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Cited by 22Radiation Therapy and DosimetryEffects of Radiation ExposureAdvanced Radiotherapy Techniques

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Particle species dependence of cell survival RBE: Evident and not negligible

Open access
Friedrich, Thomas, Durante, Marco, Scholz, Michael·2013·Acta Oncologica
DOI 10.3109/0284186x.2013.767984
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Abstract

To the Editor,With great interest we noticed the work of Singers Sørensen, Overgaard and Bassler [1], where the authors question if the linear energy transfer (LET) of ion beams can serve as a uniq...

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Registry

Crossref · 10.3109/0284186x.2013.767984

Cites

2 of 2 references verified0 citation errors · 0 not checkable

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  • When multiple DSB in a DSB cluster are scored as a single DSB site, simulation results show patterns known from radiobiological studies, with ion-specific peaks in RBE for cell killing usually in 100-200 keV/μm.

    “When multiple DSB in a DSB cluster are scored as a single DSB site (an isolated DSB also being a single DSB site), the simulation results (Fig. 3c) show patterns known from radiobiological studies51, in which ion specific peaks in the RBE for cell killing are usually observed in the range from 100 to 200 keV/μm.”

    From Comprehensive track-structure based evaluation of DNA damage by light ions from radiotherapy-relevant energies down to stopping (2017) · cites this paper as [51]

    In “To the Editor” (page unavailable), Friedrich et al. report that cell-survival RBE depends on both LET and ion species, supporting the ion-specific aspect. Their discussion and Figure 1 caption do not report RBE peaks usually occurring at 100–200 keV/μm. The DSB-site scoring and simulation results are presented as the citing authors’ own work, not as findings attributed to this source. (LLM, conf=0.85)

    Experimental — accuracy not yet measured

  • Such behaviour is typically seen in LET-dependent cell killing across numerous cell lines.

    “Such behaviour is the one that is typically seen in LET-dependent cell killing, across numerous cell lines51.”

    From Comprehensive track-structure based evaluation of DNA damage by light ions from radiotherapy-relevant energies down to stopping (2017) · cites this paper as [51]

    In “To the Editor” (page unavailable), the paper reports that cell-survival RBE depends on LET and particle species. Its Figure 1, however, shows data for V79 cells, not numerous cell lines, so the claim’s breadth is not established by this copy. (LLM, conf=0.84)

    Experimental — accuracy not yet measured

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Citations

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Research works printed but not linked: 1

  1. Friedrich T,, 2012, J Radiat Res (Tokyo) Epub

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Metadata

Authors
Friedrich, T., Durante, M., & Scholz, M.
Affiliations
GSI Helmholtz Centre for Heavy Ion Research (DE)
Corresponding author
Friedrich, Thomas
ORCID
Venue
Acta Oncologica
Publisher
MJS Publishing, Medical Journals Sweden AB
Published
2013-02-15
Volume
52
Issue
3
Pages
589-603
ISSN
  • 0284-186X (ISSN-L)
  • 1651-226X
DOI
10.3109/0284186x.2013.767984
OpenAlex
W1995536144
Cited by
22
References
2
Citations by year
2025: 3 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 1 · 2017: 4 · 2016: 2 · 2015: 1 · 2014: 2 · 2013: 2
Type
journal article
Language
en
Open access
Locations
  • Acta Oncologica (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Physics and Astronomy › Radiation › Radiation Therapy and Dosimetry
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Effects of Radiation Exposure
  • Physical Sciences › Physics and Astronomy › Radiation › Advanced Radiotherapy Techniques
Keywords
relative biological effectiveness, particle species dependence, linear energy transfer, ion beams, cell survival, radiation biology
MeSH terms
Animals, Humans, Neoplasms, Protons, Photons, Linear Energy Transfer, Proton Therapy

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