The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
High-dose barbiturate control of elevated intracranial pressure in patients with severe head injury
Abstract
✓ In a five-center study, 73 patients with severe head injury and elevated intracranial pressure (ICP) were randomly assigned to receive either a regimen that included high-dose pentobarbital or one that was otherwise similar but did not include pentobarbital. The results indicated a 2:1 benefit for those treated with the drug with regard to ICP control. When patients were stratified by prerandomization cardiac complications, the advantage increased to 4:1. A multiple logistic model considering treatment and selected baseline variables indicated a significant positive treatment effect of barbiturates, a significant effect of time from injury to randomization, and an interaction of treatment with cardiovascular complications. However, of 925 patients potentially eligible for randomization, only 12% met ICP randomization criteria. The results support the hypothesis that high-dose pentobarbital is an effective adjunctive therapy, but that it is indicated in only a small subset of patients with severe head injury.
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Self-citationThe National Traumatic Coma Data Bank: Part 1: Design, purpose, goals, and results
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Self-citationEarly Insults to the Injured Brain
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Lack of Effect of Induction of Hypothermia after Acute Brain Injury
Clifton, G. L., Miller, E. R., Choi, S. C., Levin, H. S., McCauley, S., Smith, K. R., Muizelaar, J. P., Wagner, F. C., Marion, D. W., Luerssen, T. G., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200102223440803 · Cited by 1,382
Cerebral perfusion pressure: management protocol and clinical results
Rosner, M. J., Rosner, S. D., & Johnson, A. H. (1995) · Journal of Neurosurgery · doi:10.3171/jns.1995.83.6.0949 · Cited by 963
Outcome following decompressive craniectomy for malignant swelling due to severe head injury
Aarabi, B., Hesdorffer, D. C., Ahn, E. S., Aresco, C., Scalea, T. M., & Eisenberg, H. M. (2006) · Journal of Neurosurgery · doi:10.3171/jns.2006.104.4.469 · Cited by 615
Self-citationVI. Indications for Intracranial Pressure Monitoring
Bratton, S. L., Chestnut, R. M., Ghajar, J., McConnell Hammond, F. F., Harris, O. A., Hartl, R., Manley, G. T., Nemecek, A., Newell, D. W., Rosenthal, G., et al. (2007) · Journal of Neurotrauma · doi:10.1089/neu.2007.9990 · Cited by 405
Guidelines for Prehospital Management of Traumatic Brain Injury 2nd Edition
Badjatia, N., Carney, N., Crocco, T. J., Fallat, M. E., Hennes, H. M. A., Jagoda, A. S., Jernigan, S., Letarte, P. B., Lerner, E. B., Moriarty, T. M., et al. (2008) · Prehospital Emergency Care · doi:10.1080/10903120701732052 · Cited by 368
Metadata
- Authors
- Eisenberg, H. M., Frankowski, R. F., Contant, C. F., Marshall, L. F., Walker, M. D., & _, _.
- Venue
- Journal of Neurosurgery
- Published
- 1988-07
- Volume
- 69
- Issue
- 1
- Pages
- 15-23
- ISSN
- 0022-3085 (ISSN-L)
- OpenAlex
- W1966212698
- Cited by
- 593
- References
- 18
- FWCI
- 10.57
- Type
- journal article
- Language
- en
- Open access
- closed
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- Eisenberg, H. M., Frankowski, R. F., Contant, C. F., Marshall, L. F., Walker, M. D., & _, _. (1988). High-dose barbiturate control of elevated intracranial pressure in patients with severe head injury. Journal of Neurosurgery. https://doi.org/10.3171/jns.1988.69.1.0015
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
