Stress Physiology of Lactic Acid Bacteria.

Papadimitriou, Konstantinos; Alegría, Ángel; Bron, Peter A.; de Angelis, Maria; Gobbetti, Marco; Kleerebezem, Michiel; Lemos, José A.; Linares, Daniel M.; Ross, Paul; Stanton, Catherine; Turroni, Francesca; van Sinderen, Douwe; Varmanen, Pekka; Ventura, Marco; Zúñiga, Manuel; Tsakalidou, Effie; Kok, Jan

doi:10.1128/mmbr.00076-15

Cited by 916Probiotics and Fermented FoodsBacterial Genetics and BiotechnologyMicrobial Inactivation Methods

Stress Physiology of Lactic Acid Bacteria.

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Papadimitriou, Konstantinos, Alegría, Ángel, Bron, Peter A., de Angelis, Maria, Gobbetti, Marco, Kleerebezem, Michiel, Lemos, José A., Linares, Daniel M. +9 more·2016·Microbiology and Molecular Biology Reviews

DOI 10.1128/mmbr.00076-15PMC PMC4981675

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Abstract

Lactic acid bacteria (LAB) are important starter, commensal, or pathogenic microorganisms. The stress physiology of LAB has been studied in depth for over 2 decades, fueled mostly by the technological implications of LAB robustness in the food industry. Survival of probiotic LAB in the host and the potential relatedness of LAB virulence to their stress resilience have intensified interest in the field. Thus, a wealth of information concerning stress responses exists today for strains as diverse as starter (e.g., Lactococcus lactis), probiotic (e.g., several Lactobacillus spp.), and pathogenic (e.g., Enterococcus and Streptococcus spp.) LAB. Here we present the state of the art for LAB stress behavior. We describe the multitude of stresses that LAB are confronted with, and we present the experimental context used to study the stress responses of LAB, focusing on adaptation, habituation, and cross-protection as well as on self-induced multistress resistance in stationary phase, biofilms, and dormancy. We also consider stress responses at the population and single-cell levels. Subsequently, we concentrate on the stress defense mechanisms that have been reported to date, grouping them according to their direct participation in preserving cell energy, defending macromolecules, and protecting the cell envelope. Stress-induced responses of probiotic LAB and commensal/pathogenic LAB are highlighted separately due to the complexity of the peculiar multistress conditions to which these bacteria are subjected in their hosts. Induction of prophages under environmental stresses is then discussed. Finally, we present systems-based strategies to characterize the "stressome" of LAB and to engineer new food-related and probiotic LAB with improved stress tolerance.

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This adaptation is crucial for survival because it stimulates the production of additional energy and lowers the stress level, e.g., through alkalization of the cytosol under acidic conditions.
“This adaptation is crucial for survival because it stimulates the production of additional energy and lowers the stress level, e.g., through alkalization of the cytosol under acidic conditions (Papadimitriou et al., 2016).”
From Potential of Lactic Acid Bacteria Isolated From Different Forages as Silage Inoculants for Improving Fermentation Quality and Aerobic Stability (2020) · cites this paper as Papadimitriou et al., 2016

