Associations Between ADHD and Psychoactive Substance use Disorders:Findings from a Longitudinal Study of High-Risk Siblings of ADHD Children
Open accessAbstract
This article investigates the relationship between attention-deficit/hyperactivity disorder (ADHD) and psychoactive substance use disorders (PSUD) in siblings of ADHD and normal-control probands and addresses issues of psychiatric comorbidity and gender. Using DSM-III-R structured diagnostic interviews and blind raters, the authors conducted a 4-year follow-up of siblings. ADHD and male gender predicted higher rates and an earlier onset of PSUD after adjusting for high-risk status, other psychiatric disorders, and age. Risk was particularly high if the siblings had ADHD plus conduct disorder. This study's findings confirms the authors' prior report high-lighting the importance of drug and alcohol prevention and cessation programs aimed at ADHD youth and their siblings, particularly those with comorbid conduct disorder.
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Childhood attention deficit hyperactivity disorder is significantly associated with adolescent and adult substance use disorders.
“Numerous studies have shown that childhood attention deficit hyperactivity disorder (ADHD) is significantly associated with adolescent and adult substance use disorders (SUD) (1–8).”
From Age of methylphenidate treatment initiation in children with ADHD and later substance abuse: prospective follow-up into adulthood. (2008) · cites this paper as [7]
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- Authors
- Milberger, S., Biederman, J., Faraone, S. V., Wilens, T., & Chu, M. P.
- Affiliations
- Harvard University (US)
- Venue
- American Journal on Addictions
- Publisher
- Wiley
- Published
- 1997-01
- Volume
- 6
- Issue
- 4
- Pages
- 318-329
- ISSN
- 1055-0496 (ISSN-L)
- 1521-0391
- OpenAlex
- W2033897832
- Cited by
- 113
- References
- 3
- Citations by year
- 2021: 1 · 2019: 2 · 2018: 1 · 2017: 2 · 2015: 3 · 2014: 7 · 2013: 9 · 2012: 8
- FWCI
- 2.01
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- American Journal on Addictions (publishedVersion)
- PubMed (publishedVersion)
- SUNY Digital Repository Support (State University of New York System) (submittedVersion, cc-by-nc-nd)
- Funders
- National Institutes of Health (5k01da000294-02, 2r01mh041314-04)
- National Institute of Mental Health (R01 MH41314-07)
- National Institute on Drug Abuse (1 K01 DA00294-01)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- attention deficit hyperactivity disorder, psychoactive substance use disorders, psychiatric comorbidity, gender differences, conduct disorder, substance use onset, at-risk youth
- MeSH terms
- Adolescent, Attention Deficit Disorder with Hyperactivity, Child Behavior Disorders, Female, Follow-Up Studies, Humans, Male, Psychiatric Status Rating Scales, Psychotropic Drugs, Risk Factors, Sex Factors, Illicit Drugs, Comorbidity, Substance-Related Disorders, Alcohol-Related Disorders
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