The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.
Medicinal significance of benzothiazole scaffold: an insight view
Abstract
Heterocycles bearing nitrogen, sulphur and thiazole moieties constitute the core structure of a number of biologically interesting compounds. Benzothiazole, a group of xenobiotic compounds containing a benzene ring fused with a thiazole ring, are used worldwide for a variety of therapeutic applications. Benzothiazole and their heterocyclic derivatives represent an important class of compounds possessing a wide spectrum of biological activities. The myriad spectrum of medicinal properties associated with benzothiazole related drugs has encouraged the medicinal chemists to synthesize a large number of novel therapeutic agents. Several analogues containing benzothiazole ring system exhibit significant antitumour, antimicrobial, antidiabetic, anti-inflammatory, anticonvulsant, antiviral, antioxidant, antitubercular, antimalarial, antiasthmatic, anthelmintic, photosensitizing, diuretic, analgesic and other activities. This article is an attempt to present the research work reported in recent scientific literature on different pharmacological activities of benzothiazole compounds.
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Citations
Cites
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Carbonic anhydrases as targets for medicinal chemistry
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Ciprofloxacin: review on developments in synthetic, analytical, and medicinal aspects
Sharma, P. C., Jain, A., Jain, S., Pahwa, R., & Yar, M. S. (2010) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.3109/14756360903373350 · Cited by 353
Self-citationSynthesis and anticancer evaluation of bis(benzimidazoles), bis(benzoxazoles), and benzothiazoles
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Cited by
Keri, R. S., Patil, M. R., Patil, S. A., & Budagumpi, S. (2015) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2014.10.059 · Cited by 631
Thiazole-containing compounds as therapeutic targets for cancer therapy
Sharma, P. C., Bansal, K. K., Sharma, A., Sharma, D., & Deep, A. (2020) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2019.112016 · Cited by 382
Self-citationElectroorganic Synthesis under Flow Conditions
Elsherbini, M., & Wirth, T. (2019) · Accounts of Chemical Research · doi:10.1021/acs.accounts.9b00497 · Cited by 303
Metadata
- Authors
- Sharma, P. C., Sinhmar, A., Sharma, A., Rajak, H., & Pathak, D. P.
- Venue
- Journal of Enzyme Inhibition and Medicinal Chemistry
- Publisher
- Informa UK Limited
- Published
- 2012-10-03
- Volume
- 28
- Issue
- 2
- Pages
- 240-266
- ISSN
- 1475-6366 (ISSN-L)
- 1475-6374
- OpenAlex
- W2095300431
- Cited by
- 256
- References
- 60
- FWCI
- 1.90
- Type
- journal article
- Language
- en
- Open access
- closed
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- Sharma, P. C., Sinhmar, A., Sharma, A., Rajak, H., & Pathak, D. P. (2013). Medicinal significance of benzothiazole scaffold: an insight view. Journal of Enzyme Inhibition and Medicinal Chemistry. https://doi.org/10.3109/14756366.2012.720572
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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