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Ecotoxicology of Organotin Compounds
Abstract
Organotin compounds are ubiquitous contaminants in the environment. The high biological activity of some compounds toward aquatic organisms lead to deleterious impacts in aquatic ecosystems. Here, the aquatic ecotoxicology of organotins is reviewed based on a multidisciplinary approach involving environmental chemical, toxicological, and ecological aspects. Basic results were obtained both with field and laboratory studies, and some of the most important recent results and conclusions are critically reviewed. The contamination of and fate in aquatic systems is reported and linked with effects at different levels of biological organization. Major emphasis is placed on the development of a concept of ecotoxicology that encompasses not only effect assessment alone, but also integrates environmental chemistry with aquatic toxicology. Thereby, the influence of speciation for bioavailability, basic modes of toxic action, and aquatic toxicity are discussed. This case study on organotins allows to a certain extent generalizations to ecotoxicology in general.
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“many tin compounds are toxic, severely limiting applications in biological settings such as the human body or ecosystems and requires careful removal of residuals.”
From Iron( ii ) carboxylates and simple carboxamides: an inexpensive and modular catalyst system for the synthesis of PLLA and PLLA-PCL block copolymers (2023) · cites this paper as [36]
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Metadata
- Authors
- Fent, K.
- Affiliations
- ETH Zurich (CH)
- Corresponding author
- Fent, Karl
- ORCID
- Fent, Karl
- Venue
- Critical Reviews in Toxicology
- Publisher
- Informa UK Limited
- Published
- 1996-01
- Volume
- 26
- Issue
- 1
- Pages
- 3-117
- ISSN
- 0045-6446 (ISSN-L)
- 1040-8444
- 1547-6898
- OpenAlex
- W1979164709
- Cited by
- 992
- References
- 395
- Citations by year
- 2026: 7 · 2025: 8 · 2024: 18 · 2023: 10 · 2022: 19 · 2021: 22 · 2020: 26 · 2019: 21 · 2018: 25 · 2017: 26 · 2016: 22 · 2015: 32 · 2014: 36 · 2013: 25 · 2012: 36
- FWCI
- 128.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Critical Reviews in Toxicology (publishedVersion)
- PubMed (publishedVersion)
- DORA Eawag (Swiss Federal Institute of Aquatic Science and Technology (Eawag)) (submittedVersion)
- Topics
- Physical Sciences › Engineering › Ocean Engineering › Marine Biology and Environmental Chemistry
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
- Keywords
- organotin compounds, aquatic ecotoxicology, environmental contamination, speciation, bioavailability, aquatic toxicity, environmental fate, aquatic ecosystems, environmental chemistry
- MeSH terms
- Animals, Ecology, Organotin Compounds, Tin, Water Pollutants, Chemical
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