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Random Forests
Breiman, L. (2001) · Machine Learning · doi:10.1023/a:1010933404324 · Cited by 133,538 · see citing works
DNA Repair and Mutagenesis
Friedberg, E. C., Walker, G. C., Siede, W., Wood, R. D., Schultz, R. A., & Ellenberger, T. (2005) · doi:10.1128/9781555816704 · Cited by 5,683 · see citing works
Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd
Fleischmann, R. D., Adams, M. D., White, O. R., Clayton, R. A., Kirkness, E. F., Kerlavage, A. R., Bult, C. J., Tomb, J.-F., Dougherty, B. A., Merrick, J. M., et al. (1995) · Science · doi:10.1126/science.7542800 · Cited by 5,641 · see citing works
Two-Component Signal Transduction
Stock, A., Robinson, V. L., & Goudreau, P. N. (2000) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.69.1.183 · Cited by 3,653 · see citing works
The human microbiome: at the interface of health and disease
Cho, I., & Blaser, M. J. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3182 · Cited by 3,449 · see citing works
Guidelines for the evaluation of probiotics in food
Who, F. (2002) · Medical Entomology and Zoology · Cited by 1,843 · see citing works
Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger
Römling, U., Galperin, M. Y., & Gomelsky, M. (2013) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00043-12 · Cited by 1,679 · see citing works
Complete genome sequence of Lactobacillus plantarum WCFS1
Kleerebezem, M., Boekhorst, J., van Kranenburg, R., Molenaar, D., Kuipers, O. P., Leer, R., Tarchini, R., Peters, S. A., Sandbrink, H. M., Fiers, M. W. E. J., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0337704100 · Cited by 1,472 · see citing works
Self-citation
Comparative genomics of the lactic acid bacteria.
Makarova, K., Slesarev, A., Wolf, Y., Sorokin, A., Mirkin, B., Koonin, E., Pavlov, A., Pavlova, N., Karamychev, V., Polouchine, N., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607117103 · Cited by 1,391 · see citing works
Surviving the Acid Test: Responses of Gram-Positive Bacteria to Low pH
Cotter, P. D., & Hill, C. (2003) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.67.3.429-453.2003 · Cited by 1,378 · see citing works
The penicillin-binding proteins: structure and role in peptidoglycan biosynthesis
Sauvage, E., Kerff, F., Terrak, M., Ayala, J. A., & Charlier, P. (2008) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2008.00105.x · Cited by 1,322 · see citing works
(p)ppGpp: Still Magical?
Potrykus, K., & Cashel, M. (2008) · Annual Review of Microbiology · doi:10.1146/annurev.micro.62.081307.162903 · Cited by 1,170 · see citing works
The Complete Genome Sequence of the Lactic Acid Bacterium Lactococcus lactis ssp. lactis IL1403
Bolotin, A., Wincker, P., Mauger, S., Jaillon, O., Malarme, K., Weissenbach, J., Ehrlich, S. D., & Sorokin, A. (2001) · Genome Research · doi:10.1101/gr.gr-1697r · Cited by 1,139 · see citing works
The Complete Genome Sequence of the Lactic Acid Bacterium Lactococcus lactis ssp. lactis IL1403Preprint
Bolotin, A., Wincker, P., Mauger, S., Jaillon, O., Malarme, K., Weissenbach, J., Ehrlich, S. D., & Sorokin, A. (2001) · Genome Research · doi:10.1101/gr.169701 · Cited by 1,133 · see citing works
Bacterial Stress Responses
Storz, G., & Hengge, R. (2010) · ASM Press eBooks · doi:10.1128/9781555816841 · Cited by 1,107 · see citing works
Lactic acid bacteria of foods and their current taxonomy
Stiles, M. E., & Holzapfel, W. H. (1997) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(96)01233-0 · Cited by 1,100 · see citing works
Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome
Jones, B. V., Begley, M., Hill, C., Gahan, C. G. M., & Marchesi, J. R. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804437105 · Cited by 1,098 · see citing works
Oxidative stress responses in Escherichia coli and Salmonella typhimurium
Farr, S. B., & Kogoma, T. (1991) · Microbiological Reviews · doi:10.1128/mr.55.4.561-585.1991 · Cited by 1,091 · see citing works
Oxidative stress
Storz, G., & Imlayt, J. A. (1999) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(99)80033-2 · Cited by 1,077 · see citing works
Gram-Positive Pathogens
(2019) · ASM Press eBooks · doi:10.1128/9781683670131 · Cited by 1,012 · see citing works
The importance of the viable but non-culturable state in human bacterial pathogens
Li, L., Mendis, N., Trigui, H., Oliver, J. D., & Faucher, S. P. (2014) · Frontiers in Microbiology · doi:10.3389/fmicb.2014.00258 · Cited by 986 · see citing works
Role of Mobile DNA in the Evolution of Vancomycin-Resistant Enterococcus faecalis
Paulsen, I. T., Banerjei, L., Myers, G. S. A., Nelson, W. C., Seshadri, R., Read, T. D., Fouts, D. E., Eisen, J. A., Gill, S. R., Heidelberg, J. F., et al. (2003) · Science · doi:10.1126/science.1080613 · Cited by 930 · see citing works
Iron and Oxidative Stress in Bacteria
Touati, D. (2000) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1999.1518 · Cited by 924 · see citing works
Oxygen Toxicity: A Radical Explanation
Fridovich, I. (1998) · Journal of Experimental Biology · doi:10.1242/jeb.201.8.1203 · Cited by 850 · see citing works
Bacterial osmoadaptation: the role of osmolytes in bacterial stress and virulence
Sleator, R. D., & Hill, C. (2002) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2002.tb00598.x · Cited by 816 · see citing works
The Heat Shock Respons
Craig, E. A., & Schlesinger, M. J. (1985) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238509085135 · Cited by 809 · see citing works
Inorganic Polyphosphate: Essential for Growth and Survival
Rao, N. N., Gómez-García, M. R., & Kornberg, A. (2009) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.77.083007.093039 · Cited by 798 · see citing works
AAA+ Proteases: ATP-Fueled Machines of Protein Destruction
Sauer, R. T., & Baker, T. A. (2011) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060408-172623 · Cited by 763 · see citing works
Concentrations of Choline-Containing Compounds and Betaine in Common Foods
Zeisel, S. H., Mar, M.-H., Howe, J. C., & Holden, J. M. (2003) · The Journal of Nutrition · doi:10.1093/jn/133.5.1302 · Cited by 744 · see citing works
Controlling gene expression in response to stress
de Nadal, E., Ammerer, G., & Posas, F. (2011) · Nature Reviews Genetics · doi:10.1038/nrg3055 · Cited by 720 · see citing works
Roles of the Glutathione- and Thioredoxin-Dependent Reduction Systems in the Escherichia Coli and Saccharomyces Cerevisiae Responses to Oxidative Stress
Carmel‐Harel, O., & Storz, G. (2000) · Annual Review of Microbiology · doi:10.1146/annurev.micro.54.1.439 · Cited by 715 · see citing works
Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa
Bron, P. A., van Baarlen, P., & Kleerebezem, M. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2690 · Cited by 690 · see citing works
Self-citation
Penicillin-binding proteins and β-lactam resistance
Zapun, A., Contreras‐Martel, C., & Vernet, T. (2008) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2007.00095.x · Cited by 690 · see citing works
The lactic acid bacteria
Orla-Jensen, S. (1919) · Cited by 676 · see citing works
AI-2-mediated signalling in bacteria
Pereira, C. S., Thompson, J. A., & Xavier, K. B. (2012) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2012.00345.x · Cited by 675 · see citing works
HSP100/Clp proteins: a common mechanism explains diverse functions
Schirmer, E. C., Glover, J. R., Singer, M. A., & Lindquist, S. L. (1996) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(96)10038-4 · Cited by 673 · see citing works
Stress responses in lactic acid bacteria.
