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Total removal of craniopharyngiomas: Approaches and long-term results in 144 patients
Abstract
✓ The clinical features, perioperative course, and postoperative outcomes of 144 patients who underwent microsurgical resection of craniopharyngioma were reviewed. Overall, 90% of the tumors were completely resected and 7% recurred. Evaluation of those patients who underwent primary resection revealed much better results. The operative techniques and approaches are reviewed in detail. The results of this series suggest that primary total removal of craniopharyngiomas yields the best long-term outcome for the patient. Experience has shown that the larger the tumor the greater will be the damage, both preoperatively and intraoperatively, to vital intracranial structures. Consequently, early diagnosis, at a stage when the tumor is still small, improves the chances of accomplishing complete removal and of achieving good operative results. The early diagnosis of craniopharyngioma, before it can produce devastating neurological defects, continues to be the principal goal of our medical and pediatric colleagues.
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Citations
Cited by
Craniopharyngiomas in children and adults: systematic analysis of 121 cases with long-term follow-up
Karavitaki, N., Brufani, C., Warner, J. T., Adams, C. B. T., Richards, P., Ansorge, O., Shine, B., Turner, H. E., & Wass, J. A. H. (2005) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2005.02231.x · Cited by 633
Aggressive surgical management of craniopharyngiomas in children
Hoffman, H. J., Silva, M. D., Humphreys, R. P., Drake, J. M., Smith, M. L., & Blaser, S. I. (1992) · Journal of Neurosurgery · doi:10.3171/jns.1992.76.1.0047 · Cited by 567
Karavitaki, N., Cudlip, S., Adams, C. B. T., & Wass, J. A. H. (2006) · Endocrine Reviews · doi:10.1210/er.2006-0002 · Cited by 514
Mortality in Patients with Pituitary Disease
Sherlock, M., Ayuk, J., Tomlinson, J. W., Toogood, A. A., Aragon-Alonso, A., Sheppard, M. C., Bates, A. S., & Stewart, P. M. (2010) · Endocrine Reviews · doi:10.1210/er.2009-0033 · Cited by 392
Management of childhood craniopharyngioma: can the morbidity of radical surgery be predicted?
De Vile, C. J., Grant, D. B., Kendall, B. E., Neville, B. G. R., Stanhope, R., Watkins, K. E., & Hayward, R. D. (1996) · Journal of Neurosurgery · doi:10.3171/jns.1996.85.1.0073 · Cited by 331
Metadata
- Authors
- Yaşargil, M. G., Curcic, M., Kis, M., Siegenthaler, G., Teddy, P. J., & Roth, P.
- Venue
- Journal of Neurosurgery
- Published
- 1990-07
- Volume
- 73
- Issue
- 1
- Pages
- 3-11
- ISSN
- 0022-3085 (ISSN-L)
- OpenAlex
- W1928904918
- Cited by
- 817
- References
- 0
- FWCI
- 8.06
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yaşargil, M. G., Curcic, M., Kis, M., Siegenthaler, G., Teddy, P. J., & Roth, P. (1990). Total removal of craniopharyngiomas: Approaches and long-term results in 144 patients. Journal of Neurosurgery. https://doi.org/10.3171/jns.1990.73.1.0003
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