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Interspecies Pharmacokinetic Scaling and the Evolutionary-Comparative Paradigm
Abstract
(1984). Interspecies Pharmacokinetic Scaling and the Evolutionary-Comparative Paradigm. Drug Metabolism Reviews: Vol. 15, No. 5-6, pp. 1071-1121.
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Citations
Cites
Pleiotropy, natural selection, and the evolution of senescence
Williams, G. C. (1957) · Evolution · doi:10.2307/2406060 · Cited by 1,912
Cited by
Martignoni, M., Groothuis, G. M. M., & de Kanter, R. (2006) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1517/17425255.2.6.875 · Cited by 1,478
The Prediction of Human Pharmacokinetic Parameters from Preclinical and in Vitro Metabolism Data
Obach, R. S., Baxter, J. G., Liston, T. E., Silber, B. M., Jones, B. C., Macintyre, F., Rance, D. J., & Wastall, P. (1997) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)36999-x · Cited by 987
A Novel Strategy for Physiologically Based Predictions of Human Pharmacokinetics
Jones, H. M., Parrott, N., Jorga, K., & Lav??, T. (2006) · Clinical Pharmacokinetics · doi:10.2165/00003088-200645050-00006 · Cited by 352
Deng, R., Iyer, S., Theil, F.-P., Mortensen, D. L., Fielder, P. J., & Prabhu, S. (2011) · mAbs · doi:10.4161/mabs.3.1.13799 · Cited by 285
Ward, K. W., & Smith, B. R. (2004) · Drug Metabolism and Disposition · doi:10.1124/dmd.32.6.603 · Cited by 212
Lave, T. H., Dupin, S., Schmitt, C., Chou, R. C., Jaeck, D., & Coassolo, P. (1997) · Journal of Pharmaceutical Sciences · doi:10.1021/js960440h · Cited by 184
(1998) · PubMed · Cited by 176
MAHMOOD, I. (2007) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.05.015 · Cited by 170
Lav??, T., Coassolo, P., & Reigner, B. (1999) · Clinical Pharmacokinetics · doi:10.2165/00003088-199936030-00003 · Cited by 162
Dong, J. Q., Salinger, D. H., Endres, C. J., Gibbs, J. P., Hsu, C.-P., Stouch, B. J., Hurh, E., & Gibbs, M. A. (2011) · Clinical Pharmacokinetics · doi:10.2165/11537430-000000000-00000 · Cited by 156
Interspecies Scaling of Therapeutic Monoclonal Antibodies: Initial Look
Ling, J., Zhou, H., Jiao, Q., & Davis, H. M. (2009) · The Journal of Clinical Pharmacology · doi:10.1177/0091270009337134 · Cited by 144
The Pharmacokinetic Principles Behind Scaling from Preclinical Results to Phase I Protocols
Mahmood, I., & Balian, J. D. (1999) · Clinical Pharmacokinetics · doi:10.2165/00003088-199936010-00001 · Cited by 112
Mahmood, I., & Balian, J. D. (1996) · Journal of Pharmaceutical Sciences · doi:10.1021/js950400y · Cited by 105
Nagilla, R., & Ward, K. W. (2004) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.20169 · Cited by 96
Wajima, T., Yano, Y., Fukumura, K., & Oguma, T. (2004) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.20099 · Cited by 98
Prediction of Hepatic Metabolic Clearance: Comparison and Assessment of Prediction Models
Zuegge, J., Schneider, G., Coassolo, P., & Lav??, T. (2001) · Clinical Pharmacokinetics · doi:10.2165/00003088-200140070-00006 · Cited by 92
Prediction of metabolic drug clearance in humans:In vitro–in vivoextrapolationvsallometric scaling
Shiran, M. R., Proctor, N. J., Howgate, E. M., Rowland-Yeo, K., Tucker, G. T., & Rostami-Hodjegan, A. (2006) · Xenobiotica · doi:10.1080/00498250600761662 · Cited by 89
Scaling basic toxicokinetic parameters from rat to man.
Bachmann, K., Pardoe, D., & White, D. (1996) · Environmental Health Perspectives · doi:10.1289/ehp.96104400 · Cited by 90
Choi, G.-W., Lee, Y.-B., & Cho, H.-Y. (2019) · Pharmaceutics · doi:10.3390/pharmaceutics11040168 · Cited by 79
“Two-term method CL = θ(W)·(BW) (77) θ is a constant, which is determined by multiple regression analysis [91]”
MethodWang, J., Iyer, S., Fielder, P. J., Davis, J. D., & Deng, R. (2016) · Biopharmaceutics & Drug Disposition · doi:10.1002/bdd.1952 · Cited by 69
Predicting Pharmacokinetic Profiles Using in Silico Derived Parameters
Hosea, N. A., & Jones, H. M. (2013) · Molecular Pharmaceutics · doi:10.1021/mp300482w · Cited by 65
Mahmood, I. (1999) · Journal of Pharmacy and Pharmacology · doi:10.1211/0022357991773320 · Cited by 59
Prospective Predictions of Human Pharmacokinetics for Eighteen Compounds
Zhang, T., Heimbach, T., Lin, W., Zhang, J., & He, H. (2015) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.24373 · Cited by 56
Mahmood, I. (1998) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1998.tb06190.x · Cited by 53
Misconceptions and Issues Regarding Allometric Scaling during the Drug Development Process
Mahmood, I. (2018) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2018.1499725 · Cited by 35
Oitate, M., Nakayama, S., Ito, T., Kurihara, A., Okudaira, N., & Izumi, T. (2012) · Drug Metabolism and Pharmacokinetics · doi:10.2133/dmpk.dmpk-11-sh-059 · Cited by 35
Van den Bergh, A., Sinha, V., Gilissen, R., Straetemans, R., Wuyts, K., Morrison, D., Bijnens, L., & Mackie, C. (2011) · Clinical Pharmacokinetics · doi:10.2165/11587230-000000000-00000 · Cited by 33
Interspecies Scaling: Predicting Oral Clearance in Humans
Mahmood, I. (2002) · American Journal of Therapeutics · doi:10.1097/00045391-200201000-00008 · Cited by 33
Mahmood (2002) · Drug Metabolism and Drug Interactions · doi:10.1515/dmdi.2002.19.1.49 · Cited by 29
Metadata
- Authors
- Boxenbaum, H.
- Venue
- Drug Metabolism Reviews
- Publisher
- Informa UK Limited
- Published
- 1984-01-01
- Volume
- 15
- Issue
- 5-6
- Pages
- 1071-1121
- ISSN
- 0360-2532 (ISSN-L)
- 1097-9883
- OpenAlex
- W2041349258
- Cited by
- 267
- References
- 1
- FWCI
- 2.59
- Type
- journal article
- Language
- en
- Open access
- closed
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