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Cited by 314

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Experimental Infection of Horses with West Nile virus

Open access
Bunning, Michel L., Bowen, Richard A., Cropp, Bruce C., Sullivan, Kevin G., Davis, Brent S., Komar, Nieholas, Godsey, Marvin, Baker, Dale, Hettler, Danielle L., Holmes, Derek A., Biggerstaff, Brad J., Mitchell, Carl J.·2002·Emerging Infectious Diseases

Abstract

A total of 12 horses of different breeds and ages were infected with West Nile virus (WNV) via the bites of infected Aedes albopictus mosquitoes. Half the horses were infected with a viral isolate from the brain of a horse (BC787), and half were infected with an isolate from crow brain (NY99-6625); both were NY99 isolates. Postinfection, uninfected female Ae. albopictus fed on eight of the infected horses. In the first trial, Nt antibody titers reached >1:320, 1:20, 1:160, and 1:80 for horses 1 to 4, respectively. In the second trial, the seven horses with subclinical infections developed Nt antibody titers >1:10 between days 7 and 11 post infection. The highest viremia level in horses fed upon by the recipient mosquitoes was approximately 460 Vero cell PFU/mL. All mosquitoes that fed upon viremic horses were negative for the virus. Horses infected with the NY99 strain of WNV develop low viremia levels of short duration; therefore, infected horses are unlikely to serve as important amplifying hosts for WNV in nature.

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Crossref · 10.3201/eid0804.010239

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Metadata

Authors
Bunning, M. L., Bowen, R. A., Cropp, B. C., Sullivan, K. G., Davis, B. S., Komar, N., Godsey, M., Baker, D., Hettler, D. L., Holmes, D. A., Biggerstaff, B. J., & Mitchell, C. J.
Venue
Emerging Infectious Diseases
Published
2002-04
Volume
8
Issue
4
Pages
380-386
ISSN
  • 1080-6040 (ISSN-L)
  • 1080-6059
OpenAlex
W2088899348
Cited by
314
References
1
FWCI
19.33
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Experimental Infection of Horses with West Nile virus. https://app.cochat.ai/papers/10.3201/eid0804.010239
The paper
Bunning, M. L., Bowen, R. A., Cropp, B. C., Sullivan, K. G., Davis, B. S., Komar, N., Godsey, M., Baker, D., Hettler, D. L., Holmes, D. A., Biggerstaff, B. J., & Mitchell, C. J. (2002). Experimental Infection of Horses with West Nile virus. Emerging Infectious Diseases. https://doi.org/10.3201/eid0804.010239

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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