan, G. S., Weinreb, P. H., Lukashev, M. E., et al. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200706-806oc · Cited by 272 · see citing works

Radiation pneumonitis and early circulatory cytokine markers

Chen, Y., Williams, J. P., Ding, I., Hernady, E., Liu, W., Smudzin, T., Finkelstein, J. N., Rubin, P., & Okunieff, P. (2002) · Seminars in Radiation Oncology · doi:10.1053/srao.2002.31360 · Cited by 236 · see citing works

NF-κB-mediated adaptive resistance to ionizing radiation

Ahmed, K. M., & Li, J.-J. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.09.022 · Cited by 222 · see citing works

Radiation-Induced Pulmonary Fibrosis: Examination of Chemokine and Chemokine Receptor Families

Johnston, C. J., Williams, J. P., Okunieff, P., et al. (2002) · Radiation Research · doi:10.1667/0033-7587(2002)157[0256:ripfeo]2.0.co;2 · Cited by 176 · see citing works

Stereotactic Body Radiation Therapy for Patients With Lung Cancer Previously Treated With Thoracic Radiation

Kelly, P., Balter, P. A., Rebueno, N. C. S., Sharp, H. J., Liao, Z. X., Komaki, R. U., & Chang, J. Y. (2010) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2009.09.070 · Cited by 175 · see citing works

Circulating IL-6 as a predictor of radiation pneumonitis

Chen, Y., Rubin, P., Williams, J., Hernady, E., Smudzin, T., & Okunieff, P. (2001) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(00)01445-0 · Cited by 165 · see citing works

LY2109761 Attenuates Radiation-Induced Pulmonary Murine Fibrosis via Reversal of TGF-β and BMP-Associated Proinflammatory and Proangiogenic Signals

Flechsig, P., Dadrich, M., Bickelhaupt, S., Jenne, J., Hauser, K., Timke, C., Peschke, P., Hahn, E. W., Gröne, H., Yingling, J. M., et al. (2012) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-11-2855 · Cited by 149 · see citing works

Dietary Curcumin Increases Antioxidant Defenses in Lung, Ameliorates Radiation-Induced Pulmonary Fibrosis, and Improves Survival in Mice

Lee, J. C., Kinniry, P. A., Arguiri, E., et al. (2010) · Radiation Research · doi:10.1667/rr1522.1 · Cited by 148 · see citing works

Early Variations of Circulating Interleukin-6 and Interleukin-10 Levels During Thoracic Radiotherapy Are Predictive for Radiation Pneumonitis

Arpin, D., Pérol, D., Blay, J., Falchero, L., Claude, L., Vuillermoz‐Blas, S., Martel‐Lafay, I., Ginestet, C., Alberti, L., Nosov, D., et al. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.01.7145 · Cited by 146 · see citing works

Targeting the TGF-β1 Pathway to Prevent Normal Tissue Injury After Cancer Therapy

Anscher, M. S. (2010) · The Oncologist · doi:10.1634/theoncologist.2009-s101 · Cited by 140 · see citing works

Cell Adhesion Molecules Regulate Fibrotic Process via Th1/Th2/Th17 Cell Balance in a Bleomycin-Induced Scleroderma Model

Yoshizaki, A., Yanaba, K., Iwata, Y., Komura, K., Ogawa, A., Akiyama, Y., Muroi, E., Hara, T., Ogawa, F., Takenaka, M., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0901778 · Cited by 139 · see citing works

Predicting Risk of Radiation-Induced Lung Injury

Madani, I., Ruyck, K. D., Goeminne, H., et al. (2007) · Journal of Thoracic Oncology · doi:10.1097/jto.0b013e318145b2c6 · Cited by 137 · see citing works

Targeting TLR2 Attenuates Pulmonary Inflammation and Fibrosis by Reversion of Suppressive Immune Microenvironment

Yang, H., Cui, B., Liu, H.-Z., Chen, Z., Yan, H., Hua, F., & Hu, Z. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.182.1.692 · Cited by 103 · see citing works

The bronchiolar epithelium as a prominent source of pro-inflammatory cytokines after lung irradiation

Rübe, C. E., Rübe, C. E., Uthe, D., et al. (2005) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2004.12.072 · Cited by 102 · see citing works

Combining Physical and Biologic Parameters to Predict Radiation-Induced Lung Toxicity in Patients With Non-Small-Cell Lung Cancer Treated With Definitive Radiation Therapy

Stenmark, M. H., Cai, X., Shedden, K., et al. (2012) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2012.03.067 · Cited by 97 · see citing works

Interleukin (IL)-1A and IL-6: Applications to the predictive diagnostic testing of radiation pneumonitis

Chen, Y., Hyrien, O., Williams, J. P., Okunieff, P., Smudzin, T., & Rubin, P. (2005) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2005.01.041 · Cited by 97 · see citing works

Irradiation Induces a Biphasic Expression of Pro-Inflammatory Cytokines in the Lung

Rübe, C. E., Wilfert, F., Palm, J., König, J., Burdak‐Rothkamm, S., Liu, L., Schuck, A., Willich, N., & Rübe, C. (2004) · Strahlentherapie und Onkologie · doi:10.1007/s00066-004-1265-7 · Cited by 95 · see citing works

