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Cited by 68Alzheimer's disease research and treatmentsCholesterol and Lipid MetabolismNeuroinflammation and Neurodegeneration Mechanisms

RETRACTED: Potential Mechanisms Linking Cholesterol to Alzheimer's Disease-like Pathology in Rabbit Brain, Hippocampal Organotypic Slices, and Skeletal Muscle

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Ghribi, Othman·2008·Journal of Alzheimer's Disease
DOI 10.3233/jad-2008-15412PMC PMC2805037
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Abstract

This article has been retracted, and the online PDF has been watermarked “RETRACTED”. A retraction notice is available at DOI: 10.3233/JAD-239016.

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  • Diets with increased cholesterol increase tau phosphorylation in wild-type and human tau transgenic mammals.

    “Reports in both wild-type and in human tau transgenic mammals indicate that diets with increased cholesterol do indeed increase tau phosphorylation (265–267).”

    From Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation (2011) · cites this paper as [265]

    The “Cholesterol and Tau Phosphorylation” section reports that a cholesterol-enriched diet caused hyperphosphorylated tau accumulation in rabbits. It discusses tau-transgenic mice separately, but does not report that a cholesterol-enriched diet increased tau phosphorylation in those animals. Page numbers are not available in our copy. (LLM, conf=0.88)

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Authors
Ghribi, O.
Affiliations
University of North Dakota (US)
Corresponding author
Ghribi, Othman
ORCID
Ghribi, Othman
Venue
Journal of Alzheimer's Disease
Publisher
SAGE Publications
Published
2008-12-17
Volume
15
Issue
4
Pages
673-684
ISSN
  • 1387-2877 (ISSN-L)
  • 1875-8908
DOI
10.3233/jad-2008-15412
PMC
PMC2805037
OpenAlex
W1521675224
Cited by
68
References
1
Citations by year
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FWCI
3.17
Type
journal article
Language
en
Status
Retracted
Update notices
retraction (2024-03-01)
Open access
Locations
  • Journal of Alzheimer s Disease (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institute of Environmental Health Sciences (R01ES014826)
  • National Center for Research Resources (P20RR017699)
Topics
  • Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
  • Health Sciences › Medicine › Surgery › Cholesterol and Lipid Metabolism
  • Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
Keywords
Alzheimer's disease, cholesterol metabolism
MeSH terms
Alzheimer Disease, Animals, Brain, Brain Chemistry, Cholesterol, Hippocampus, Humans, Hydroxycholesterols, Organ Culture Techniques, Rabbits, Amyloid beta-Peptides, tau Proteins, Muscle, Skeletal, Myositis, Inclusion Body

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