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Cited by 426

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Natural history of intracranial cavernous malformations

Aiba, Toyotaka, Tanaka, Ryuichi, Koike, Tetsuo, Kameyama, Shigeki, Takeda, Norio, Komata, Tadashi·1995·Journal of Neurosurgery

Abstract

✓ The authors have reviewed the clinical records of 110 patients with intracranial cavernous malformations diagnosed by histological examination and/or magnetic resonance imaging over a mean follow-up period of 4.71 years. These cases were divided, based on their presentation, into a hemorrhage group, a seizure group, and an incidentally diagnosed group. The rate of subsequent symptomatic bleeding was investigated in relation to age at onset, sex, and location of the initial lesion. A high rate of subsequent symptomatic bleeding episodes was found in the hemorrhage group, especially among younger females. The nonhemorrhagic-onset cases had a very low incidence of bleeding. The outcome was generally good, except in patients with lesions in the basal ganglia and brainstem. These findings will be helpful in planning a rational therapeutic strategy for intracranial cavernous malformations.

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Metadata

Authors
Aiba, T., Tanaka, R., Koike, T., Kameyama, S., Takeda, N., & Komata, T.
Venue
Journal of Neurosurgery
Published
1995-07
Volume
83
Issue
1
Pages
56-59
ISSN
0022-3085 (ISSN-L)
OpenAlex
W2002659392
Cited by
426
References
0
FWCI
5.51
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Natural history of intracranial cavernous malformations. https://app.cochat.ai/papers/10.3171/jns.1995.83.1.0056
The paper
Aiba, T., Tanaka, R., Koike, T., Kameyama, S., Takeda, N., & Komata, T. (1995). Natural history of intracranial cavernous malformations. Journal of Neurosurgery. https://doi.org/10.3171/jns.1995.83.1.0056

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.