The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.
Protective murine monoclonal antibodies to Cryptococcus neoformans
Open accessAbstract
Several murine monoclonal antibodies (MAbs) specific for the capsular glucuronoxylomannan of Cryptococcus neoformans were studied for their capacity to confer protection when passively administered to lethally infected mice. The MAb group studied recognized at least three distinct epitopes and included immunoglobulin M (IgM), IgG3, IgG1, and IgA isotypes. The protection model used A/J and BALB/c mice infected intraperitoneally with 10(8) cryptococci. The MAbs were administered either immediately preceding or, in one experiment, 24 to 48 h prior to infection. Protective efficacy was assessed by the ability of passively administered MAbs to prolong the survival of lethally infected mice. Three IgM MAbs, each of which recognized a distinct epitope, were able to prolong survival of lethally infected mice to different extents. A set of IgM, IgG3, IgG1 and IgA MAbs which utilize the same immunoglobulin gene elements and were derived from the same B-cell clone exhibited significant class differences in protective efficacy with IgA, IgG1 > IgM > IgG3. The results confirm that protective MAbs against C. neoformans capsular polysaccharide exist and strongly suggest that both epitope specificity and isotype are important determinants of protective efficacy.
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Cites
Infections with Cryptococcus neoformans in the Acquired Immunodeficiency Syndrome
Chuck, S. L., & Sande, M. A. (1989) · New England Journal of Medicine · doi:10.1056/nejm198909213211205 · Cited by 797
Prognostic Factors in Cryptococcal Meningitis: A Study in 111 Cases
DIAMOND, R. D., & BENNETT, J. E. (1974) · Annals of Internal Medicine · doi:10.7326/0003-4819-80-2-176 · Cited by 605
Biological Activities of Immunoglobulins of Different Classes and Subclasses
Spiegelberg, H. L. (1974) · Advances in Immunology · doi:10.1016/s0065-2776(08)60254-0 · Cited by 496
Immunoglobulin A: Strategic Defense Initiative at the Mucosal Surface
Underdown, B. (1986) · Annual Review of Immunology · doi:10.1146/annurev.immunol.4.1.389 · Cited by 414
Cryptococcal infections in patients with acquired immune deficiency syndrome
Eng, R. H. K., Bishburg, E., Smith, S. M., & Kapila, R. (1986) · The American Journal of Medicine · doi:10.1016/0002-9343(86)90176-2 · Cited by 317
Binding of monomeric immunoglobulins to Fc receptors of mouse macrophages.
Unkeless, J. C., & Eisen, H. N. (1975) · The Journal of experimental medicine · doi:10.1084/jem.142.6.1520 · Cited by 317
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Dromer, F., Charreire, J., Contrepois, A., Carbon, C., & Yeni, P. (1987) · Infection and Immunity · doi:10.1128/iai.55.3.749-752.1987 · Cited by 243
Detection of Cryptococcus neoformans Antigen in Body Fluids by Latex Particle Agglutination.
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Casadevall, A., Mukherjee, J., Devi, S. J. N., Schneerson, R., Robbins, J. B., & Scharff, M. D. (1992) · The Journal of Infectious Diseases · doi:10.1093/infdis/165.6.1086 · Cited by 210
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Cited by
An insight into the antifungal pipeline: selected new molecules and beyond
Ostrosky-Zeichner, L., Casadevall, A., Galgiani, J. N., Odds, F. C., & Rex, J. H. (2010) · Nature Reviews Drug Discovery · doi:10.1038/nrd3074 · Cited by 432
Self-citationPerfect, J. R., & Casadevall, A. (2002) · Infectious Disease Clinics of North America · doi:10.1016/s0891-5520(02)00036-3 · Cited by 363
Self-citationPolysaccharide antigens of the capsule of Cryptococcus neoformans
Cherniak, R., & Sundstrom, J. B. (1994) · Infection and Immunity · doi:10.1128/iai.62.5.1507-1512.1994 · Cited by 320
Casadevall, A., Cleare, W., Feldmesser, M., Glatman-Freedman, A., Goldman, D. L., Kozel, T. R., Lendvai, N., Mukherjee, J., Pirofski, L.-A., Rivera, J., et al. (1998) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.42.6.1437 · Cited by 298
Self-citationLarsen, R. A., Pappas, P. G., Perfect, J., Aberg, J. A., Casadevall, A., Cloud, G. A., James, R., Filler, S., & Dismukes, W. E. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.3.952-958.2005 · Cited by 236
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Metadata
- Authors
- Mukherjee, J., Scharff, M. D., & Casadevall, A.
- Venue
- Infection and Immunity
- Publisher
- American Society for Microbiology
- Published
- 1992-11
- Volume
- 60
- Issue
- 11
- Pages
- 4534-4541
- ISSN
- 0019-9567 (ISSN-L)
- 1098-5522
- OpenAlex
- W1712993486
- Cited by
- 282
- References
- 50
- FWCI
- 9.74
- Type
- journal article
- Language
- en
- Open access
- green
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- Mukherjee, J., Scharff, M. D., & Casadevall, A. (1992). Protective murine monoclonal antibodies to Cryptococcus neoformans. Infection and Immunity. https://doi.org/10.1128/iai.60.11.4534-4541.1992
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
