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Cited by 245

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Pain Analysis in Patients with Fibromyalgia:Effects of intravenous morphine, lidocaine, and ketamine

Sörensen, J., Bengtsso, A., Bäckman, E., Henriksson, K. G., Bengtsson, M.·1995·Scandinavian Journal of Rheumatology

Abstract

Pain intensity, muscle strength, static muscle endurance, pressure pain threshold, and pain tolerance at tender points and control points were assessed in 31 patients with fibromyalgia (FM), before and after intravenous administration of morphine (9 patients), lidocaine (11 patients), and ketamine (11 patients). The three different studies were double-blind and placebo-controlled. The patients were classified as placebo-responders, responders (decrease in pain intensity by > 50%) and non-responders. The morphine test did not show any significant changes. The lidocaine test showed a pain decrease during and after the infusion. The ketamine test showed a significant reduction in pain intensity during and after the test period. Tenderness at tender points decreased and endurance increased significantly, while muscle strength remained unchanged. The present results support the hypothesis that the NMDA receptors are involved in pain mechanisms in fibromyalgia. These findings also suggest that central sensitization is present in FM and that tender points represent secondary hyperalgesia.

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Metadata

Authors
Sörensen, J., Bengtsso, A., Bäckman, E., Henriksson, K. G., & Bengtsson, M.
Venue
Scandinavian Journal of Rheumatology
Published
1995-01
Volume
24
Issue
6
Pages
360-365
ISSN
  • 0300-9742 (ISSN-L)
  • 1502-7732
OpenAlex
W2136571643
Cited by
245
References
2
FWCI
4.21
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Pain Analysis in Patients with Fibromyalgia:Effects of intravenous morphine, lidocaine, and ketamine. https://app.cochat.ai/papers/10.3109/03009749509095181
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Sörensen, J., Bengtsso, A., Bäckman, E., Henriksson, K. G., & Bengtsson, M. (1995). Pain Analysis in Patients with Fibromyalgia:Effects of intravenous morphine, lidocaine, and ketamine. Scandinavian Journal of Rheumatology. https://doi.org/10.3109/03009749509095181

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.