van de Guchte, M., Serror, P., Chervaux, C., Smokvina, T., Ehrlich, S. D., & Maguin, E. (2002) · PubMed · Cited by 668 · see citing works
Prophage Genomics
Canchaya, C. A., Proux, C., Fournous, G., Bruttin, A., & Brüssow, H. (2003) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.67.2.238-276.2003 · Cited by 663 · see citing works
Pressure-sensitive ion channel in Escherichia coli.
Martinac, B., Buechner, M., Delcour, A. H., Adler, J., & Kung, C. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.8.2297 · Cited by 656 · see citing works
Stress responses in lactic acid bacteria
van de Guchte, M., Serror, P., Chervaux, C., Smokvina, T., Ehrlich, S. D., & Maguin, E. (2002) · Antonie van Leeuwenhoek · doi:10.1023/a:1020631532202 · Cited by 648 · see citing works
Mutation as a Stress Response and the Regulation of Evolvability
Galhardo, R. S., Hastings, P. J., & Rosenberg, S. M. (2007) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409230701648502 · Cited by 643 · see citing works
SERINE β-LACTAMASES AND PENICILLIN-BINDING PROTEINS
Ghuysen, J. (1991) · Annual Review of Microbiology · doi:10.1146/annurev.mi.45.100191.000345 · Cited by 633 · see citing works
Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM
Altermann, E., Russell, W. M., Azcárate-Peril, M. A., Barrangou, R., Buck, B. L., McAuliffe, O. E., Souther, N. E., Dobson, A., Duong, T., Callanan, M. J., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409188102 · Cited by 594 · see citing works
The Structure of ClpP at 2.3 Å Resolution Suggests a Model for ATP-Dependent Proteolysis
Wang, J., Hartling, J. A., & Flanagan, J. M. (1997) · Cell · doi:10.1016/s0092-8674(00)80431-6 · Cited by 591 · see citing works
One-component systems dominate signal transduction in prokaryotes
Ulrich, L. E., Koonin, E. V., & Zhulin, I. B. (2004) · Trends in Microbiology · doi:10.1016/j.tim.2004.12.006 · Cited by 577 · see citing works
Efflux pumps as antimicrobial resistance mechanisms
Poole, K. (2007) · Annals of Medicine · doi:10.1080/07853890701195262 · Cited by 561 · see citing works
The TetR Family of Regulators
Cuthbertson, L., & Nodwell, J. R. (2013) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00018-13 · Cited by 554 · see citing works
Bile resistance mechanisms in Lactobacillus and Bifidobacterium
Ruiz, L., Margolles, A., & Sánchez, B. (2013) · Frontiers in Microbiology · doi:10.3389/fmicb.2013.00396 · Cited by 548 · see citing works
Survival of Probiotic Lactobacilli in Acidic Environments Is Enhanced in the Presence of Metabolizable Sugars
Corcoran, B. M., Stanton, C., Fitzgerald, G. F., & Ross, R. P. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.6.3060-3067.2005 · Cited by 547 · see citing works
Self-citation
Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera
Sun, Z., Harris, H. M. B., McCann, A., Guo, C., Argimón, S., Zhang, W., Yang, X., Jeffery, I. B., Cooney, J. C., Kagawa, T. F., et al. (2015) · Nature Communications · doi:10.1038/ncomms9322 · Cited by 543 · see citing works
Natural Genetic Transformation of Streptococcus mutans Growing in Biofilms
Li, Y.-H., Lau, P. C. Y., Lee, J. H., Ellen, R. P., & Cvitkovitch, D. G. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.3.897-908.2001 · Cited by 526 · see citing works
Occurrence of glutathione in bacteria
Fahey, R. C., Brown, W., Adams, W. B., & Worsham, M. B. (1978) · Journal of Bacteriology · doi:10.1128/jb.133.3.1126-1129.1978 · Cited by 522 · see citing works
THE STRUCTURE AND MODE OF ACTION OF GLYCOPEPTIDE ANTIBIOTICS OF THE VANCOMYCIN GROUP
Barna, J. C. J., & Williams, D. H. (1984) · Annual Review of Microbiology · doi:10.1146/annurev.mi.38.100184.002011 · Cited by 519 · see citing works
Autodigestion of lexA and phage lambda repressors.
Little, J. W. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.5.1375 · Cited by 513 · see citing works
Phage Genomics
Brüssow, H., & Hendrix, R. W. (2002) · Cell · doi:10.1016/s0092-8674(01)00637-7 · Cited by 508 · see citing works
Taxonomy and physiology of probiotic lactic acid bacteria
Klein, G., Pack, A., Bonaparte, C., & Reuter, G. (1998) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(98)00049-x · Cited by 505 · see citing works
Complete sequence and comparative genome analysis of the dairy bacterium Streptococcus thermophilus
Bolotin, A., Quinquis, B., Renault, P., Sorokin, A., Ehrlich, S. D., Kulakauskas, S., Lapidus, A. L., Goltsman, E., Mazur, M., Pusch, G. D., et al. (2004) · Nature Biotechnology · doi:10.1038/nbt1034 · Cited by 496 · see citing works
Role of amino acids in osmoregulation of non-halophilic bacteria
MEASURES, J. C. (1975) · Nature · doi:10.1038/257398a0 · Cited by 493 · see citing works
The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533
Pridmore, R. D., Berger, B. W., Desiere, F., Vilanova, D., Barretto, C., Pittet, A.-C., Zwahlen, M.-C., Rouvet, M., Altermann, E., Barrangou, R., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0307327101 · Cited by 485 · see citing works
Antibiotic Stress Induces Genetic Transformability in the Human Pathogen Streptococcus pneumoniae
Prudhomme, M., Attaiech, L., Sanchez, G., Martin, B., & Claverys, J. (2006) · Science · doi:10.1126/science.1127912 · Cited by 455 · see citing works
Recent Developments in Bacterial Cold-Shock Response
Phadtare, S. (2004) · Current Issues in Molecular Biology · doi:10.21775/cimb.006.125 · Cited by 454 · see citing works
The RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life.
Atkinson, G. C., Tenson, T., & Hauryliuk, V. (2011) · PLoS ONE · doi:10.1371/journal.pone.0023479 · Cited by 447 · see citing works
CELLULAR FUNCTIONS, MECHANISM OF ACTION, AND REGULATION OF FTSH PROTEASE
Ito, K., & Akiyama, Y. (2005) · Annual Review of Microbiology · doi:10.1146/annurev.micro.59.030804.121316 · Cited by 438 · see citing works
Global Analysis of the General Stress Response of Bacillus subtilis
Petersohn, A., Brigulla, M., Haas, S. A., Hoheisel, J. D., Völker, U., & Hecker, M. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.19.5617-5631.2001 · Cited by 433 · see citing works
Environmental stress responses in Lactobacillus: A review
Angelis, M. D., & Gobbetti, M. (2004) · PROTEOMICS · doi:10.1002/pmic.200300497 · Cited by 423 · see citing works
Self-citation
Kinship and Diversification of Bacterial Penicillin-Binding Proteins and β-Lactamases
Massova, I., & Mobashery, S. (1998) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.42.1.1 · Cited by 422 · see citing works
The complete genome sequence of Lactobacillus bulgaricus reveals extensive and ongoing reductive evolution
van de Guchte, M., Penaud, S., Grimaldi, C., Barbe, V., Bryson, K., Nicolas, P., Robert, C., Oztas, S., Mangenot, S., Couloux, A., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0603024103 · Cited by 417 · see citing works
Responses of lactic acid bacteria to oxygen
Condon, S. (1987) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1987.tb02465.x · Cited by 417 · see citing works
Probiotic Lactobacillus reuteri biofilms produce antimicrobial and anti-inflammatory factors
Jones, S. E., & Versalovic, J. A. (2009) · BMC Microbiology · doi:10.1186/1471-2180-9-35 · Cited by 417 · see citing works
Gram-Positive Pathogens
(2006) · ASM Press eBooks · doi:10.1128/9781555816513 · Cited by 416 · see citing works
Cell Wall Structure and Function in Lactic Acid Bacteria
Chapot-Chartier, M.-P., & Kulakauskas, S. (2014) · Microbial Cell Factories · doi:10.1186/1475-2859-13-s1-s9 · Cited by 410 · see citing works
Antibiotic efflux pumps
Françoise Van Bambeke, A., Balzi, E., & Tulkens, P. M. (2000) · Biochemical Pharmacology · doi:10.1016/s0006-2952(00)00291-4 · Cited by 404 · see citing works
