Gene Dosage Dependent Aggravation of the Neurological Phenotype in the 5XFAD Mouse Model of Alzheimer’s Disease

Cited by (136)

Items 101–136 of 136

1. Ginsenoside Rg1 Ameliorates the Learning and Memory Deficits of 5xFAD Mice by Inhibiting CCR3 Activity: Insights from In Vivo and In Vitro Investigations
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2. Early disruptions in brain capillary blood flow control in a mouse model of Alzheimer’s disease
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3. Resistance of E2F4DN to p38MAPK phosphorylation reduces genotoxic cell death in N2a neuron-like cells
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4. Integrated Cross-Disease Atlas of Human And Mouse Astrocytes Reveals Heterogeneity and Conservation of Astrocyte Subtypes in Neurodegeneration
   Tawaun A. Lucas, Gloriia Novikova, Sadhna Rao, Yuanyuan Wang, Benjamin I. Laufer, Shristi Pandey, Michelle G. Webb, Nikolas L. Jorstad, Brad A. Friedman, Jesse E. Hanson et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
5. Amyloid beta 4-42 in Alzheimer’s disease: Target, Therapy, Mechanism
   Gregory Antonios · 2016 · eDiss (Georg-August-Universität Göttingen)
6. Quantitative analysis of neuropathological alterations in two transgenic mouse models of Alzheimer's disease
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7. In Vitro and In Vivo Studies on Antibodies - N-terminally Truncated Abeta in the 5XFAD Mouse Model
   Bernhard Clemens Richard · 2015 · eDiss (Georg-August-Universität Göttingen)
8. Divergence in Neuronal Calcium Dysregulation in Brain Aging and Animal Models of AD
   Adam O. Ghoweri · 2020 · UKnowledge (University of Kentucky)
9. Kif11 overexpression rescues cognition, long-term potentiation, and spine defects in mouse and cell models of Alzheimer’s disease
   Esteban Lucero, Ronald K. Freund, Noah R. Johnson, Breanna R. Dooling, Emily M. Sullivan, Olga Prikhodko, Md. Mahiuddin Ahmed, Mark L. Dell’Acqua, Heidi J. Chial, Huntington Potter · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
10. Exploring sphingolipid function in the pathogenesis of Alzheimer’s disease
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11. The role of N-truncated Aβ peptides in Alzheimer’s Disease
    José Sócrates López‐Noguerola · 2018 · eDiss (Georg-August-Universität Göttingen)
12. Der Einfluss von (-)-Δ9-trans- Tetrahydrocannabinol und Cannabidiol auf die Alzheimer-Pathologie im 5XFAD-Mausmodell
    Eva Maria Schleicher · 2021 · eDiss (Georg-August-Universität Göttingen)
13. N-truncated Aβ4-x peptides in Alzheimer's disease: generation, degradation, and relationship with neuropathological hallmarks
    Silvia Zampar · 2021 · eDiss (Georg-August-Universität Göttingen)
14. Faculty Opinions recommendation of Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease.
    Guillermo C. Oliver, Xiaolei Liu · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
15. Amyloid-β Clearance and its Evaluation by Auditory Stimulation in a Mouse Model of Alzheimer's Disease
    Maika Ogawa, Yasue Mitsukura, Yoichiro Abe, Masato Yasui · 2022 · Annual Conference of the IEEE Industrial Electronics Society (IECON)
16. Der Einfluss von Cannabidiol auf die Alzheimer Pathologie im 5xFAD Mausmodell in einem präventiven Behandlungsansatz
    Nina Horkulak · 2023 · eDiss (Georg-August-Universität Göttingen)
17. Modified Investigation Tools and Techniques Useful in Alzheimer’s Disease Research
    Sharada Laxman Deore, Bhushan Arun Baviskar, Anjali Ashokrao Kide, Somshekhar S. Khadabadi, Bhavana Ashok Shende · 2023 · Springer eBooks
18. Changes in the Activity and Content of Individual Forms of Proteasomes in Samples of the Cerebral Cortex during Pathology Development in 5xFAD Mice
    А. V. Morozov, Alexander V. Burov, S. Yu. Funikov, Ekaterina V. Teterina, Tatiana M. Astakhova, Pavel A. Erokhov, A. A. Ustyugov, В. Л. Карпов · 2023 · Molecular Biology
19. Neuronal expression of E2F4DN restores adult neurogenesis in homozygous 5xFAD mice via TrkB signaling
    Anna Lozano-Ureña, Aina M. Llabrés-Mas, Morgan Ramón‐Landreau, Alberto Fraj, Cristina Sánchez‐Puelles, Alberto Garrido‐García, Vanesa Cano‐Daganzo, Lorena Valdés-Lora, José María Frade · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
20. Animal Models and Ethics in the Testing of Drugs for Alzheimer’s Disease
