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Pharmaceutical and Medical Aspects of Bioadhesive Systems for Drug Administration
Abstract
Bioadhesion could lead to the solution of bioavailability problems resulting from a too short stay of the pharmaceutical dosage form at the absorption or activity level of the active ingredient. Bioadhesion stages are: intimate contact resulting from a good wetting of the bioadhesion surface and the swelling of the bioadhesive polymer, then penetration of the bioadhesive into the crevice of the tissue surface or interpenetration of bioadhesive chains with those of the mucus, and finally low chemical bonds. date, the most important bioadhesive polymers are polycarbophil a Carbopol 934. Methods of studying bioadhesion are described as well as the existing bioadhesive dosage forms.
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Cited by
Ophthalmic drug delivery systems—Recent advances
Le Bourlais, C., Acar, L., Zia, H., Sado, P. A., Needham, T., & Leverge, R. (1998) · Progress in Retinal and Eye Research · doi:10.1016/s1350-9462(97)00002-5 · Cited by 698
The biopharmaceutical aspects of nasal mucoadhesive drug delivery
Ugwoke, M. I., Verbeke, N., & Kinget, R. (2001) · Journal of Pharmacy and Pharmacology · doi:10.1211/0022357011775145 · Cited by 355
Molecular aspects of muco- and bioadhesion:
Huang, Y., Leobandung, W., Foss, A., & Peppas, N. A. (2000) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00233-3 · Cited by 316
Self-citationThirawong, N., Nunthanid, J., Puttipipatkhachorn, S., & Sriamornsak, P. (2007) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2007.01.010 · Cited by 305
Ahmad, N., Ahmad, R., Alam, M. A., Samim, M., Iqbal, Z., & Ahmad, F. J. (2016) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2016.03.019 · Cited by 110
Metadata
- Authors
- Duchěne, D., Touchard, F., & Peppas, N. A.
- Venue
- Drug Development and Industrial Pharmacy
- Publisher
- Informa UK Limited
- Published
- 1988-01
- Volume
- 14
- Issue
- 2-3
- Pages
- 283-318
- ISSN
- 0363-9045 (ISSN-L)
- 1520-5762
- OpenAlex
- W1987324444
- Cited by
- 333
- References
- 0
- FWCI
- 2.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- Duchěne, D., Touchard, F., & Peppas, N. A. (1988). Pharmaceutical and Medical Aspects of Bioadhesive Systems for Drug Administration. Drug Development and Industrial Pharmacy. https://doi.org/10.3109/03639048809151972
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
