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Cited by 465

The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.

Pharmaceutical significance of cellulose: A review

Open access
Kamel, S., Ali, N., Jahangir, K., Shah, S. M., El-Gendy, A. A.·2008·Express Polymer Letters
DOI 10.3144/expresspolymlett.2008.90
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Abstract

The amalgamation of polymer and pharmaceutical sciences led to the introduction of polymer in the design and development of drug delivery systems.Polymeric delivery systems are mainly intended to achieve controlled or sustained drug delivery.Polysaccharides fabricated into hydrophilic matrices remain popular biomaterials for controlled-release dosage forms and the most abundant naturally occurring biopolymer is cellulose; so hdroxypropylmethyl cellulose, hydroxypropyl cellulose, microcrystalline cellulose and hydroxyethyl cellulose can be used for production of time controlled delivery systems.Additionally microcrystalline cellulose, sodium carboxymethyl cellulose, hydroxypropylmethyl cellulose, hydroxyethyl cellulose as well as hydroxypropyl cellulose are used to coat tablets.Cellulose acetate phthalate and hydroxymethyl cellulose phthalate are also used for enteric coating of tablets.Targeting of drugs to the colon following oral administration has also been accomplished by using polysaccharides such as hdroxypropylmethyl cellulose and hydroxypropyl cellulose in hydrated form; also they act as binders that swell when hydrated by gastric media and delay absorption.This paper assembles the current knowledge on the structure and chemistry of cellulose, and in the development of innovative cellulose esters and ethers for pharmaceuticals.

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Metadata

Authors
Kamel, S., Ali, N., Jahangir, K., Shah, S. M., & El-Gendy, A. A.
Venue
Express Polymer Letters
Publisher
Department of Polymer Engineering, Scientific Society of Mechanical Engineering
Published
2008
Volume
2
Issue
11
Pages
758-778
ISSN
1788-618X (ISSN-L)
DOI
10.3144/expresspolymlett.2008.90
OpenAlex
W2032732763
Cited by
465
References
74
FWCI
6.07
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Pharmaceutical significance of cellulose: A review. https://app.cochat.ai/papers/10.3144/expresspolymlett.2008.90
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Kamel, S., Ali, N., Jahangir, K., Shah, S. M., & El-Gendy, A. A. (2008). Pharmaceutical significance of cellulose: A review. Express Polymer Letters. https://doi.org/10.3144/expresspolymlett.2008.90

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.