    Parikshit Roychowdhury, Antony Justin, Mirunalini Gobinath, Veera Venkata Satyanarayana Reddy Karri, Gowthamarajan Kuppusamy · 2024 · Springer eBooks
21. The Christchurch point mutation in mouse APOE reduces Aβ-induced tau and α-synuclein pathologies
    Carlos M. Soto-Faguás, Abigail O’Niel, Paul A. Mueller, Paula Sanchez-Molina, Randy L Woltjer, Jacob Raber, Vivek K. Unni · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
22. Additional file 1 of MMP9 modulation improves specific neurobehavioral deficits in a mouse model of Alzheimer’s disease
    Charis Ringland, Jonas Elias Schweig, Eisenbaum, Maxwell, Daniel Paris, Ghania Ait‐Ghezala, Mullan, Michael, Fiona Crawford, Laila I. Abdullah, Bachmeier, Corbin · 2021 · Figshare
23. Additional file 2 of CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer’s disease
    Simone M. Crivelli, Qian Luo, Jo Stevens, Caterina Giovagnoni, Daan van Kruining, Gerard H. Bode, Sandra den Hoedt, Barbara Hobo, Scheithauer, Anna-Lena, Walter, Jochen et al. · 2021 · Figshare
24. Additional file 1 of Microglial amyloid beta clearance is driven by PIEZO1 channels
    Henna Jäntti, Valeriia Sitnikova, Yevheniia Ishchenko, Anastasia Shakirzyanova, Luca Giudice, Ugidos, Irene F., Mireia Gómez‐Budia, Nea Korvenlaita, Sohvi Ohtonen, Irina Belaya et al. · 2022 · Figshare
25. Additional file 1 of CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer’s disease
    Simone M. Crivelli, Qian Luo, Jo Stevens, Caterina Giovagnoni, Daan van Kruining, Gerard H. Bode, Sandra den Hoedt, Barbara Hobo, Scheithauer, Anna-Lena, Walter, Jochen et al. · 2021 · Figshare
26. Additional file 3 of CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer’s disease
    Simone M. Crivelli, Qian Luo, Jo Stevens, Caterina Giovagnoni, Daan van Kruining, Gerard H. Bode, Sandra den Hoedt, Barbara Hobo, Scheithauer, Anna-Lena, Jochen Walter et al. · 2021 · Figshare
27. Mouse models of Alzheimer’s disease pathology
    Sunwoo Kim, Nora E. Gray · 2025 · Elsevier eBooks
28. Structural and ultrastructural organization of the parietal cortex and dorsal hippocampus in transgenic 5xFAD mice administered sodium valproate, a histone deacetylase inhibitor
    Natalia L. Tumanova, D. S. Vasilev, Nadezhda M. Dubrovskaya, Natalia N. Nalivaeva · 2025 · Veterinary Science Development
29. Pharmacological targeting of the integrated stress response by 2BAct improves object recognition memory and reduces neuroinflammation in the 5xFAD model of Alzheimer's disease
    D H Kim, Hojung Jeong, Hye Kyung Lim, Soo Min Ahn, Minseok Song · 2026 · Journal of Alzheimer s Disease
30. In vivo evidence for soluble Aβ oligomer-driven neuronal metabolic dysfunction in 5xFAD mice
    Chaynita Dashora, Anant Bahadur Patel · 2026 · Alzheimer s Research & Therapy
31. Pre-plaque glutamatergic hyperexcitability, mitochondrial dysfunction, and dendritic remodeling in the hippocampus of one-month-old 5xFAD mice
    Amanda Kelley, Emily Denise Sackinger, Mathew Frischman, Nicholas O. Thomas, Kaitlyn Kim, Grace Scuderi, Edwin M. Labut, Duncan MacMurchy, Toren Ikea-Mario, Jacob Rauenhorst et al. · 2026 · Frontiers in Aging Neuroscience
32. Effects of in vitro Embryo Culturing and Subsequent Embryo Transfer on Behavior and Brain Development in 5xFAD Mice: a Model of Alzheimer’s Disease
    I. N. Rozhkova, Е. Ю. Брусенцев, V. S. Kozeneva, T. A. Rakhmanova, I D Chekashov, S. S. Solovieva, S. V. Okotrub, S. I. Chulkova, Sergei Ya Amstislavsky · 2026 · Journal of Evolutionary Biochemistry and Physiology
33. Gene therapy in Alzheimer’s disease (AD)
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34. The influence of mutant genes APP and PSEN1 on hippocampal asymmetry in 5xFAD mice, transgenic model of Alzheimer disease
    Eugeny Yu. Brusentsev, И. Н. Рожкова, V. S. Kozeneva, I D Chekashov, T. A. Rakhmanova, Oleg B. Shevelev, Sergei Ya Amstislavsky · 2026 · Vavilov Journal of Genetics and Breeding
35. Use of animal models to understand CNS neuroimmunology — guidance from the International Society for Neuroimmunology White Paper Task Force
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36. Communication breakdown: Impaired pericyte KATP channels in a model of Alzheimer’s disease
    William F. Jackson · 2026 · The Journal of General Physiology