CoChat
Sign Up
Cited by 24

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

ZFP36L1 is regulated by growth factors and cytokines in keratinocytes and influences their VEGF production

Hacker, Christine, Valchanova, Ralitsa, Adams, Stephanie, Munz, Barbara·2010·Growth Factors
DOI 10.3109/08977190903578660
Open this paper in CoChat — free account

Abstract

Keratinocyte-derived growth factors and cytokines play an important role in epidermal homeostasis and particularly in cutaneous wound repair. Thus, we analyzed a potential role of the ZFP36/tristetraprolin family of zinc finger proteins, which are targets of these factors, but also regulate their production, in keratinocytes. We show that expression of ZFP36, ZFP36L1, and ZFP36L2 is induced by a broad variety of growth factors and cytokines, and by scratch wounding. Since ZFP36L1 is a modulator of vascular endothelium growth factor (VEGF) mRNA stability, we subsequently used siRNA technology to inhibit ZFP36L1 gene expression. Notably, this treatment resulted in prolonged maintenance of elevated VEGF levels in HaCaT keratinocytes upon epidermal growth factor stimulation of these cells. Taken together, our results suggest an important role of ZFP36L1 in wound healing.

Overview

Integrity signals

Registry

Crossref · 10.3109/08977190903578660

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • ZFP36 family proteins bind to AREs and trigger degradation of several ARE-containing mRNAs, including PLK3 and VEGFA.

    “ZFP36 family proteins bind to AREs and trigger the degradation of several ARE-containing mRNAs, including PLK3 and vascular endothelial growth factor A (VEGFA) (7,8).”

    From ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK–RSK pathway (2014) · cites this paper as [8]

  • Endogenous ZFP36L1 interacts with PLK3 and VEGFA mRNAs.

    “We found that endogenous ZFP36L1 interacts with LDLR mRNA, and also with PLK3 and VEGFA mRNAs, previously identified ZFP36L1-interacting mRNAs (7,8).”

    From ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK–RSK pathway (2014) · cites this paper as [8]

  • ZFP36 family members interact with AREs containing a UAUUUAUU sequence and trigger degradation of several ARE-containing mRNAs, including PLK3 and VEGFA.

    “ZFP36L1 and ZFP36L2 belong to the family of CCCH tandem zinc finger proteins (the ZFP36 family), members of which interact with AREs containing a UAUUUAUU sequence and trigger the degradation of several ARE-containing mRNAs, including PLK3 and VEGFA (7,8,18,19).”

    From ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK–RSK pathway (2014) · cites this paper as [8]

  • PLK3 and VEGFA mRNAs are targets of ZFP36L1.

    “PLK3 and VEGFA mRNAs have recently been identified as targets of ZFP36L1 (7,8), whereas cMYC mRNA does not bind to ZFP36L1 or ZFP36L2.”

    From ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK–RSK pathway (2014) · cites this paper as [8]

