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Detection of Cryptococcus neoformans Antigen in Body Fluids by Latex Particle Agglutination.
Abstract
Antigen of C. neoformans was detected in serum and/or CSF from 7 of 9 cases of CNS cryptococcosis by a rapid, sensitive slide test in which antibody-coated latex particles are agglutinated. The procedure yielded few nonspecific reactions, which were of low degree. Decline in reactivity following treatment suggests that the test has prognostic as well as diagnostic value. Lack of reactivity of blood and CSF from 2 patients was shown not to be attributable to serotype variation.
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Citations
Cited by
Cryptococcosis in the era of AIDS--100 years after the discovery of Cryptococcus neoformans
Mitchell, T. G., & Perfect, J. R. (1995) · Clinical Microbiology Reviews · doi:10.1128/cmr.8.4.515 · Cited by 1,213
Maziarz, E. K., & Perfect, J. R. (2016) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2015.10.006 · Cited by 698
Cryptococcal infections in patients with acquired immune deficiency syndrome
Eng, R. H. K., Bishburg, E., Smith, S. M., & Kapila, R. (1986) · The American Journal of Medicine · doi:10.1016/0002-9343(86)90176-2 · Cited by 317
Protective murine monoclonal antibodies to Cryptococcus neoformans
Mukherjee, J., Scharff, M. D., & Casadevall, A. (1992) · Infection and Immunity · doi:10.1128/iai.60.11.4534-4541.1992 · Cited by 282
Hansen, J., Slechta, E. S., Gates-Hollingsworth, M. A., Neary, B., Barker, A. P., Bauman, S., Kozel, T. R., & Hanson, K. E. (2013) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00536-12 · Cited by 130
Metadata
- Authors
- Bloomfield, N., Gordon, M. A., & Elmendorf, D. F.
- Venue
- Experimental Biology and Medicine
- Publisher
- Frontiers Media SA
- Published
- 1963-10-01
- Volume
- 114
- Issue
- 1
- Pages
- 64-67
- ISSN
- 0071-3384 (ISSN-L)
- 1535-3702
- 1535-3699
- OpenAlex
- W2043458690
- Cited by
- 221
- References
- 0
- FWCI
- 2.61
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Detection of Cryptococcus neoformans Antigen in Body Fluids by Latex Particle Agglutination. https://app.cochat.ai/papers/10.3181/00379727-114-28586
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- Bloomfield, N., Gordon, M. A., & Elmendorf, D. F. (1963). Detection of Cryptococcus neoformans Antigen in Body Fluids by Latex Particle Agglutination. Experimental Biology and Medicine. https://doi.org/10.3181/00379727-114-28586
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
