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Cited by 155Studies on Chitinases and ChitosanasesEnzyme Production and CharacterizationEnzyme Catalysis and Immobilization

The DOI matches its Crossref record; 278 of the 281 references it cites were found in a registry or an index, and 1 are not checked yet.

Chitinases: in agriculture and human healthcare

Nagpure, Anand, Choudhary, Bharti, Gupta, Rajinder K.·2014·Critical Reviews in Biotechnology
DOI 10.3109/07388551.2013.790874
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Abstract

Biological control of phytopathogenic fungi and insects continues to inspire the research and development of environmentally friendly bioactive alternatives. Potentially lytic enzymes, chitinases can act as a biocontrol agent against agriculturally important fungi and insects. The cell wall in fungi and protective covers, i.e. cuticle in insects shares a key structural polymer, chitin, a β-1,4-linked N-acetylglucosamine polymer. Therefore, it is advantageous to develop a common biocontrol agent against both of these groups. As chitin is absent in plants and mammals, targeting its metabolism will signify an eco-friendly strategy for the control of agriculturally important fungi and insects but is innocuous to mammals, plants, beneficial insects and other organisms. In addition, development of chitinase transgenic plant varieties probably holds the most promising method for augmenting agricultural crop protection and productivity, when properly integrated into traditional systems. Recently, human proteins with chitinase activity and chitinase-like proteins were identified and established as biomarkers for human diseases. This review covers the recent advances of chitinases as a biocontrol agent and its various applications including preparation of medically important chitooligosaccharides, bioconversion of chitin as well as in implementing chitinases as diagnostic and prognostic markers for numerous diseases and the prospect of their future utilization.

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Metadata

Authors
Nagpure, A., Choudhary, B., & Gupta, R. K.
Affiliations
Guru Gobind Singh Indraprastha University (IN)
Corresponding author
Gupta, Rajinder K.
ORCID
Gupta, Rajinder K.
Venue
Critical Reviews in Biotechnology
Publisher
Informa UK Limited
Published
2013-07-16
Volume
34
Issue
3
Pages
215-232
ISSN
  • 0738-8551 (ISSN-L)
  • 1549-7801
DOI
10.3109/07388551.2013.790874
OpenAlex
W2007954503
Cited by
145
References
281
Citations by year
2026: 5 · 2025: 16 · 2024: 6 · 2023: 18 · 2022: 14 · 2021: 20 · 2020: 14 · 2019: 12 · 2018: 9 · 2017: 12 · 2016: 9 · 2015: 7 · 2014: 1 · 2013: 2
FWCI
0.60
Type
journal article
Language
en
Open access
closed
Locations
  • Critical Reviews in Biotechnology (publishedVersion)
  • PubMed (publishedVersion)
Funders
Universidad de Guanajuato
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Studies on Chitinases and Chitosanases
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Enzyme Production and Characterization
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Enzyme Catalysis and Immobilization
Keywords
chitinase, biological control, plant pathogenic fungi, insect pests, chitin, chitooligosaccharides, transgenic plants, crop protection, disease biomarkers, fungal cell wall, insect cuticle
MeSH terms
Agriculture, Animals, Antifungal Agents, Antiprotozoal Agents, Chitinases, Delivery of Health Care, Humans, Pest Control, Biological

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CoChat. (2026). Citation check: Chitinases: in agriculture and human healthcare. https://app.cochat.ai/papers/10.3109/07388551.2013.790874
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Nagpure, A., Choudhary, B., & Gupta, R. K. (2014). Chitinases: in agriculture and human healthcare. Critical Reviews in Biotechnology. https://doi.org/10.3109/07388551.2013.790874

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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