The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Bacterial Vaccines and Serotype Replacement: Lessons from Haemophilus influenzae and Prospects for Streptococcus pneumoniae
Open accessAbstract
Conjugate vaccines have reduced the incidence of invasive disease caused by Haemophilus influenzae, type b (Hib), in industrialized countries and may be highly effective against Streptococcus pneumoniae. However, the serotype specificity of these vaccines has led to concern that their use may increase carriage of and disease from serotypes not included in the vaccine. Replacement has not occurred with the use of Hib vaccines but has occurred in trials of pneumococcal vaccines. Mathematical models can be used to elucidate these contrasting outcomes, predict the conditions under which serotype replacement is likely, interpret the results of conjugate vaccine trials, design trials that will better detect serotype replacement (if it occurs), and suggest factors to consider in choosing the serotype composition of vaccines.
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Citations
Cites
Decline of Childhood Haemophilus influenzae Type b (Hib) Disease in the Hib Vaccine Era
Adams, W. G. (1993) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1993.03500020055031 · Cited by 696
Cited by
Serotype replacement in disease after pneumococcal vaccination
Weinberger, D. M., Malley, R., & Lipsitch, M. (2011) · The Lancet · doi:10.1016/s0140-6736(10)62225-8 · Cited by 1,020
Self-citationThe Ecology of Genetically Diverse Infections
Read, A. F., & Taylor, L. H. (2001) · Science · doi:10.1126/science.1059410 · Cited by 639
Metadata
- Authors
- Lipsitch, M.
- Venue
- Emerging Infectious Diseases
- Published
- 1999-06
- Volume
- 5
- Issue
- 3
- Pages
- 336-345
- ISSN
- 1080-6040 (ISSN-L)
- 1080-6059
- OpenAlex
- W2014942315
- Cited by
- 286
- References
- 1
- FWCI
- 10.97
- Type
- journal article
- Language
- en
- Open access
- diamond
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- CoChat. (2026). Citation check: Bacterial Vaccines and Serotype Replacement: Lessons from Haemophilus influenzae and Prospects for Streptococcus pneumoniae. https://app.cochat.ai/papers/10.3201/eid0503.990304
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- Lipsitch, M. (1999). Bacterial Vaccines and Serotype Replacement: Lessons from Haemophilus influenzae and Prospects for Streptococcus pneumoniae. Emerging Infectious Diseases. https://doi.org/10.3201/eid0503.990304
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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