CtsR, a novel regulator of stress and heat shock response, controls clp and molecular chaperone gene expression in Gram‐positive bacteria
Derré, I., Rapoport, G., & Msadek, T. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01152.x · Cited by 400 · see citing works
The role of lactobacilli and probiotics in maintaining vaginal health
Borges, S., Silva, J., & Teixeira, P. (2014) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-013-3064-9 · Cited by 397 · see citing works
Virulence control in group A Streptococcus by a two-component gene regulatory system: Global expression profiling and in vivo infection modeling
Graham, M., Smoot, L. M., Migliaccio, C. A. L., Virtaneva, K. I., Sturdevant, D. E., Porcella, S. F., Federle, M. J., Adams, G. J., Scott, J. R., & Musser, J. M. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.202353699 · Cited by 390 · see citing works
Discovering probiotic microorganisms: in vitro, in vivo, genetic and omics approaches
Papadimitriou, K., Ζουμποπούλου, Γ., Foligné, B., Alexandraki, V., Κάζου, Μ., Pot, B., & Tsakalidou, E. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00058 · Cited by 388 · see citing works
Self-citation
Cell envelope stress response in Gram-positive bacteria
Jordan, S., Hutchings, M. I., & Mascher, T. (2008) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2007.00091.x · Cited by 387 · see citing works
The extracellular biology of the lactobacilli
Kleerebezem, M., Pascal Hols, A., Bernard, E., Rolain, T., Zhou, M., Siezen, R. J., & Bron, P. A. (2009) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2009.00208.x · Cited by 381 · see citing works
Self-citation
Mechanosensitive Channels: What Can They Do and How Do They Do It?
Haswell, E. S., Phillips, R., & Rees, D. C. (2011) · Structure · doi:10.1016/j.str.2011.09.005 · Cited by 380 · see citing works
Mechanism of Action of Bacitracin: Complexation with Metal Ion and C 55 -Isoprenyl Pyrophosphate
Stone, K. J., & Strominger, J. L. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.12.3223 · Cited by 379 · see citing works
Understanding the structure and function of catalases: clues from molecular evolution and in vitro mutagenesis
Zámocký, M., & Koller, F. (1999) · Progress in Biophysics and Molecular Biology · doi:10.1016/s0079-6107(98)00058-3 · Cited by 376 · see citing works
Cyclic di-AMP: another second messenger enters the fray
Corrigan, R. M., & Gründling, A. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro3069 · Cited by 376 · see citing works
Mechanism of growth inhibition by free bile acids in lactobacilli and bifidobacteria
Kurdi, P., Kawanishi, K., Mizutani, K., & Yokota, A. (2006) · Journal of Bacteriology · doi:10.1128/jb.188.5.1979-1986.2006 · Cited by 364 · see citing works
Polyphosphate Is a Primordial Chaperone
Gray, M. J., Wholey, W.-Y., Wagner, N. O., Cremers, C. M., Mueller-Schickert, A., Hock, N. T., Krieger, A., Smith, E. M., Bender, R. A., Bardwell, J. C. A., et al. (2014) · Molecular Cell · doi:10.1016/j.molcel.2014.01.012 · Cited by 359 · see citing works
Functional single-cell analyses: flow cytometry and cell sorting of microbial populations and communities
Müller, S., & Nebe‐von‐Caron, G. (2010) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2010.00214.x · Cited by 356 · see citing works
New insights in the molecular biology and physiology of revealed by comparative genomics
Pascal Hols, A., Hancy, F., Fontaine, L., Grossiord, B., Prozzi, D., Leblond‐Bourget, N., Decaris, B., Bolotin, A., Delorme, C., & Ehrlich, S. D. (2005) · FEMS Microbiology Reviews · doi:10.1016/j.femsre.2005.04.008 · Cited by 354 · see citing works
Eukaryote-Like Serine/Threonine Kinases and Phosphatases in Bacteria
Pereira, S., Goss, L., & Dworkin, J. (2011) · Microbiology and Molecular Reviews · doi:10.1128/mmbr.00042-10 · Cited by 354 · see citing works
Production of Aroma Compounds in Lactic Fermentations
Smid, E. J., & Kleerebezem, M. (2014) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-030713-092339 · Cited by 354 · see citing works
Self-citation
Control of the shift from homolactic acid to mixed-acid fermentation in Lactococcus lactis: predominant role of the NADH/NAD+ ratio
Garrigues, C., Loubière, P., Lindley, N. D., & Cocaign‐Bousquet, M. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.17.5282-5287.1997 · Cited by 347 · see citing works
Small heat-shock proteins regulate membrane lipid polymorphism
Tsvetkova, N. M., Horváth, I., Török, Z., Wolkers, W. F., Balogi, Z., Shigapova, N., Crowe, L. M., Tablin, F., Vierling, E., Crowe, J. H., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.192468399 · Cited by 340 · see citing works
A model of efficiency: stress tolerance by Streptococcus mutans
Lemos, J. A. C., & Burne, R. A. (2008) · Microbiology · doi:10.1099/mic.0.2008/023770-0 · Cited by 325 · see citing works
Self-citation
Acid tolerance, proton permeabilities, and membrane ATPases of oral streptococci
Bender, G. R., Sutton, S., & Marquis, R. E. (1986) · Infection and Immunity · doi:10.1128/iai.53.2.331-338.1986 · Cited by 324 · see citing works
Bridging the gap between viable but non-culturable and antibiotic persistent bacteria
Ayrapetyan, M., Williams, T. C., & Oliver, J. D. (2014) · Trends in Microbiology · doi:10.1016/j.tim.2014.09.004 · Cited by 321 · see citing works
Manganese, superoxide dismutase, and oxygen tolerance in some lactic acid bacteria
Archibald, F. S., & Fridovich, I. (1981) · Journal of Bacteriology · doi:10.1128/jb.146.3.928-936.1981 · Cited by 319 · see citing works
The small heat shock proteins and their clients
Nakamoto, H., & Vı́gh, L. (2006) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-006-6321-2 · Cited by 316 · see citing works
Biodiversity-Based Identification and Functional Characterization of the Mannose-Specific Adhesin ofLactobacillus plantarum
Pretzer, G., Snel, J., Molenaar, D., Wiersma, A., Bron, P. A., Lambert, J., de Vos, W. M., van der Meer, R., Smits, M. A., & Kleerebezem, M. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.17.6128-6136.2005 · Cited by 316 · see citing works
Self-citation
Probiotic and Gut Lactobacilli and Bifidobacteria: Molecular Approaches to Study Diversity and Activity
Kleerebezem, M., & Vaughan, E. E. (2009) · Annual Review of Microbiology · doi:10.1146/annurev.micro.091208.073341 · Cited by 315 · see citing works
Self-citation
Adaptation of Streptococcus mutans and Enterococcus hirae to acid stress in continuous culture
Belli, W. A., & Marquis, R. E. (1991) · Applied and Environmental Microbiology · doi:10.1128/aem.57.4.1134-1138.1991 · Cited by 312 · see citing works
A novel double‐tryptophan peptide pheromone controls competence in Streptococcus spp. via an Rgg regulator
Mashburn‐Warren, L., Morrison, D. A., & Federle, M. J. (2010) · Molecular Microbiology · doi:10.1111/j.1365-2958.2010.07361.x · Cited by 312 · see citing works
Cell wall stress responses in Bacillus subtilis: the regulatory network of the bacitracin stimulon
Mascher, T., Margulis, N. G., Wang, T., Ye, R. W., & Helmann, J. D. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03786.x · Cited by 308 · see citing works
An alternative strategy for bacterial ribosome synthesis: Bacillus subtilis rRNA transcription regulation
Krásný, L., & Gourse, R. L. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600423 · Cited by 303 · see citing works
A VicRK Signal Transduction System in Streptococcus mutans Affects gtfBCD , gbpB , and ftf Expression, Biofilm Formation, and Genetic Competence Development