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 79

  1. 10.1038/sj.jid.5700588 · DOI
  2. 10.1038/ng1987 · DOI
  3. 10.1093/nar/29.1.246 · DOI
  4. 10.1038/leu.2008.340 · DOI
  5. 10.1111/j.1524-475X.2008.00410.x · DOI · Paper page
  6. 10.1091/mbc.3.3.363 · DOI
  7. 10.1002/dvdy.20949 · DOI
  8. 10.1177/1538574408322755 · DOI
  9. 10.1095/biolreprod.105.040527 · DOI
  10. 10.1158/0008-5472.CAN-08-4238 · DOI
  11. 10.1128/MCB.26.6.2408-2418.2006 · DOI
  12. Brown LF, Olbricht SM, Berse B, Jackman RW, Matsueda G, Tognazzi KA, Manseau EJ, Dvorak HF, Van de Water L. 1995. Overexpression of vascular permeability factor (VPF/VEGF) and its endothelial cell receptors in delayed hypersensivity skin reactions. J Immunol. 154:2801–2807. · DOI
  13. 10.1016/j.ejcb.2007.07.005 · DOI
  14. 10.1038/oby.2008.65 · DOI
  15. 10.1073/pnas.83.6.1670 · DOI
  16. 10.1126/science.281.5379.1001 · DOI
  17. 10.1182/blood.V95.6.1891 · DOI
  18. 10.1074/jbc.M104953200 · DOI
  19. 10.1016/j.abb.2007.04.011 · DOI
  20. 10.1038/sj.onc.1207939 · DOI
  21. 10.1152/ajplung.2001.280.5.L841 · DOI
  22. 10.1016/0014-5793(95)00635-M · DOI
  23. 10.1093/emboj/16.2.295 · DOI
  24. 10.1002/cfg.239 · DOI
  25. 10.1084/jem.180.3.1141 · DOI
  26. DuBois RN, Bishop PR, Graves-Deal R, Coffey RJ. 1995. Transforming growth factor alpha regulation of two zinc finger-containing immediate early response genes in intestine. Cell Growth Differ. 6:523–529.
  27. 10.1074/jbc.M302759200 · DOI
  28. 10.1261/rna.748408 · DOI
  29. 10.1124/mol.104.008763 · DOI
  30. 10.1074/jbc.M606094200 · DOI
  31. 10.1074/jbc.270.21.12607 · DOI · Paper page
  32. 10.1046/j.1523-1755.2002.00237.x · DOI
  33. 10.1074/jbc.M001048200 · DOI
  34. 10.1046/j.0022-202x.2001.01573.x · DOI
  35. Gomperts M, Pascall JC, Brown KD. 1990. The nucleotide sequence of a cDNA encoding an EGF-inducible gene indicates the existence of a new family of mitogen-induced genes. Oncogene. 5:1081–1083.
  36. 10.1016/0014-5793(92)80825-2 · DOI
  37. 10.1038/nature07039 · DOI · Paper page
  38. 10.1016/S0923-1811(00)00141-9 · DOI
  39. 10.1128/MCB.00982-08 · DOI · Paper page
  40. 10.4049/jimmunol.180.12.8342 · DOI
  41. 10.1016/j.bcp.2004.11.027 · DOI
  42. 10.1038/sj.onc.1203474 · DOI
  43. 10.1038/sj.onc.1205526 · DOI
  44. 10.1016/0378-1119(92)90202-Z · DOI
  45. 10.1006/bbrc.1997.6849 · DOI
  46. 10.1016/S0021-9258(17)46259-4 · DOI
  47. 10.1074/jbc.M001696200 · DOI
  48. 10.1128/MCB.00945-06 · DOI
  49. Ma Q, Herschman HR. 1995. The yeast homologue YTIS11, of the mammalian TIS11 gene family is a non-essential, glucose repressible gene. Oncogene. 10:487–494.
  50. 10.1128/MCB.21.9.6461-6469.2001 · DOI
  51. 10.2119/2006-00024.Man · DOI
  52. 10.1111/j.1582-4934.2007.00112.x · DOI
  53. 10.1111/j.1365-2230.2008.03104.x · DOI
  54. 10.1016/S0014-5793(99)01601-4 · DOI
  55. 10.1038/sj.onc.1209645 · DOI
  56. 10.1126/science.276.5309.75 · DOI
  57. 10.1128/mcb.11.3.1409-1418.1991 · DOI
  58. 10.1074/jbc.M304856200 · DOI
  59. 10.1242/dev.01336 · DOI
  60. 10.1016/j.bbrc.2004.09.030 · DOI
  61. 10.1111/j.1432-0436.1989.tb00812.x · DOI
  62. 10.1182/blood-2005-07-3058 · DOI
  63. 10.1128/MCB.00679-06 · DOI
  64. 10.1093/emboj/cdf444 · DOI
  65. 10.1074/jbc.M606262200 · DOI
  66. 10.1128/MCB.24.14.6445-6455.2004 · DOI
  67. 10.1084/jem.20031701 · DOI
  68. 10.1093/nar/19.12.3454 · DOI
  69. 10.1016/S1074-7613(00)80411-2 · DOI
  70. 10.1074/jbc.M402059200 · DOI
  71. 10.1046/j.1523-1747.2002.01805.x · DOI
  72. Varnum BC, Lim RW, Sukhatme VP, Herschman HR. Nucleotide sequence of a cDNA encoding TIS11, a message induced in Swiss 3T3 cells by the tumor promoter tetradecanoyl phorbol acetate. Oncogene. 1989a; 4:119–120.
  73. 10.1128/mcb.9.8.3580-3583.1989 · DOI
  74. 10.1128/mcb.11.3.1754-1758.1991 · DOI
  75. 10.1111/1523-1747.ep12395564 · DOI
  76. 10.1016/S0002-9440(10)61213-8 · DOI
  77. 10.1016/j.bbrc.2006.07.213 · DOI
  78. Yin T, Yang YC. 1993. Protein tyrosine phosphorylation and activation of primary response genes by interleukin 11 in B9-TY1 cells. Cell Growth Differ. 4:603–609.
  79. 10.3748/wjg.v12.i31.4937 · DOI

Cited by

Sorted by citations

Metadata

Authors
Hacker, C., Valchanova, R., Adams, S., & Munz, B.
Affiliations
Institute of Physiology, Charité – University Medicine Berlin, Arnimallee 22, D-14195, Berlin, Germany
Venue
Growth Factors
Publisher
Informa UK Limited
Published
2010-02-19
Volume
28
Issue
3
Pages
178-190
ISSN
  • 0897-7194
  • 1029-2292
DOI
10.3109/08977190903578660
Cited by
24
References
1
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review