PreprintCited by 14Ethics and Social Impacts of AIArtificial Intelligence in Healthcare and EducationDigital Mental Health Interventions

Delusions by design? How everyday AIs might be fuelling psychosis (and what can be done about it)

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Morrin, Hamilton, Nicholls, Luke, Levin, Michael, Yiend, Jenny, Iyengar, Udita, DelGuidice, Francesca, Bhattacharyya, Sagnik, MacCabe, James +4 more·2025

Abstract

Large language models (LLMs) are poised to become a ubiquitous feature of our lives, mediating communication, decision-making and information curation across nearly every domain. Within psychiatry and psychology the focus to date has remained largely on bespoke therapeutic applications, sometimes narrowly focused and often diagnostically siloed, rather than on the broader and more pressing reality that individuals with mental illness will increasingly engage in agential interactions with AI systems as a routine part of daily existence. While their capacity to model therapeutic dialogue, provide 24/7 companionship and assist with cognitive support has sparked understandable enthusiasm, recent reports suggest that these same systems may contribute to the onset or exacerbation of psychotic symptoms: so-called ‘AI psychosis’ or ‘ChatGPT psychosis’. Emerging, and rapidly accumulating, evidence indicates that agential AI may mirror, validate or amplify delusional or grandiose content, particularly in users already vulnerable to psychosis, due in part to the models’ design to maximise engagement and affirmation, although notably it is not clear whether these interactions have resulted or can result in the emergence of de novo psychosis in the absence of pre-existing vulnerability. Even if some individuals may benefit from AI interactions, for example where the AI functions as a benign and predictable conversational anchor, there is a growing concern that these agents may also reinforce epistemic instability, blur reality boundaries and disrupt self-regulation. In this paper, we outline both the potential harms and therapeutic possibilities of agential AI for people with psychotic disorders. In this perspective piece, we propose a framework of AI-integrated care involving personalised instruction protocols, reflective check-ins, digital advance statements and escalation safeguards to support epistemic security in vulnerable users. These tools reframe the AI agent as an epistemic ally (as opposed to ‘only’ a therapist or a friend) which functions as a partner in relapse prevention and cognitive containment. Given the rapid adoption of LLMs across all domains of digital life, these protocols must be urgently trialled and co-designed with service users and clinicians.

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  • An AI that consistently mirrors user affect or beliefs, without implementing therapeutic disconfirmation or cognitive restructuring, risks entrenching conviction rather than facilitating doubt.

    “an AI that consistently mirrors user affect or beliefs, without implementing therapeutic disconfirmation or cognitive restructuring, risks entrenching conviction rather than facilitating doubt [28].”

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Authors
Morrin, H., Nicholls, L., Levin, M., Yiend, J., Iyengar, U., DelGuidice, F., Bhattacharyya, S., MacCabe, J., Tognin, S., Twumasi, R., Alderson-Day, B., & Pollak, T.
Affiliations
  • King's College London (GB)
  • The Graduate Center, CUNY (US)
  • Tufts University (US)
Published
2025-08-22
OpenAlex
W4413427926
Cited by
14
References
7
Citations by year
2026: 10 · 2025: 4
Type
posted content
Language
en
Open access
Topics
  • Social Sciences › Safety Research › Ethics and Social Impacts of AI
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
Keywords
AI psychosis, large language models, psychosis, delusions, grandiosity, epistemic instability, relapse prevention, epistemic security, AI companionship

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