Senadheera, M. D., Guggenheim, B., Spatafora, G. A., Huang, Y.-C. C., Choi, J., Hung, D. C. I., Treglown, J. S., Goodman, S. D., Ellen, R. P., & Cvitkovitch, D. G. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.12.4064-4076.2005 · Cited by 298 · see citing works
Genomic Diversity and Versatility of Lactobacillus plantarum, a Natural Metabolic Engineer
Siezen, R. J., & van Hylckama Vlieg, J. E. (2011) · Microbial Cell Factories · doi:10.1186/1475-2859-10-s1-s3 · Cited by 294 · see citing works
Practical implications of lactate and pyruvate metabolism by lactic acid bacteria in food and beverage fermentations
Liu, S. (2003) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(02)00366-5 · Cited by 293 · see citing works
Transcriptional and Post-transcriptional Control of Cold-shock Genes
Gualerzi, C. O., Giuliodori, A. M., & Pon, C. L. (2003) · Journal of Molecular Biology · doi:10.1016/s0022-2836(03)00732-0 · Cited by 288 · see citing works
Clp ATPases and ClpP proteolytic complexes regulate vital biological processes in low GC, Gram‐positive bacteria
Frees, D., Savijoki, K., Varmanen, P., & Ingmer, H. (2007) · Molecular Microbiology · doi:10.1111/j.1365-2958.2007.05598.x · Cited by 288 · see citing works
Self-citation
Factors Influencing Biogenic Amines Accumulation in Dairy Products
Linares, D. M., del Río, B., Ladero, V., Martínez, N., Fernández, M., Martín, M. C., & Álvarez, M. A. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00180 · Cited by 286 · see citing works
Self-citation
The Genera Lactobacillus and Carnobacterium
Hammes, W. P., & Hertel, C. (2006) · Springer eBooks · doi:10.1007/0-387-30744-3_10 · Cited by 286 · see citing works
Alteration in cellular fatty acid composition as a response to salt, acid, oxidative and thermal stresses in Lactobacillus helveticus
Guerzoni, M. E., Lanciotti, R., & Cocconcelli, P. S. (2001) · Microbiology · doi:10.1099/00221287-147-8-2255 · Cited by 285 · see citing works
Comparative genomics of bacterial zinc regulons: Enhanced ion transport, pathogenesis, and rearrangement of ribosomal proteins
Panina, E. M., Mironov, A. A., & Gelfand, M. S. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1733691100 · Cited by 284 · see citing works
Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1.
van Veen, H. W., Venema, K., Bolhuis, H., Oussenko, I. A., Kok, J. W., Poolman, B., Driessen, A. J. M., & Konings, W. N. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.20.10668 · Cited by 282 · see citing works
Self-citation
Antibiotic-Inducible Promoter Regulated by the Cell Envelope Stress-Sensing Two-Component System LiaRS of Bacillus subtilis
Mascher, T., Zimmer, S. L., Smith, T.-A., & Helmann, J. D. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.8.2888-2896.2004 · Cited by 281 · see citing works
A chloride‐inducible acid resistance mechanism in Lactococcus lactis and its regulation
Sanders, J.-W., Leenhouts, K. J., Burghoorn, J., Brands, J. R., Venema, G., & Kok, J. (1998) · Molecular Microbiology · doi:10.1046/j.1365-2958.1998.00676.x · Cited by 276 · see citing works
Self-citation
Synechocystis HSP17 is an amphitropic protein that stabilizes heat-stressed membranes and binds denatured proteins for subsequent chaperone-mediated refolding
Török, Z., Goloubinoff, P., Horváth, I., Tsvetkova, N. M., Glatz, A., Balogh, G. E., Varvasovszki, V., Los, D. A., Vierling, E., Crowe, J. H., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.051619498 · Cited by 275 · see citing works
The GroE chaperonin machine is a major modulator of the CIRCE heat shock regulon of Bacillus subtilis
Mogk, A., Homuth, G., Scholz, C., Kim, L., Schmid, F. X., & Schumann, W. (1997) · The EMBO Journal · doi:10.1093/emboj/16.15.4579 · Cited by 256 · see citing works
YybT Is a Signaling Protein That Contains a Cyclic Dinucleotide Phosphodiesterase Domain and a GGDEF Domain with ATPase Activity
Rao, F., See, R. Y., Zhang, D., Toh, D. C., Ji, Q., & Liang, Z. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.040238 · Cited by 256 · see citing works
Respiration Capacity of the Fermenting Bacterium Lactococcus lactis and Its Positive Effects on Growth and Survival
Duwat, P., Sourice, S., Cesselin, B., Lamberet, G., Vido, K., Gaudu, P., Loir, Y. L., Violet, F., Loubière, P., & Gruss, A. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.15.4509-4516.2001 · Cited by 245 · see citing works
Energy transduction in lactic acid bacteria
Poolman, B. (1993) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.1993.tb00015.x · Cited by 245 · see citing works
Bet-hedging during bacterial diauxic shift
Solopova, A., van Gestel, J., Weissing, F. J., Bachmann, H., Teusink, B., Kok, J., & Kuipers, O. P. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1320063111 · Cited by 245 · see citing works
Self-citation
Survival of Oral Bacteria
Bowden, G. H., & Hamilton, I. R. (1998) · Critical Reviews in Oral Biology & Medicine · doi:10.1177/10454411980090010401 · Cited by 241 · see citing works
A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene
van Veen, H. W., Callaghan, R., Soceneantu, L., Sardini, A., Konings, W. N., & Higgins, C. F. (1998) · Nature · doi:10.1038/34669 · Cited by 239 · see citing works
Antibiotic-induced replication stress triggers bacterial competence by increasing gene dosage near the origin
Slager, J., Kjos, M., Attaiech, L., & Veening, J.-W. (2014) · Cell · doi:10.1016/j.cell.2014.01.068 · Cited by 237 · see citing works
Functional Microorganisms for Functional Food Quality
Gobbetti, M., Cagno, R. D., & Angelis, M. D. (2010) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2010.499770 · Cited by 236 · see citing works
Self-citation
Heat and Osmotic Stress Responses of Probiotic Lactobacillus rhamnosus HN001 (DR20) in Relation to Viability after Drying
Prasad, J., McJarrow, P., & Gopal, P. K. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.2.917-925.2003 · Cited by 231 · see citing works
Cofactor Engineering: a Novel Approach to Metabolic Engineering in Lactococcus lactis by Controlled Expression of NADH Oxidase
de Felipe, F. L., Kleerebezem, M., de Vos, W. M., & Hugenholtz, J. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.15.3804-3808.1998 · Cited by 223 · see citing works
Self-citation
Responses of Cariogenic Streptococci to Environmental Stresses
Lemos, J. A. C., Abranches, J., & Burne, R. A. (2005) · Current Issues in Molecular Biology · doi:10.21775/cimb.007.095 · Cited by 221 · see citing works
Self-citation
Protection mechanisms of sugars during different stages of preparation process of dried lactic acid starter cultures
Santivarangkna, C., Higl, B., & Foerst, P. (2008) · Food Microbiology · doi:10.1016/j.fm.2007.12.004 · Cited by 221 · see citing works
CovS/CovR of group B streptococcus: a two‐component global regulatory system involved in virulence
Lamy, M., Zouine, M., Fert, J., Vergassola, M., Couvé, E., Pellegrini, E., Glaser, P., Kunst, F., Msadek, T., Trieu‐Cuot, P., et al. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04365.x · Cited by 219 · see citing works
Characterization of the novel nisin-sucrose conjugative transposon Tn5276 and its insertion in Lactococcus lactis
Rauch, P. J. G., & de Vos, W. M. (1992) · Journal of Bacteriology · doi:10.1128/jb.174.4.1280-1287.1992 · Cited by 218 · see citing works
A Novel Pheromone Quorum-Sensing System Controls the Development of Natural Competence in Streptococcus thermophilus and Streptococcus salivarius
Fontaine, L., Boutry, C., de Frahan, M. H., Delplace, B., Fremaux, C., Horvath, P., Boyaval, P., & Pascal Hols, A. (2009) · Journal of Bacteriology · doi:10.1128/jb.01251-09 · Cited by 217 · see citing works