Pulmonary Lipopolysaccharide (LPS)-Binding Protein Inhibits the LPS-Induced Lung Inflammation In Vivo

Knapp, S., Florquin, S., Golenbock, D. T., & van der Poll, T. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.5.3189 · Cited by 84 · see citing works

Inhibition of the Tumor Necrosis Factor-α Pathway Is Radioprotective for the Lung

Zhang, M., Qian, J. J., Xing, X., et al. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-07-1894 · Cited by 72 · see citing works

Simvastatin Attenuates Radiation-Induced Murine Lung Injury and Dysregulated Lung Gene Expression

Mathew, B., Huang, Y., Jacobson, J. R., Berdyshev, E., Gerhold, L. M., Wang, T., Moreno‐Vinasco, L., Lang, G. D., Zhao, Y., Chen, C. T., et al. (2010) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2010-0122oc · Cited by 68 · see citing works

The TGF-β1 dynamics during radiation therapy and its correlation to symptomatic radiation pneumonitis in lung cancer patients

Kim, J.-Y., Kim, Y., Kim, Y., et al. (2009) · Radiation Oncology · doi:10.1186/1748-717x-4-59 · Cited by 53 · see citing works

Radiation-induced changes in breathing frequency and lung histology of C57BL/6J mice are time- and dose-dependent

Eldh, T., Heinzelmann, F., Velalakan, A., et al. (2012) · Strahlentherapie und Onkologie · doi:10.1007/s00066-011-0046-3 · Cited by 49 · see citing works

Distinct Loci Influence Radiation-Induced Alveolitis from Fibrosing Alveolitis in the Mouse

Haston, C. K., Begin, M., Dorion, G., et al. (2007) · Cancer Research · doi:10.1158/0008-5472.can-07-2733 · Cited by 48 · see citing works

Cellular Inflammatory Infiltrate in Pneumonitis Induced by a Single Moderate Dose of Thoracic X Radiation in Rats

Szabo, S., Ghosh, S. N., Fish, B. L., et al. (2010) · Radiation Research · doi:10.1667/rr1753.1 · Cited by 43 · see citing works

Mechanisms and Potential Targets for Prevention and Treatment of Normal Tissue Injury After Radiation Therapy

Anscher, M. S., & Vujašković, Ž. (2005) · Seminars in Oncology · doi:10.1053/j.seminoncol.2005.03.015 · Cited by 38 · see citing works

TGF-β1 Gene Polymorphisms for Anticipating Radiation-Induced Pneumonitis in Non–Small-Cell Lung Cancer: Different Ethnic Association

Wang, L., & Bi, N. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2010.31.0458 · Cited by 36 · see citing works

Comparison of the effects of aromatase inhibitors and tamoxifen on radiation-induced lung toxicity: results of an experimental study

Yavaş, G., Yavaş, Ç., Acar, H., Toy, H., Yüce, D., & Ata, Ö. (2012) · Supportive Care in Cancer · doi:10.1007/s00520-012-1584-7 · Cited by 22 · see citing works

CD44 and Bak Expression in IL-6 or TNF-alpha Gene Knockout Mice After Whole Lung Irradiation

Sakai, M., Iwakawa, M., Iwakura, Y., et al. (2008) · Journal of Radiation Research · doi:10.1269/jrr.07087 · Cited by 11 · see citing works

Stereotactic Body Radiation Therapy Results in Promising Local Control in Patients with Recurrent or Secondary Lung Parenchyma Cancer after Definitive Conventional Thoracic Radiotherapy

Kelly, P., Balter, P. A., Rebueno, N. C. S., et al. (2009) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2009.07.373 · Cited by 5 · see citing works

Fibrosis: from mechanisms to medicines

Henderson, N. C., Rieder, F., & Wynn, T. A. (2020) · Nature · doi:10.1038/s41586-020-2938-9 · Cited by 1,868 · see citing works

Clinical research of distal bronchoalveolar lavage with plastic tubing and common bronchoalveolar lavage

Qiu, X., Zhang, J., Wang, Y., et al. (2009) · Chinese Journal of Asthma · doi:10.3760/cma.j.issn.1673-436x.2009.017.006

Reference values for bronchoalveolar lavage in children.

Ratjen, F. A. (2000) · PubMed · Cited by 2 · see citing works

Transpulmonary Thermodilution Enables to Detect Small Short-Term Changes in Extravascular Lung Water Induced by a Bronchoalveolar Lavage

Dres, M., Teboul, J., Guerin, L., et al. (2014) · Critical Care Medicine · doi:10.1097/ccm.0000000000000341 · Cited by 23 · see citing works

[Use of bronchoalveolar lavage for diagnosis of respiratory diseases].

Gruchała, J., & Górski, P. (1995) · PubMed · Cited by 1 · see citing works

Bronchoalveolar Lavage

Tekavec-Trkanjec, J., Peroš-Golubičić, T., Smojver‐Ježek, S., et al. (2006) · Springer eBooks · doi:10.1007/3-540-29835-5_2608