The DOI matches its Crossref record; 70 of the 70 references it cites were found in a registry or an index.
The potential of lipocalin-2/NGAL as biomarker for inflammatory and metabolic diseases
Open accessAbstract
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a secreted glycoprotein that belongs to a group of transporters of small lipophilic molecules in circulation. LCN2 has been recently characterized as an adipose-derived cytokine. This adipokine is believed to bind small substances, such as steroids and lipopolysaccharides, and has been reported to have roles in the induction of apoptosis in hematopoietic cells, transport of fatty acids and iron, modulation of inflammation, and metabolic homeostasis. Recently, LCN2 has emerged as a useful biomarker and rheumatic diseases. This review provides an overview of LCN2 in inflammation, immunity, and metabolism.
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Cites
Inflammatory Mechanisms in Obesity
Gregor, M. F., & Hotamisligil, G. S. (2011) · Annual Review of Immunology · doi:10.1146/annurev-immunol-031210-101322 · Cited by 3,754
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
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A Cell-Surface Receptor for Lipocalin 24p3 Selectively Mediates Apoptosis and Iron Uptake
Devireddy, L. R., Gazin, C., Zhu, X., & Green, M. R. (2005) · Cell · doi:10.1016/j.cell.2005.10.027 · Cited by 672
An Iron Delivery Pathway Mediated by a Lipocalin
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Cowland, J. B., & Borregaard, N. (1997) · Genomics · doi:10.1006/geno.1997.4896 · Cited by 619
Neutrophil Gelatinase–Associated Lipocalin (NGAL) as a Marker of Kidney Damage
Bolignano, D., Donato, V., Coppolino, G., Campo, S., Buemi, A., Lacquaniti, A., & Buemi, M. (2008) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2008.01.020 · Cited by 581
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Adipokines as emerging mediators of immune response and inflammation
Lago, F., Dieguez, C., Gómez-Reino, J., & Gualillo, O. (2007) · Nature Clinical Practice Rheumatology · doi:10.1038/ncprheum0674 · Cited by 567
Self-citationChassaing, B., Srinivasan, G., Delgado, M. A., Young, A. N., Gewirtz, A. T., & Vijay-Kumar, M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044328 · Cited by 554
Cited by
Sabat, R., Jemec, G. B. E., Matusiak, Ł., Kimball, A. B., Prens, E., & Wolk, K. (2020) · Nature Reviews Disease Primers · doi:10.1038/s41572-020-0149-1 · Cited by 573
A new immunometabolic perspective of intervertebral disc degeneration
Francisco, V., Pino, J., González-Gay, M. Á., Lago, F., Karppinen, J., Tervonen, O., Mobasheri, A., & Gualillo, O. (2022) · Nature Reviews Rheumatology · doi:10.1038/s41584-021-00713-z · Cited by 462
Self-citationLipocalin 2: an emerging player in iron homeostasis and inflammation
Xiao, X., Yeoh, B. S., & Vijay-Kumar, M. (2017) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-071816-064559 · Cited by 426
Lipocalin-2: A Master Mediator of Intestinal and Metabolic Inflammation
Moschen, A. R., Adolph, T. E., Gerner, R. R., Wieser, V., & Tilg, H. (2017) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2017.01.003 · Cited by 359
Guerrero‐Hue, M., García‐Caballero, C., Palomino‐Antolín, A., Rubio‐Navarro, A., Vázquez‐Carballo, C., Herencia, C., Martín‐Sanchez, D., Farré‐Alins, V., Egea, J., Cannata, P., et al. (2019) · The FASEB Journal · doi:10.1096/fj.201900077r · Cited by 268
Metadata
- Authors
- Abella, V., Scotece, M., Conde, J., Gómez, R., Lois, A., Pino, J., Gómez-Reino, J. J., Lago, F., Mobasheri, A., & Gualillo, O.
- Venue
- Biomarkers
- Publisher
- Informa UK Limited
- Published
- 2015-11-17
- Volume
- 20
- Issue
- 8
- Pages
- 565-571
- ISSN
- 1354-750X (ISSN-L)
- 1366-5804
- OpenAlex
- W2215409508
- Cited by
- 288
- References
- 70
- FWCI
- 10.55
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Abella, V., Scotece, M., Conde, J., Gómez, R., Lois, A., Pino, J., Gómez-Reino, J. J., Lago, F., Mobasheri, A., & Gualillo, O. (2015). The potential of lipocalin-2/NGAL as biomarker for inflammatory and metabolic diseases. Biomarkers. https://doi.org/10.3109/1354750x.2015.1123354
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