Streptococcus mutans: a new Gram-positive paradigm?
Lemos, J. A. C., Quivey, R. G., Koo, H., & Abranches, J. (2013) · Microbiology · doi:10.1099/mic.0.066134-0 · Cited by 216 · see citing works
Self-citation
Arginine deiminase system and bacterial adaptation to acid environments
Marquis, R. E., Bender, G. R., Murray, D. R. P., & Wong, A. (1987) · Applied and Environmental Microbiology · doi:10.1128/aem.53.1.198-200.1987 · Cited by 215 · see citing works
Physiological and Transcriptional Response ofLactobacillus caseiATCC 334 to Acid Stress
Broadbent, J. R., Larsen, R. L., Deibel, V., & Steele, J. L. (2010) · Journal of Bacteriology · doi:10.1128/jb.01618-09 · Cited by 215 · see citing works
Induction of heat shock proteins DnaK, GroEL, and GroES by salt stress in Lactococcus lactis
Kilstrup, M., Jacobsen, S., Hammer, K., & Vogensen, F. K. (1997) · Applied and Environmental Microbiology · doi:10.1128/aem.63.5.1826-1837.1997 · Cited by 214 · see citing works
vanM , a New Glycopeptide Resistance Gene Cluster Found in Enterococcus faecium
Xu, X., Lin, D., Yan, G., Ye, X., Wu, S., Guo, Y. P., Zhu, D., Hu, F., Zhang, Y., Wang, F., et al. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01710-09 · Cited by 213 · see citing works
Where are the pseudogenes in bacterial genomes?
Lawrence, J. G., Hendrix, R. W., & Casjens, S. (2001) · Trends in Microbiology · doi:10.1016/s0966-842x(01)02198-9 · Cited by 212 · see citing works
The MscS and MscL Families of Mechanosensitive Channels Act as Microbial Emergency Release Valves
Booth, I. R., & Blount, P. (2012) · Journal of Bacteriology · doi:10.1128/jb.00576-12 · Cited by 212 · see citing works
HtrA is the unique surface housekeeping protease in Lactococcus lactis and is required for natural protein processing
Poquet, I., Saint, V., Seznec, E., Simoes, N., Bolotin, A., & Gruss, A. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01757.x · Cited by 212 · see citing works
Longitudinal analysis of the group A Streptococcus transcriptome in experimental pharyngitis in cynomolgus macaques
Virtaneva, K. I., Porcella, S. F., Graham, M., Ireland, R. M., Johnson, C. A., Ricklefs, S., Babar, I., Parkins, L. D., Romero, R. A., Corn, G. J., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503671102 · Cited by 211 · see citing works
Stress and the Single Cell: Intrapopulation Diversity Is a Mechanism to Ensure Survival upon Exposure to Stress
Booth, I. R. (2002) · International Journal of Food Microbiology · doi:10.1016/s0168-1605(02)00239-8 · Cited by 211 · see citing works
Proteomics and Transcriptomics Characterization of Bile Stress Response in Probiotic Lactobacillus rhamnosus GG
Koskenniemi, K., Laakso, K., Koponen, J., Kankainen, M., Greco, D., Auvinen, P., Savijoki, K., Nyman, T. A., Surakka, A., Salusjärvi, T., et al. (2010) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m110.002741 · Cited by 210 · see citing works
Self-citation
Acid‐ and multistress‐resistant mutants of Lactococcus lactis : identification of intracellular stress signals
Rallu, F., Gruss, A., Ehrlich, S. D., & Maguin, E. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01711.x · Cited by 209 · see citing works
Extracellular superoxide production by Enterococcus faecalis requires demethylmenaquinone and is attenuated by functional terminal quinol oxidases
Huycke, M. M., Moore, D., Joyce, W., Wise, P., Shepard, L., Kotake, Y., & Gilmore, M. S. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02638.x · Cited by 209 · see citing works
Functional genomics of lactic acid bacteria: from food to health
Douillard, F. P., & de Vos, W. M. (2014) · Microbial Cell Factories · doi:10.1186/1475-2859-13-s1-s8 · Cited by 209 · see citing works
Mixed-Culture Transcriptome Analysis Reveals the Molecular Basis of Mixed-Culture Growth in Streptococcus thermophilus and Lactobacillus bulgaricus
Sieuwerts, S., Douwe Molenaar, B., van Hijum, S. A. F. T., Beerthuyzen, M. M., Stevens, M. J. A., Janssen, P. W. M., Ingham, C. J., de Bok, F. A. M., de Vos, W. M., & Vlieg, J. E. T. V. H. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.01122-10 · Cited by 209 · see citing works
High tolerance of wild Lactobacillus plantarum and Oenococcus oeni strains to lyophilisation and stress environmental conditions of acid pH and ethanol
G-Alegrı́a, E., López‐Alfaro, I., Ruiz-Sanz, J. I., SÃ¡enz, J., FernÃ¡ndez, E., Zarazaga, M., Dizy, M., Torres, C., & Ruiz‐Larrea, F. (2003) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(03)00854-1 · Cited by 206 · see citing works
Thermoprotection by glycine betaine and choline
Caldas, T. D., Demont-Caulet, N., Ghazi, A., & Richarme, G. (1999) · Microbiology · doi:10.1099/00221287-145-9-2543 · Cited by 200 · see citing works
The role of the gastrointestinal microbiome in Helicobacter pylori pathogenesis
Sheh, A., & Fox, J. G. (2013) · Gut Microbes · doi:10.4161/gmic.26205 · Cited by 198 · see citing works
Aerobic Respiration Metabolism in Lactic Acid Bacteria and Uses in Biotechnology
Pedersen, M. B., Gaudu, P., Lechardeur, D., Petit, M.-A., & Gruss, A. (2012) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-022811-101255 · Cited by 197 · see citing works
The BceRS two‐component regulatory system induces expression of the bacitracin transporter, BceAB, in Bacillus subtilis
Ohki, R., Giyanto, Tateno, K., Masuyama, W., Moriya, S., Kobayashi, K., & Ogasawara, N. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03653.x · Cited by 196 · see citing works
Citrate Fermentation by Lactococcus and Leuconostoc spp
Starrenburg, M. J. C., & Hugenholtz, J. (1991) · Applied and Environmental Microbiology · doi:10.1128/aem.57.12.3535-3540.1991 · Cited by 194 · see citing works
Oxidative stress protection by polyphosphate—new roles for an old player
Gray, M. J., & Jakob, U. (2015) · Current Opinion in Microbiology · doi:10.1016/j.mib.2014.12.004 · Cited by 194 · see citing works
A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus
Shelburne, S. A., Keith, D. B., Horstmann, N., Sumby, P., Davenport, M. T., Graviss, E. A., Brennan, R. G., & Musser, J. M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0711767105 · Cited by 194 · see citing works
Exchange of glutamate and gamma-aminobutyrate in a Lactobacillus strain
Higuchi, T., Hayashi, H., & Abe, K. (1997) · Journal of Bacteriology · doi:10.1128/jb.179.10.3362-3364.1997 · Cited by 190 · see citing works
The long and short of it – polyphosphate, PPK and bacterial survival
Brown, M. R., & Kornberg, A. (2008) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2008.04.005 · Cited by 190 · see citing works
Protective Effect of Sucrose and Sodium Chloride for Lactococcus lactis during Sublethal and Lethal High-Pressure Treatments
Molina-Höppner, A., Doster, W., Vogel, R. F., & Gänzle, M. G. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.4.2013-2020.2004 · Cited by 189 · see citing works
On the osmotic signal and osmosensing mechanism of an ABC transport system for glycine betaine
van der Heide, T., Stuart, M. C. A., & Poolman, B. (2001) · The EMBO Journal · doi:10.1093/emboj/20.24.7022 · Cited by 188 · see citing works
Alkaline shock induces the Bacillus subtilisσW regulon
Wiegert, T., Homuth, G., Versteeg, S., & Schumann, W. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02489.x · Cited by 187 · see citing works
Mechanisms of multidrug transporters
Bolhuis, H., van Veen, H. W., Poolman, B., Driessen, A. J. M., & Konings, W. N. (1997) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.1997.tb00345.x · Cited by 187 · see citing works
The Lactococcus lactis CodY Regulon
