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Cited by 585

The DOI matches its Crossref record; 177 of the 177 references it cites were found in a registry or an index.

Cerebral circulation and metabolism

Siesjö, Bo K.·1984·Journal of Neurosurgery

Abstract

✓ Recent developments in the field of cerebral circulation and metabolism are reviewed, with emphasis on circulatory and metabolic events that have a bearing on brain damage incurred in ischemia. The first part of the treatise reviews aspects of cerebral metabolism that provide a link to the coupling of metabolism and blood flow, notably those that lead to a perturbation of cellular energy state, ionic homeostasis, and phospholipid metabolism. In the second part, attention is focused on the derangement of energy metabolism and its effects on ion fluxes, acid-base homeostasis, and lipid metabolism. It is emphasized that gross brain damage, involving edema formation and infarction, is enhanced by tissue acidosis, and that neuronal damage, often showing a pronounced selectivity in localization, appears related to a disturbed Ca 2+ homeostasis, and to Ca 2+-triggered events such as lipolysis and proteolysis.

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Crossref · 10.3171/jns.1984.60.5.0883

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Metadata

Authors
Siesjö, B. K.
Venue
Journal of Neurosurgery
Published
1984-05
Volume
60
Issue
5
Pages
883-908
ISSN
0022-3085 (ISSN-L)
OpenAlex
W1987939219
Cited by
585
References
177
FWCI
35.39
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Cerebral circulation and metabolism. https://app.cochat.ai/papers/10.3171/jns.1984.60.5.0883
The paper
Siesjö, B. K. (1984). Cerebral circulation and metabolism. Journal of Neurosurgery. https://doi.org/10.3171/jns.1984.60.5.0883

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.