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Cited by 353

The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.

Ciprofloxacin: review on developments in synthetic, analytical, and medicinal aspects

Open access
Sharma, Prabodh Chander, Jain, Ankit, Jain, Sandeep, Pahwa, Rakesh, Yar, Mohammad Shahar·2010·Journal of Enzyme Inhibition and Medicinal Chemistry

Abstract

In the current practices of anti-infective therapy, ciprofloxacin is a very popular fluoroquinolone having a broad spectrum of activity and diverse therapeutic prospects. The reasons for its wide use include multiresistant pathogens susceptible only to ciprofloxacin. The available clinical evidence suggests the potentially enhanced efficacy of this drug in the treatment of various community acquired and nosocomial infections, e.g. respiratory tract, urinary tract, and skin infections and sexually transmitted diseases. As compared to other agents of its class, the pharmacokinetic profile of ciprofloxacin demonstrates equivalent or greater bioavailability, higher plasma concentrations, and increased tissue penetration, as reflected in the greater volume of distribution. Various molecular modifications of this drug have been made to further improve its characteristics. Several methods of analytical determination of ciprofloxacin and its metabolites in biological fluids employing various techniques have been reported. The present article is focused on the synthetic development, pharmacotherapeutic, and analytical evaluation vistas of ciprofloxacin.

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Metadata

Authors
Sharma, P. C., Jain, A., Jain, S., Pahwa, R., & Yar, M. S.
Venue
Journal of Enzyme Inhibition and Medicinal Chemistry
Published
2010-03-17
Volume
25
Issue
4
Pages
577-589
ISSN
  • 1475-6366 (ISSN-L)
  • 1475-6374
OpenAlex
W2139554217
Cited by
353
References
49
FWCI
6.80
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Ciprofloxacin: review on developments in synthetic, analytical, and medicinal aspects. https://app.cochat.ai/papers/10.3109/14756360903373350
The paper
Sharma, P. C., Jain, A., Jain, S., Pahwa, R., & Yar, M. S. (2010). Ciprofloxacin: review on developments in synthetic, analytical, and medicinal aspects. Journal of Enzyme Inhibition and Medicinal Chemistry. https://doi.org/10.3109/14756360903373350

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.