The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Toxoplasma gondii and Schizophrenia
Open accessAbstract
Recent epidemiologic studies indicate that infectious agents may contribute to some cases of schizophrenia. In animals, infections with Toxoplasma gondii can alter behavior and neurotransmitter function. In humans, acute infection with T. gondii can produce psychotic symptoms similar to those displayed by persons with schizophrenia. Since 1953, a total of 19 studies of T. gondii antibodies in persons with schizophrenia and other severe psychiatric disorders and in controls have been reported; 18 reported a higher percentage of antibodies in the affected persons; in 11 studies the difference was statistically significant. Two other studies found that exposure to cats in childhood was a risk factor for the development of schizophrenia. Some medications used to treat schizophrenia inhibit the replication of T. gondii in cell culture. Establishing the role of T. gondii in the etiopathogenesis of schizophrenia might lead to new medications for its prevention and treatment.
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Cites
Toxoplasma gondii: from animals to humans
Tenter, A. M., Heckeroth, A. R., & Weiss, L. M. (2000) · International Journal for Parasitology · doi:10.1016/s0020-7519(00)00124-7 · Cited by 3,702
Cognitive Impairment in Schizophrenia Is the Core of the Disorder
Elvevag, B., & Goldberg, T. E. (2000) · Critical Reviews™ in Neurobiology · doi:10.1615/critrevneurobiol.v14.i1.10 · Cited by 835 · cited 1×
“Hydrocephalus (7), increased ventricular size (8), and cognitive impairment (9) have also been noted in some persons with schizophrenia and other forms of psychosis.”
BackgroundFatal attraction in rats infected with Toxoplasma gondii
Berdoy, M., Webster, J. P., & Macdonald, D. W. (2000) · Proceedings of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rspb.2000.1182 · Cited by 734
Glial cell abnormalities in major psychiatric disorders: the evidence and implications
Cotter, D. R., Pariante, C. M., & Everall, I. P. (2001) · Brain Research Bulletin · doi:10.1016/s0361-9230(01)00527-5 · Cited by 465
Retroviral RNA identified in the cerebrospinal fluids and brains of individuals with schizophrenia
Karlsson, H., Bachmann, S., Schröder, J., McArthur, J., Torrey, E. F., & Yolken, R. H. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.061021998 · Cited by 378
Self-citationRantakallio, P., Jones, P., Moring, J., & Von Wendt, L. (1997) · International Journal of Epidemiology · doi:10.1093/ije/26.4.837 · Cited by 276
Jones-Brando, L. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(02)00357-2 · Cited by 243
Decrease of psychomotor performance in subjects with latent ‘asymptomatic’ toxoplasmosis
HAVLÍČEK, J., GAšOVÁ, Z., SMITH, A. P., ZVÁRA, K., & FLEGR, J. (2001) · Parasitology · doi:10.1017/s0031182001007624 · Cited by 238
Antibodies to infectious agents in individuals with recent onset schizophrenia
Leweke, F. M., Gerth, C. W., Koethe, D., Klosterk�tter, J., Ruslanova, I., Krivogorsky, B., Torrey, E. F., & Yolken, R. H. (2004) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-004-0481-6 · Cited by 226
Self-citationAntibodies to Toxoplasma gondii in Individuals with First-Episode Schizophrenia
Yolken, R. H., Bachmann, S., Rouslanova, I., Lillehoj, E., Ford, G., Torrey, E. F., & Schroeder, J. (2001) · Clinical Infectious Diseases · doi:10.1086/319221 · Cited by 159
Self-citation
Cited by
Antibodies to Toxoplasma gondii in Patients With Schizophrenia: A Meta-Analysis
Torrey, E. F., Bartko, J. J., Lun, Z.-R., & Yolken, R. H. (2007) · Schizophrenia Bulletin · doi:10.1093/schbul/sbl050 · Cited by 503
Self-citationToxoplasma Effectors Targeting Host Signaling and Transcription
Hakimi, M.-A., Olias, P., & Sibley, L. D. (2017) · Clinical Microbiology Reviews · doi:10.1128/cmr.00005-17 · Cited by 339
Epidemiology of Schizophrenia: Review of Findings and Myths
Messias, E. L., Chen, C.-Y., & Eaton, W. W. (2007) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2007.04.007 · Cited by 310
Cross talk: the microbiota and neurodevelopmental disorders
Kelly, J. R., Minuto, C., Cryan, J. F., Clarke, G., & Dinan, T. G. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00490 · Cited by 271
Pedersen, C. B., & Mortensen, P. B. (2006) · American Journal of Epidemiology · doi:10.1093/aje/kwj169 · Cited by 79
Metadata
- Authors
- Torrey, E. F., & Yolken, R. H.
- Venue
- Emerging Infectious Diseases
- Published
- 2003-11
- Volume
- 9
- Issue
- 11
- Pages
- 1375-1380
- ISSN
- 1080-6040 (ISSN-L)
- 1080-6059
- OpenAlex
- W2116888044
- Cited by
- 331
- References
- 23
- FWCI
- 8.45
- Type
- journal article
- Language
- en
- Open access
- diamond
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
