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PreprintCited by 226Mindfulness and Compassion InterventionsStress Responses and CortisolDigital Mental Health Interventions

The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.

Acceptance lowers stress reactivity: Dismantling mindfulness training in a randomized controlled trial

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Lindsay, Emily K, Young, Shinzen, Smyth, Joshua M, Brown, Kirk Warren, Creswell, J. David·2017·Psychoneuroendocrinology
DOI 10.31219/osf.io/4se5m

Preprint — published as 10.1016/j.psyneuen.2017.09.015 · Paper page

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Abstract

Objective: Mindfulness interventions, which train practitioners to monitor their present-moment experience with a lens of acceptance, are known to buffer stress reactivity. Little is known about the active mechanisms driving these effects. We theorize that acceptance is a critical emotion regulation mechanism underlying mindfulness stress reduction effects. Method: In this three-arm parallel trial, mindfulness components were dismantled into three structurally equivalent 15-lesson smartphone-based interventions: (1) training in both monitoring and acceptance (Monitor+Accept), (2) training in monitoring only (Monitor Only), or (3) active control training (Coping control). 153 stressed adults (mean age = 32 years; 67% female; 53% white, 21.5% black, 21.5% Asian, 4% other race) were randomly assigned to complete one of three interventions. After the intervention, cortisol, blood pressure, and subjective stress reactivity were assessed using a modified Trier Social Stress Test. Results: As predicted, Monitor+Accept training reduced cortisol and systolic blood pressure reactivity compared to Monitor Only and control trainings. Participants in all three conditions reported moderate levels of subjective stress.Conclusions: This study provides the first experimental evidence that brief smartphone mindfulness training can impact stress biology, and that acceptance training drives these effects. We discuss implications for basic and applied research in contemplative science, emotion regulation, stress and coping, health, and clinical interventions.

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Metadata

Authors
Lindsay, E. K., Young, S., Smyth, J. M., Brown, K. W., & Creswell, J. D.
Affiliations
  • Carnegie Mellon University (US)
  • University of Vermont (US)
  • Pennsylvania State University (US)
  • Virginia Commonwealth University (US)
Corresponding author
Lindsay, Emily K
ORCID
Venue
Psychoneuroendocrinology
Publisher
Center for Open Science
Published
2017-09-28
Volume
87
Pages
63-73
ISSN
0306-4530 (ISSN-L)
DOI
10.31219/osf.io/4se5m
OpenAlex
W2764264186
Cited by
226
References
64
Citations by year
2026: 17 · 2025: 33 · 2024: 28 · 2023: 24 · 2022: 31 · 2021: 28 · 2020: 30 · 2019: 21 · 2018: 12 · 2017: 2
FWCI
22.05
Type
journal article
Language
en
Open access
Licence
Locations
  • Psychoneuroendocrinology (publishedVersion)
  • PubMed (publishedVersion)
  • OSF Preprints (OSF Preprints) (submittedVersion, cc-by)
  • MindRxiv (OSF Preprints) (submittedVersion)
  • MindRxiv (OSF Preprints) (submittedVersion, cc-by)
  • OSF Preprints (OSF Preprints) (submittedVersion)
Funders
  • American Psychological Association
  • Mind and Life Institute
  • National Institutes of Health (UL1TR000005)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
Keywords
mindfulness training, acceptance, stress reactivity, emotion regulation, cortisol, blood pressure, smartphone-based intervention, Trier Social Stress Test, stress biology, coping, contemplative science
MeSH terms
Smartphone, Adaptation, Psychological, Adult, Emotions, Female, Humans, Hydrocortisone, Male, Psychological Distance, Stress, Psychological, Meditation, Mindfulness

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