Nordic guidelines 2014 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms
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BACKGROUND: The diagnostic work-up and treatment of patients with neuroendocrine neoplasms (NENs) has undergone major recent advances and new methods are currently introduced into the clinic. An update of the WHO classification has resulted in a new nomenclature dividing NENs into neuroendocrine tumours (NETs) including G1 (Ki67 index ≤ 2%) and G2 (Ki67 index 3-20%) tumours and neuroendocrine carcinomas (NECs) with Ki67 index > 20%, G3. Aim. These Nordic guidelines summarise the Nordic Neuroendocrine Tumour Group's current view on how to diagnose and treat NEN-patients and are meant to be useful in the daily practice for clinicians handling these patients.
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Some guidelines recommend the use of plasma CgA in diagnosis of NETs.
“Despite the diagnostic pitfalls, some guidelines [24,25,26] also recommend the use of plasma CgA in diagnosis of NETs, although no clinical data directly support this strategy.”
From Limited Diagnostic Utility of Chromogranin A Measurements in Workup of Neuroendocrine Tumors (2020) · cites this paper as [25]
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Limited Diagnostic Utility of Chromogranin A Measurements in Workup of Neuroendocrine Tumors
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- Authors
- Janson, E. T., Sorbye, H., Welin, S., Federspiel, B., Grønbæk, H., Hellman, P., Ladekarl, M., Langer, S. W., Mortensen, J., Schalin-Jäntti, C., Sundin, A., Sundlöv, A., Thiis-Evensen, E., & Knigge, U.
- Affiliations
- Uppsala University (SE)
- University of Copenhagen (DK)
- Aarhus University Hospital (DK)
- Skåne University Hospital (SE)
- Corresponding author
- Janson, Eva Tiensuu
- ORCID
- Venue
- Acta Oncologica
- Published
- 2014-08-20
- Volume
- 53
- Issue
- 10
- Pages
- 1284-1297
- ISSN
- 0284-186X (ISSN-L)
- 1651-226X
- OpenAlex
- W7214199439
- Cited by
- 0
- References
- 72
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Acta Oncologica (publishedVersion)
- PubMed (publishedVersion)
- Lund University Publications (Lund University) (submittedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Neuroendocrine Tumor Research Advances
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal Tumor Research and Treatment
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
- Keywords
- gastroenteropancreatic neuroendocrine tumors, neuroendocrine tumors, neuroendocrine carcinoma, Ki-67 proliferation index, WHO classification, diagnosis, treatment
- MeSH terms
- Antineoplastic Agents, Diagnostic Imaging, Gastrointestinal Neoplasms, Humans, Liver Neoplasms, Pancreatic Neoplasms, Prognosis, Biomarkers, Tumor, Carcinoma, Neuroendocrine, Neuroendocrine Tumors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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