HumMod - Large Scale Physiological Models in Modelica
Open accessAbstract
Modelica is being used more and more in industrial applications, but Modelica is still not used as much in biomedical applications.For a long time we have mostly been using Matlab/Simulink models, made by Mathworks, for the development of models of physiological systems.Recently, we have been using a simulation environment based on the Modelica language.In this language, we implemented a large scale model of interconnected physiological subsystems containing thousands of variables.Model is a richly hierarchically structured, easily modifiable, and "self-documenting".Modelica allows a much clearer than other simulation environments, to express the physiological nature of the modeled reality.
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Kofranek and colleagues noted that HumMod's model description is split into thousands of XML files and more than a thousand directories, and its structure and links are not easily identifiable.
“With respect to HumMod, Kofranek and colleagues have noted that “the model description has been divided into thousands of XML files and more than a thousand directories” and “the entire structure of the model and following links and references are not easily identifiable.”44”
From Testing Computer Models Predicting Human Responses to a High-Salt Diet: Implications for Understanding Mechanisms of Salt-Sensitive Hypertension (2018) · cites this paper as [44]
The QCP model's mathematical background is hidden in C++ source code.
“With respect to the QCP model, the mathematical background of the model is hidden in source code written in C++.44”
From Testing Computer Models Predicting Human Responses to a High-Salt Diet: Implications for Understanding Mechanisms of Salt-Sensitive Hypertension (2018) · cites this paper as [44]
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Self-citation
- Authors
- Kofranek, J., Matejak, M., & Privitzer, P.
- Affiliations
- Charles University (CZ)
- ORCID
- Matejak, Marek
- Venue
- Linköping Electronic Conference Proceedings
- Published
- 2011-06-30
- Volume
- 63
- Pages
- 713-724
- ISSN
- 1650-3686 (ISSN-L)
- OpenAlex
- W2004030468
- Semantic Scholar
- dc0bc04af7e5a9b20477c8b17932ec311393f135
- Cited by
- 14
- References
- 25
- Citations by year
- 2021: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2015: 4 · 2014: 5 · 2013: 1
- FWCI
- 1.65
- Type
- conference paper
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Linköping electronic conference proceedings (publishedVersion)
- Topics
- Physical Sciences › Computer Science › Computational Theory and Mathematics › Modeling and Simulation Systems
- Physical Sciences › Mathematics › Modeling and Simulation › Mathematical and Computational Methods
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gene Regulatory Network Analysis
- Keywords
- Modelica, physiological modeling, large-scale models, biomedical simulation, hierarchical model structure
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