den Hengst, C. D., van Hijum, S. A. F. T., Geurts, J. M. W., Nauta, A., Kok, J., & Kuipers, O. P. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m502349200 · Cited by 187 · see citing works
Self-citation
Catabolite Control Protein A (CcpA) Contributes to Virulence and Regulation of Sugar Metabolism in Streptococcus pneumoniae
Iyer, R., Baliga, N. S., & Camilli, A. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.24.8340-8349.2005 · Cited by 186 · see citing works
Life Under Stress: The Probiotic Stress Response and How it may be Manipulated
Corcoran, B., Stanton, C., Fitzgerald, G. F., & Ross, R. P. (2008) · Current Pharmaceutical Design · doi:10.2174/138161208784480225 · Cited by 185 · see citing works
Self-citation
The Molecular Alarmone (p)ppGpp Mediates Stress Responses, Vancomycin Tolerance, and Virulence inEnterococcus faecalis
Abranches, J., Martinez, A. R., Kajfasz, J. K., Chávez, V., Garsin, D. A., & Lemos, J. A. C. (2009) · Journal of Bacteriology · doi:10.1128/jb.01726-08 · Cited by 180 · see citing works
Self-citation
Enhancing the stress responses of probiotics for a lifestyle from gut to product and back again
Mills, S., Stanton, C., Fitzgerald, G. F., & Ross, R. P. (2011) · Microbial Cell Factories · doi:10.1186/1475-2859-10-s1-s19 · Cited by 180 · see citing works
Self-citation
Metabolic Responses of Lactobacillus plantarum Strains during Fermentation and Storage of Vegetable and Fruit Juices
Filannino, P., Cardinali, G., Rizzello, C. G., Buchin, S., Angelis, M. D., Gobbetti, M., & Cagno, R. D. (2014) · Applied and Environmental Microbiology · doi:10.1128/aem.03885-13 · Cited by 179 · see citing works
Self-citation
Bacitracin sensing in Bacillus subtilis
Rietkötter, E., Hoyer, D., & Mascher, T. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2008.06194.x · Cited by 178 · see citing works
Interplay of the Serine/Threonine-Kinase StkP and the Paralogs DivIVA and GpsB in Pneumococcal Cell Elongation and Division
Fleurie, A., Manuse, S., Zhao, C., Campo, N., Cluzel, C., Lavergne, J., Freton, C., Combet, C., Guiral, S., Soufi, B., et al. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004275 · Cited by 177 · see citing works
Bacterial osmosensing: roles of membrane structure and electrostatics in lipid–protein and protein–protein interactions
Poolman, B., Spitzer, J. J., & Wood, J. M. (2004) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2004.06.013 · Cited by 177 · see citing works
Effect of acid stress on protein expression and phosphorylation in Lactobacillus rhamnosus GG
Koponen, J., Laakso, K., Koskenniemi, K., Kankainen, M., Savijoki, K., Nyman, T. A., de Vos, W. M., Tynkkynen, S., Kalkkinen, N., & Varmanen, P. (2011) · Journal of Proteomics · doi:10.1016/j.jprot.2011.11.009 · Cited by 176 · see citing works
Self-citation
Histamine-Producing Pathway Encoded on an Unstable Plasmid in Lactobacillus hilgardii 0006
Lucas, P., Wolken, W. A. M., Claisse, O., Lolkema, J. S., & Lonvaud‐Funel, A. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.3.1417-1424.2005 · Cited by 176 · see citing works
cAMP, c-di-GMP, c-di-AMP and now cGMP: bacteria use them all!
Gomelsky, M. (2010) · Molecular Microbiology · doi:10.1111/j.1365-2958.2010.07514.x · Cited by 175 · see citing works
Regulation of Streptococcus pneumoniae clp Genes and Their Role in Competence Development and Stress Survival
Chastanet, A., Prudhomme, M., Claverys, J., & Msadek, T. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.24.7295-7307.2001 · Cited by 175 · see citing works
Comparative proteomic analysis of Lactobacillus plantarumfor the identification of key proteins in bile tolerance
Hamon, E., Horvatovich, P. L., Izquierdo, E., Bringel, F., Marchioni, E., Werner, D., & Ennahar, S. (2011) · BMC Microbiology · doi:10.1186/1471-2180-11-63 · Cited by 174 · see citing works
Getting to the route of Helicobacter pylori treatment
Goddard, A. F. (1998) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/42.1.1 · Cited by 172 · see citing works
Spx-RNA Polymerase Interaction and Global Transcriptional Control during Oxidative Stress
Zuber, P. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.7.1911-1918.2004 · Cited by 171 · see citing works
Intramembrane-sensing histidine kinases: a new family of cell envelope stress sensors in Firmicutes bacteria
Mascher, T. (2006) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2006.00444.x · Cited by 171 · see citing works
Microbial domestication signatures of Lactococcus lactis can be reproduced by experimental evolution
Bachmann, H., Starrenburg, M. J. C., Molenaar, D., Kleerebezem, M., & van Hylckama Vlieg, J. E. T. (2012) · Genome Research · doi:10.1101/gr.121285.111 · Cited by 170 · see citing works
Self-citation
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Perry, J. A., Jones, M. B., Peterson, S. N., Cvitkovitch, D. G., & Levesque, C. M. (2009) · Molecular Microbiology · doi:10.1111/j.1365-2958.2009.06693.x · Cited by 165 · see citing works
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A Stress-Inducible Quorum-Sensing Peptide Mediates the Formation of Persister Cells with Noninherited Multidrug Tolerance
Leung, V., & Levesque, C. M. (2012) · Journal of Bacteriology · doi:10.1128/jb.06707-11 · Cited by 162 · see citing works
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The cop operon is required for copper homeostasis and contributes to virulence in Streptococcus pneumoniae
Shafeeq, S., Yesilkaya, H., Kloosterman, T. G., Narayanan, G., Wandel, M., Andrew, P. W., Kuipers, O. P., & Morrissey, J. A. (2011) · Molecular Microbiology · doi:10.1111/j.1365-2958.2011.07758.x · Cited by 157 · see citing works
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Thioredoxin reductase is a key factor in the oxidative stress response of Lactobacillus plantarum WCFS1
Serrano, L., Douwe Molenaar, B., Wels, M., Teusink, B., Bron, P. A., de Vos, W. M., & Smid, E. J. (2007) · Microbial Cell Factories · doi:10.1186/1475-2859-6-29 · Cited by 156 · see citing works
Self-citation
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Cationic antimicrobial peptides elicit a complex stress response in Bacillus subtilis that involves ECF-type sigma factors and two-component signal transduction systems
Pietiäinen, M., Gardemeister, M., Mecklin, M., Leskelä, S., Sarvas, M., & Kontinen, V. P. (2005) · Microbiology · doi:10.1099/mic.0.27761-0 · Cited by 151 · see citing works
Stress response in Lactococcus lactis: cloning, expression analysis, and mutation of the lactococcal superoxide dismutase gene
Sanders, J.-W., Leenhouts, K. J., Haandrikman, A. J., Venema, G., & Kok, J. (1995) · Journal of Bacteriology · doi:10.1128/jb.177.18.5254-5260.1995 · Cited by 151 · see citing works
Self-citation
Functional versatility in the CRP-FNR superfamily of transcription factors: FNR and FLP
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Broadbent, J. R., Neeno-Eckwall, E. C., Stahl, B., Tandee, K., Cai, H., Morovic, W., Horvath, P., Heidenreich, J., Perna, N. T., Barrangou, R., et al. (2012) · BMC Genomics · doi:10.1186/1471-2164-13-533 · Cited by 149 · see citing works
Genomic and Genetic Characterization of the Bile Stress Response of ProbioticLactobacillus reuteriATCC 55730
Whitehead, K. J., Versalovic, J. A., Roos, S., & Britton, R. A. (2008) · Applied and Environmental Microbiology · doi:10.1128/aem.02259-07 · Cited by 148 · see citing works
Contribution of Glutathione Peroxidase to the Virulence of Streptococcus pyogenes
Brenot, A., King, K. Y., Janowiak, B. E., Griffith, O. W., & Caparon, M. G. (2003) · Infection and Immunity · doi:10.1128/iai.72.1.408-413.2004 · Cited by 148 · see citing works

