The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Management of childhood craniopharyngioma: can the morbidity of radical surgery be predicted?
Abstract
✓ Seventy-five children treated for craniopharyngioma between 1973 and 1994 were studied to demonstrate which pre- and intraoperative factors were indicative of a poor outcome as defined by a quantitative assessment of morbidity. This involved a retrospective review of 65 patients and a prospective study of 10 patients focused on clinical details and cranial imaging and a follow-up “study assessment” of 66 survivors performed over the last 2 years. As part of the assessment, 63 patients underwent magnetic resonance imaging with a three-dimensional volume acquisition sequence 1.5 to 19.2 years after initial surgery. Predictors of high morbidity included severe hydrocephalus, intraoperative adverse events, and young age (≤ 5 years) at presentation. Predictors of increased hypothalamic morbidity included symptoms of hypothalamic disturbance already established at diagnosis, greater height (≥ 3.5 cm) of the tumor in the midline, and attempts to remove adherent tumor from the region of the hypothalamus at operation. Large tumor size, young age, and severe hydrocephalus were predictors of tumor recurrence, whereas complete tumor resection (as determined by postoperative neuroimaging) and radiotherapy given electively after subtotal excision were less likely to be associated with recurrent disease. Based on these findings, the authors propose an individualized, more flexible treatment approach whereby surgical strategies may be modified to provide long-term tumor control with the lowest morbidity.
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Cites
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Total removal of craniopharyngiomas: Approaches and long-term results in 144 patients
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Craniopharyngioma — long-term results following limited surgery and radiotherapy
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Management of Craniopharyngioma in Childhood
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Cited by
Craniopharyngiomas in children and adults: systematic analysis of 121 cases with long-term follow-up
Karavitaki, N., Brufani, C., Warner, J. T., Adams, C. B. T., Richards, P., Ansorge, O., Shine, B., Turner, H. E., & Wass, J. A. H. (2005) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2005.02231.x · Cited by 633
Karavitaki, N., Cudlip, S., Adams, C. B. T., & Wass, J. A. H. (2006) · Endocrine Reviews · doi:10.1210/er.2006-0002 · Cited by 514
Mortality in Patients with Pituitary Disease
Sherlock, M., Ayuk, J., Tomlinson, J. W., Toogood, A. A., Aragon-Alonso, A., Sheppard, M. C., Bates, A. S., & Stewart, P. M. (2010) · Endocrine Reviews · doi:10.1210/er.2009-0033 · Cited by 392
Crabtree, V. M., Klages, K. L., Sykes, A., Wise, M. S., Lu, Z., Indelicato, D., Merchant, T. E., Avent, Y., & Mandrell, B. N. (2019) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.7982 · Cited by 27
Klages, K. L., Berlin, K. S., Cook, J. L., Merchant, T. E., Wise, M. S., Mandrell, B. N., Conklin, H. M., & Crabtree, V. M. (2022) · Psycho-Oncology · doi:10.1002/pon.5862 · Cited by 25
Metadata
- Authors
- De Vile, C. J., Grant, D. B., Kendall, B. E., Neville, B. G. R., Stanhope, R., Watkins, K. E., & Hayward, R. D.
- Venue
- Journal of Neurosurgery
- Published
- 1996-07
- Volume
- 85
- Issue
- 1
- Pages
- 73-81
- ISSN
- 0022-3085 (ISSN-L)
- OpenAlex
- W2158599331
- Cited by
- 331
- References
- 28
- FWCI
- 3.94
- Type
- journal article
- Language
- en
- Open access
- closed
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- De Vile, C. J., Grant, D. B., Kendall, B. E., Neville, B. G. R., Stanhope, R., Watkins, K. E., & Hayward, R. D. (1996). Management of childhood craniopharyngioma: can the morbidity of radical surgery be predicted? Journal of Neurosurgery. https://doi.org/10.3171/jns.1996.85.1.0073
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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