The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.
Yeast killer toxins, molecular mechanisms of their action and their applications
Abstract
Killer toxins secreted by some yeast strains are the proteins that kill sensitive cells of the same or related yeast genera. In recent years, many new yeast species have been found to be able to produce killer toxins against the pathogenic yeasts, especially Candida albicans. Some of the killer toxins have been purified and characterized, and the genes encoding the killer toxins have been cloned and characterized. Many new targets including different components of cell wall, plasma membrane, tRNA, DNA and others in the sensitive cells for the killer toxin action have been identified so that the new molecular mechanisms of action have been elucidated. However, it is still unknown how some of the newly discovered killer toxins kill the sensitive cells. Studies on the killer phenomenon in yeasts have provided valuable insights into a number of fundamental aspects of eukaryotic cell biology and interactions of different eukaryotic cells. Elucidation of the molecular mechanisms of their action will be helpful to develop the strategies to fight more and more harmful yeasts.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“However, several of these toxins also inhibit or kill plant pathogenic fungi and were thus proposed for plant protection (Corbaci and Ucar 2018; Liu et al. 2015; Marquina et al. 2002; Perez et al. 2016).”
From Biocontrol yeasts: mechanisms and applications (2019) · cites this paper as Liu et al. 2015
Citations
Cites
Magliani, W., Conti, S., Gerloni, M., Bertolotti, D., & Polonelli, L. (1997) · Clinical Microbiology Reviews · doi:10.1128/cmr.10.3.369 · Cited by 322
Yeast viral killer toxins: lethality and self-protection
Schmitt, M. J., & Breinig, F. (2006) · Nature Reviews Microbiology · doi:10.1038/nrmicro1347 · Cited by 314
The viral killer system in yeast: from molecular biology to application
Schmitt, M., & Breinig, F. (2002) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2002.tb00614.x · Cited by 265
Perlova, O., Gerth, K., Kuhlmann, S., Zhang, Y., & Müller, R. (2009) · Microbial Cell Factories · doi:10.1186/1475-2859-8-1 · Cited by 252
Marquina, D., Santos, A., & Peinado, J. (2002) · International Microbiology · doi:10.1007/s10123-002-0066-z · Cited by 182
Santos, A., Mauro, M. S., Bravo, E., & Marquina, D. (2009) · Microbiology · doi:10.1099/mic.0.023663-0 · Cited by 135
Rodrı́guez-Cousiño, N., Maqueda, M., Ambrona, J., Zamora, E., Esteban, R., & Ramírez, M. (2011) · Applied and Environmental Microbiology · doi:10.1128/aem.02501-10 · Cited by 126
Kre1p, the Plasma Membrane Receptor for the Yeast K1 Viral Toxin
Breinig, F., Tipper, D. J., & Schmitt, M. (2002) · Cell · doi:10.1016/s0092-8674(02)00634-7 · Cited by 125
(1→6)-β- d -Glucan as Cell Wall Receptor for Pichia membranifaciens Killer Toxin
Santos, A., Marquina, D., Leal, J. A., & Peinado, J. M. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.5.1809-1813.2000 · Cited by 118
Santos, A., & Marquina, D. (2004) · Microbiology · doi:10.1099/mic.0.27071-0 · Cited by 116
Research works printed but not linked: 6
- Buzzini P, 2004, FEMS Microbiol Lett, 238, 359
- Naumov GI, 2011, Biotechnologiya, 3, 29
- Schaffrath R, 2005, Topics in current genetics, Vol 11: Microbial protein toxins, 131
- Wang XH, 2007, Acta Oceanol Sin, 26, 101
- Weiler F, 2003, FEMS Yeast Res, 3, 69
- Xu WJ, 2003, J Oceanol Zhejiang Province, 3, 209
Cited by
Sorted by citations
Items 101–111 of 111
Fernandes, J. (2023) · DNA and Cell Biology · doi:10.1089/dna.2023.0048
da Silva, J. C., Cerny, M. G., Nascimento, B. L., Martelli, E. C., Vieira, J., Marquezoni, R. D. S., Makita, M. T., Paula, C. R., Baroni, F. D. A., & Gandra, R. F. (2024) · Research in Veterinary Science · doi:10.1016/j.rvsc.2024.105319
Different species of yeast alter lifespan and fecundity of Drosophila melanogaster
Yakovleva, E. Y., Maximova, I. A., Merzlikin, D. S., Качалкин, А. В., & Markov, A. V. (2024) · Журнал общей биологии · doi:10.31857/s0044459624030013
Different Species of Yeast Alter the Lifespan and Fecundity of Drosophila melanogaster
Yakovleva, E. Y., Maximova, I. A., Merzlikin, D. S., Качалкин, А. В., & Markov, A. V. (2025) · Biology Bulletin Reviews · doi:10.1134/s207908642470021x
Zhao, X., & Chen, L. (2025) · Springer eBooks · doi:10.1007/978-3-031-95056-8_5
Pluskota, W. E., Jastrzebski, J., Paukszto, Ł., & Wachowska, U. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27010457
Use of viruses in wine technology
Cordero-Bueso, G. A. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-33914-1.00027-1
Pavlova, M., Shopska, V. N., Denkova-Kostova, R. S., Denkova, Z. R., & Kostov, G. A. (2026) · BIO Web of Conferences · doi:10.1051/bioconf/202623601004
Nematbakhsh, M., Koufopanou, V., Cass, A. E. G., & Burt, A. (2026) · Virus Evolution · doi:10.1093/ve/veag043
Unlock the Potential of Pichia in Coffee: Knowledge Transfer From Fermented Beverages
Elhalis, H. (2026) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.70607
Chi, Z., Liu, G.-L., & Chi, Z. (2026) · Springer eBooks · doi:10.1007/978-981-92-2607-8_12
Self-citation
Metadata
- Authors
- Liu, G.-L., Chi, Z., Wang, G.-Y., Wang, Z.-P., Li, Y., & Chi, Z.-M.
- Affiliations
- Ocean University of China (CN)
- Corresponding author
- Wang, Zhi-Peng
- Chi, Zhen-Ming
- Venue
- Critical Reviews in Biotechnology
- Publisher
- Informa UK Limited
- Published
- 2013-10-09
- Volume
- 35
- Issue
- 2
- Pages
- 222-234
- ISSN
- 0738-8551 (ISSN-L)
- 1549-7801
- OpenAlex
- W2098553908
- Cited by
- 111
- References
- 73
- Citations by year
- 2026: 7 · 2025: 6 · 2024: 14 · 2023: 13 · 2022: 9 · 2021: 8 · 2020: 19 · 2019: 13 · 2018: 8 · 2017: 6 · 2016: 4 · 2015: 2 · 2014: 2
- FWCI
- 0.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Critical Reviews in Biotechnology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Life Sciences › Immunology and Microbiology › Microbiology › Yeasts and Rust Fungi Studies
- Life Sciences › Immunology and Microbiology › Immunology › Toxin Mechanisms and Immunotoxins
- Keywords
- yeast killer toxin, Candida albicans, pathogenic yeasts, cell wall, plasma membrane, tRNA, DNA, toxin gene cloning
- MeSH terms
- Biotechnology, Candida, Killer Factors, Yeast
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
