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Cited by 297

The DOI matches its Crossref record; 162 of the 162 references it cites were found in a registry or an index.

Mechanisms of copper homeostasis in bacteria

Open access
Argüello, José M., Raimunda, Daniel, Padilla-Benavides, Teresita·2013·Frontiers in Cellular and Infection Microbiology

Abstract

Copper is an important micronutrient required as a redox co-factor in the catalytic centers of enzymes. However, free copper is a potential hazard because of its high chemical reactivity. Consequently, organisms exert a tight control on Cu(+) transport (entry-exit) and traffic through different compartments, ensuring the homeostasis required for cuproprotein synthesis and prevention of toxic effects. Recent studies based on biochemical, bioinformatics, and metalloproteomics approaches, reveal a highly regulated system of transcriptional regulators, soluble chaperones, membrane transporters, and target cuproproteins distributed in the various bacterial compartments. As a result, new questions have emerged regarding the diversity and apparent redundancies of these components, their irregular presence in different organisms, functional interactions, and resulting system architectures.

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Metadata

Authors
Argüello, J. M., Raimunda, D., & Padilla-Benavides, T.
Venue
Frontiers in Cellular and Infection Microbiology
Published
2013
Volume
3
Pages
73-73
ISSN
2235-2988 (ISSN-L)
OpenAlex
W1994677299
Cited by
297
References
162
FWCI
6.68
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Mechanisms of copper homeostasis in bacteria. https://app.cochat.ai/papers/10.3389/fcimb.2013.00073
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Argüello, J. M., Raimunda, D., & Padilla-Benavides, T. (2013). Mechanisms of copper homeostasis in bacteria. Frontiers in Cellular and Infection Microbiology. https://doi.org/10.3389/fcimb.2013.00073

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