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Clostridium difficile Infections among Hospitalized Children, United States, 1997–2006
Open accessAbstract
We evaluated the annual rate (cases/10,000 hospitalizations) of pediatric hospitalizations with Clostridium difficile infection (CDI; International Classification of Diseases, 9th revision, clinical modification code 008.45) in the United States. We performed a time-series analysis of data from the Kids' Inpatient Database within the Health Care Cost and Utilization Project during 1997-2006 and a cross-sectional analysis within the National Hospital Discharge Survey during 2006. The rate of pediatric CDI-related hospitalizations increased from 7.24 to 12.80 from 1997 through 2006; the lowest rate was for children <1 year of age. Although incidence was lowest for newborns (0.5), incidence for children <1 year of age who were not newborns (32.01) was similar to that for children 5-9 years of age (35.27), which in turn was second only to incidence for children 1-4 years of age (44.87). Pediatric CDI-related hospitalizations are increasing. A better understanding of the epidemiology and outcomes of CDI is urgently needed.
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Cited by
McDonald, L. C., Gerding, D. N., Johnson, S., Bakken, J. S., Carroll, K. C., Coffin, S. E., Dubberke, E. R., Garey, K. W., Gould, C. V., Kelly, C., et al. (2018) · Clinical Infectious Diseases · doi:10.1093/cid/cix1085 · Cited by 2,690
Self-citationHamilton, M. J., Weingarden, A. R., Sadowsky, M. J., & Khoruts, A. (2012) · American Journal of Gastroenterology · doi:10.1038/ajg.2011.482 · Cited by 738
Carey-Ann, B. D., & Carroll, K. C. (2013) · Clinical Microbiology Reviews · doi:10.1128/cmr.00016-13 · Cited by 423
Global burden of Clostridium difficile infections: a systematic review and meta-analysis
Balsells, E., Shi, T., Leese, C., Lyell, I., Burrows, J., Wiuff, C., Campbell, H., Kyaw, M. H., & Nair, H. (2019) · Journal of Global Health · doi:10.7189/jogh.09.010407 · Cited by 309
Prevalence of Healthcare-Associated Infections in Acute Care Hospitals in Jacksonville, Florida
Magill, S. S., Hellinger, W., Cohen, J., Kay, R., Bailey, C., Boland, B., Carey, D., Guzman, J. D., Dominguez, K., Edwards, J., et al. (2012) · Infection Control & Hospital Epidemiology · doi:10.1086/664048 · Cited by 295
Metadata
- Authors
- Zilberberg, M. D., Tillotson, G. S., & McDonald, L. C.
- Venue
- Emerging Infectious Diseases
- Published
- 2010-04
- Volume
- 16
- Issue
- 4
- Pages
- 604-609
- ISSN
- 1080-6040 (ISSN-L)
- 1080-6059
- OpenAlex
- W2170693496
- Cited by
- 240
- References
- 0
- FWCI
- 16.14
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Zilberberg, M. D., Tillotson, G. S., & McDonald, L. C. (2010). Clostridium difficile Infections among Hospitalized Children, United States, 1997–2006. Emerging Infectious Diseases. https://doi.org/10.3201/eid1604.090680
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