Flagged first, then by citations

Research works printed but not linked: 3

Henick-Kling T, Cox DJ, Olsen EB. 1991. Production de l'energie durant la fermentation malolactique. Rev Fr Oenol 132:63–66.
Aprea G, Mullan WMA, Mullan A, Murru N, Tozzi M, Cortesi ML. 2005. Isolation of polyphosphate-accumulating lactic acid bacteria from natural whey starters. Milchwissenschaft 60:256–258.
Lim B, Gross CA. 2011. Cellular response to heat shock and cold shock, p 93–114. In Storz G, Hengge R (ed), Bacterial stress responses, 2nd ed. ASM Press, Washington, DC.

Sorted by citations

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Self-citation
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Cirlini, M., Ricci, A., Galaverna, G., & Lazzi, C. (2019) · LWT · doi:10.1016/j.lwt.2019.108779 · Cited by 72 · see citing works
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Zuo, F., Chen, S., & Marcotte, H. (2020) · Biotechnology Advances · doi:10.1016/j.biotechadv.2020.107654 · Cited by 71 · see citing works
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Gammoh, S., Alu'datt, M. H., Tranchant, C. C., Al-U'datt, D. G. F., Alhamad, M. N., Rababah, T., Kubow, S. J., Haddadin, M. S. Y., Ammari, Z., Maghaydah, S., et al. (2020) · LWT · doi:10.1016/j.lwt.2020.109501 · Cited by 69 · see citing works
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Kok, J., van Gijtenbeek, L. A., de Jong, A., van der Meulen, S. B., Solopova, A., & Kuipers, O. P. (2017) · FEMS Microbiology Reviews · doi:10.1093/femsre/fux028 · Cited by 69 · see citing works
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Gong, L.-C., Ren, C., & Xu, Y. (2019) · Microbial Cell Factories · doi:10.1186/s12934-019-1157-2 · Cited by 68 · see citing works
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Liu, J., Chan, S. H. J., Chen, J., Solem, C., & Jensen, P. R. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00876 · Cited by 68 · see citing works
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Qin, Z., Yu, S., Chen, J., & Zhou, J. (2021) · Biotechnology Advances · doi:10.1016/j.biotechadv.2021.107863 · Cited by 66 · see citing works
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Xu, J., Guo, L., Zhao, N., Meng, X., Zhang, J., Wang, T., Wei, X., & Fan, M. (2022) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2021.2025335 · Cited by 65 · see citing works
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Fu, N., Huang, S., Xiao, J., & Chen, X. D. (2018) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2018.02.003 · Cited by 64 · see citing works
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Verce, M., Schoonejans, J., Aguirre, C. H., Bravo, R. M., Vuyst, L. D., & Weckx, S. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.641185 · Cited by 63 · see citing works
Lactobacilli and human dental caries: more than mechanical retention
Wen, Z. T., Huang, X., Ellepola, K., Liao, S., & Li, Y. (2022) · Microbiology · doi:10.1099/mic.0.001196 · Cited by 61 · see citing works
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Arnold, J. W., Simpson, J. B., Roach, J. M., Bruno-Bárcena, J. M., & Azcárate-Peril, M. A. (2018) · Nutrients · doi:10.3390/nu10101517 · Cited by 59 · see citing works
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Vuong, H. Q., & McFrederick, Q. S. (2019) · Genome Biology and Evolution · doi:10.1093/gbe/evz136 · Cited by 58 · see citing works
Starter cultures as a reservoir of antibiotic resistant microorganisms
Zarzecka, U., Zadernowska, A., & Chajęcka‐Wierzchowska, W. (2020) · LWT · doi:10.1016/j.lwt.2020.109424 · Cited by 58 · see citing works
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Iorizzo, M., Lombardi, S. J., Ganassi, S., Testa, B., Ianiro, M., Letizia, F., Succi, M., Tremonte, P., Vergalito, F., Cozzolino, A., et al. (2020) · Antibiotics · doi:10.3390/antibiotics9050262 · Cited by 57 · see citing works
Global transcriptomic analysis of Lactobacillus plantarum CAUH2 in response to hydrogen peroxide stress
Zhai, Z., Yang, Y., Wang, H., Wang, G., Ren, F., Li, Z., & Hao, Y. (2019) · Food Microbiology · doi:10.1016/j.fm.2019.103389 · Cited by 56 · see citing works
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Idrees, M., Imran, M., Atiq, N., Zahra, R., Abid, R., Alreshidi, M. M., Roberts, T. K., Abdelgadir, A., Tipu, M. K., Farid, A., et al. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.959941 · Cited by 56 · see citing works
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Cao, F., Jin, L., Zhang, C., Gao, Y., Qian, Z., Wen, H., Yang, S., Ye, Z., Hong, L., Huang, Y., et al. (2023) · Advanced Materials · doi:10.1002/adma.202304257 · Cited by 56 · see citing works
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Filannino, P., Angelis, M. D., Cagno, R. D., Gozzi, G., Riciputi, Y., & Gobbetti, M. (2018) · Environmental Microbiology · doi:10.1111/1462-2920.14372 · Cited by 56 · see citing works
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Yang, X., Teng, K., Zhang, J., Wang, F., Zhang, T., Ai, G., Han, P., Bai, F., & Zhong, J. (2017) · Scientific Reports · doi:10.1038/s41598-017-02975-8 · Cited by 53 · see citing works
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Chan, M. Z. A., Toh, M., & Liu, S. (2021) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2021.109229 · Cited by 52 · see citing works
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Kathiriya, M. R., Vekariya, Y. V., & Hati, S. (2023) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-023-10104-3 · Cited by 50 · see citing works
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Wu, H., Liu, J., Miao, S., Zhao, Y., Zhu, H., Qiao, M., Saris, P. E. J., & Qiao, J. (2018) · Applied and Environmental Microbiology · doi:10.1128/aem.02483-17 · Cited by 50 · see citing works
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Demir, Y., Dikbaş, N., & Beydemir, Ş. (2018) · Molecular Biotechnology · doi:10.1007/s12033-018-0116-1 · Cited by 50 · see citing works
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Zhang, G., Tu, J., Sadiq, F. A., Zhang, W., & Wang, W. (2019) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12459 · Cited by 50 · see citing works
Impact of Freezing and Freeze Drying on Lactobacillus rhamnosus GG Survival: Mechanisms of Cell Damage and the Role of Pre-Freezing Conditions and Cryoprotectants
Wang, J., Wu, P., Dhital, S., Yu, A., & Chen, X. D. (2025) · Foods · doi:10.3390/foods14101817 · Cited by 49 · see citing works
Enhanced Acid Tolerance in Lactobacillus acidophilus by Atmospheric and Room Temperature Plasma (ARTP) Coupled with Adaptive Laboratory Evolution (ALE)
Nyabako, B. A., Fang, H., Cui, F., Liu, K., Tao, T.-L., Zan, X., & Sun, W. (2020) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-020-03264-3 · Cited by 49 · see citing works

Stress responses in lactic acid bacteria
van de Guchte, M., Serror, P., Chervaux, C., Smokvina, T., Ehrlich, S. D., & Maguin, E. (2002) · Antonie van Leeuwenhoek · doi:10.1023/a:1020631532202 · Cited by 648 · see citing works
Strategies to enhance stress tolerance in lactic acid bacteria across diverse stress conditions
Derunets, A. S., Selimzyanova, A. I., Rykov, S. V., Kuznetsov, A. Y., & Berezina, O. V. (2024) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-024-03905-3 · Cited by 73 · see citing works
The Importance of Understanding the Stress Physiology of Lactic Acid Bacteria
Franz, C. M. A. P., & Holzapfel, W. H. (2011) · Springer eBooks · doi:10.1007/978-0-387-92771-8_1 · Cited by 14 · see citing works
Stress Responses of LAB
Longo, A., & Spano, G. (2019) · CRC Press eBooks · doi:10.1201/9781315110110-9 · Cited by 2 · see citing works
Cross protection of lactic acid bacteria during environmental stresses: Stress responses and underlying mechanisms
Yang, H., He, M., & Wu, C. (2021) · LWT · doi:10.1016/j.lwt.2021.111203 · Cited by 129 · see citing works

Authors: Papadimitriou, K., Alegría, Á., Bron, P. A., de Angelis, M., Gobbetti, M., Kleerebezem, M., Lemos, J. A., Linares, D. M., Ross, P., Stanton, C., Turroni, F., van Sinderen, D., Varmanen, P., Ventura, M., Zúñiga, M., Tsakalidou, E., & Kok, J.
Affiliations: Agricultural University of Athens (GR)
University of Groningen (NL)
TiFN (NL)
Department of Soil, Plant and Food Sciences, University of Bari Aldo Moro, Bari, Italy
University of Bari Aldo Moro (IT)
Department of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA
Teagasc - The Irish Agriculture and Food Development Authority (IE)
APC, Microbiome Institute, University College Cork, Cork, Ireland
University of Parma (IT)
University of Helsinki (FI)
Consejo Superior de Investigaciones Científicas (ES)
ORCID: Papadimitriou, Konstantinos
Alegría, Ángel
Bron, Peter A.
Gobbetti, Marco
Kleerebezem, Michiel
Stanton, Catherine
Turroni, Francesca
Varmanen, Pekka
Ventura, Marco
Zúñiga, Manuel
Tsakalidou, Effie
Kok, Jan
Venue: Microbiology and Molecular Biology Reviews
Publisher: American Society for Microbiology
Published: 2016-09
Volume: 80
Issue: 3
Pages: 837-890
ISSN: 1092-2172 (ISSN-L)
1098-5557
DOI: 10.1128/mmbr.00076-15
PMC: PMC4981675
OpenAlex: W2499564842
Cited by: 914
References: 646
Citations by year: 2026: 173 · 2025: 163 · 2024: 97 · 2023: 92 · 2022: 86 · 2021: 92 · 2020: 83 · 2019: 56 · 2018: 48 · 2017: 20 · 2016: 3
FWCI: 4.84
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Microbiology and Molecular Biology Reviews (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Socio-Environmental Systems Modeling (acceptedVersion)
CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro) (submittedVersion, cc-by-nc-nd)
University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, other-oa)
Open Research (University of Surrey) (submittedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion)
Funders: European Commission (2007–2013, FP7 2007-2013, FP7/2007, 623448)
Science Foundation Ireland (13/IA/1953, 12/RC/2273, 12/RC/)
APC Microbiome Institute
National Institute of Dental and Craniofacial Research (DE019783, DE022559, R01DE019783, R01DE022559)
Topics: Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Microbial Inactivation Methods
Keywords: lactic acid bacteria, stress physiology, stress response, probiotics, Lactobacillus, Lactococcus lactis, Enterococcus, Streptococcus, stress tolerance, biofilm, dormancy, prophage induction, stress tolerance engineering, food industry
MeSH terms: Energy Metabolism, Fermentation, Food Microbiology, Lactobacillus, Osmotic Pressure, Streptococcus, Stress, Physiological, Signal Transduction, Enterococcus, Biofilms, Lactic Acid, Probiotics

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