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Cited by 411

The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.

Antigenic and Genetic Variability of Human Metapneumoviruses

Open access
van den Hoogen, Bernadette G., Herfst, Sander, Sprong, Leo, Cane, Patricia A., Forleo-Neto, Eduardo, de Swart, Rik L., Osterhaus, Albert D.M.E., Fouchier, Ron A.M.·2004·Emerging Infectious Diseases

Abstract

Human metapneumovirus (HMPV) is a member of the subfamily Pneumovirinae within the family Paramyxo- viridae. Other members of this subfamily, respiratory syncytial virus and avian pneumovirus, can be divided into subgroups on the basis of genetic or antigenic differences or both. For HMPV, the existence of different genetic lineages has been described on the basis of variation in a limited set of available sequences. We address the antigenic relationship between genetic lineages in virus neutralization assays. In addition, we analyzed the genetic diversity of HMPV by phylogenetic analysis of sequences obtained for part of the fusion protein (n = 84) and the complete attachment protein open reading frames (n = 35). On the basis of sequence diversity between attachment protein genes and the differences in virus neutralization titers, two HMPV serotypes were defined. Each serotype could be divided into two genetic lineages, but these did not reflect major antigenic differences.

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Metadata

Authors
van den Hoogen, B. G., Herfst, S., Sprong, L., Cane, P. A., Forleo-Neto, E., de Swart, R. L., Osterhaus, A. D. M. E., & Fouchier, R. A. M.
Venue
Emerging Infectious Diseases
Published
2004-04
Volume
10
Issue
4
Pages
658-666
ISSN
  • 1080-6040 (ISSN-L)
  • 1080-6059
OpenAlex
W2114064040
Cited by
411
References
33
FWCI
20.48
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Antigenic and Genetic Variability of Human Metapneumoviruses. https://app.cochat.ai/papers/10.3201/eid1004.030393
The paper
van den Hoogen, B. G., Herfst, S., Sprong, L., Cane, P. A., Forleo-Neto, E., de Swart, R. L., Osterhaus, A. D. M. E., & Fouchier, R. A. M. (2004). Antigenic and Genetic Variability of Human Metapneumoviruses. Emerging Infectious Diseases. https://doi.org/10.3201/eid1004.030393

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.