Evaluation of resources for analyzing drug interactions
Open accessAbstract
Objective The research sought to evaluate seven drug information resources, specifically designed for analyzing drug interactions for scope, completeness, and ease of use, and determine the consistency of content among the seven resources. Methods A cross-sectional study was conducted where 100 drug-drug and drug-dietary supplement interactions were analyzed using 7 drug information resources: Lexicomp Interactions module, Micromedex Drug Interactions, Clinical Pharmacology Drug Interaction Report, Facts & Comparisons eAnswers, Stockley's Drug Interactions (10th edition), Drug Interactions Analysis and Management (2014), and Drug Interaction Facts (2015). The interaction sample was developed based on published resources and peer input. Two independent reviewers gathered data for each interaction from each of the 7 resources using a common form. Results Eighty-two drug-drug and 18 drug-dietary supplement interactions were analyzed. Scope scores were higher for Lexicomp Interactions (97.0%), Clinical Pharmacology Drug Interaction Report (97.0%), and Micromedex Drug Interactions (93.0%) compared to all other resources ( p p p p Conclusions Clinical Pharmacology Drug Interaction Report, Lexicomp Interactions, and Micromedex Drug Interactions scored highest in scope. Micromedex Drug Interactions and Lexicomp Interactions scored highest in completeness. Consistency scores were overall low, but Micromedex Drug Interactions was the highest.
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When additional information was needed, panel members could consult three drug interaction compendia, Lexicomp, Micromedex and Stockley's Drug Interactions, as supporting knowledge sources.
“When additional information was needed, panel members could consult three drug interaction compendia (Lexicomp, Micromedex and Stockley's Drug Interactions) as supporting knowledge sources [37,38].”
From Comparing Artificial Intelligence (ChatGPT, Gemini, DeepSeek) and Oral Surgeons in Detecting Clinically Relevant Drug–Drug Interactions in Dental Therapy (2025) · cites this paper as [38]
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- Authors
- Patel, R. I., & Beckett, R. D.
- Affiliations
- University of Arizona (US)
- University of Manchester (GB)
- ORCID
- Beckett, Robert D.
- Venue
- Journal of the Medical Library Association : JMLA
- Published
- 2016-10
- Volume
- 104
- Issue
- 4
- Pages
- 290-295
- ISSN
- 1536-5050 (ISSN-L)
- 1558-9439
- PMC
- PMC5079490
- OpenAlex
- W2551182653
- Cited by
- 97
- References
- 11
- Citations by year
- 2026: 7 · 2025: 8 · 2024: 6 · 2023: 18 · 2022: 7 · 2021: 13 · 2020: 17 · 2019: 11 · 2018: 6 · 2017: 4
- FWCI
- 8.80
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by
- Locations
- Journal of the Medical Library Association JMLA (publishedVersion, cc-by)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- UA Campus Repository (The University of Arizona) (acceptedVersion, cc-by)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacy and Medical Practices
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
- Keywords
- drug interactions, drug information resources, drug-drug interactions, information resource evaluation, content consistency, completeness, ease of use
- MeSH terms
- Drug Information Services, Drug Interactions, Humans, Reference Books, Databases, Factual
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