The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Escherichia coli mechanisms of copper homeostasis in a changing environment
Open accessAbstract
Escherichia coli is equipped with multiple systems to ensure safe copper handling under varying environmental conditions. The Cu(I)-translocating P-type ATPase CopA, the central component in copper homeostasis, is responsible for removing excess Cu(I) from the cytoplasm. The multi-copper oxidase CueO and the multi-component copper transport system CusCFBA appear to safeguard the periplasmic space from copper-induced toxicity. Some strains of E. coli can survive in copper-rich environments that would normally overwhelm the chromosomally encoded copper homeostatic systems. Such strains possess additional plasmid-encoded genes that confer copper resistance. The pco determinant encodes genes that detoxify copper in the periplasm, although the mechanism is still unknown. Genes involved in copper homeostasis are regulated by MerR-like activators responsive to cytoplasmic Cu(I) or two-component systems sensing periplasmic Cu(I). Pathways of copper uptake and intracellular copper handling are still not identified in E. coli.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Multicopper oxidases and oxygenases
Solomon, E. I., Sundaram, U. M., & Machonkin, T. E. (1996) · Chemical Reviews · doi:10.1021/cr950046o · Cited by 3,664
The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake.
Askwith, C., Eide, D., Van Ho, A., Bernard, P. S., Li, L., Davis-Kaplan, S., Sipe, D. M., & Kaplan, J. (1994) · Cell · doi:10.1016/0092-8674(94)90346-8 · Cited by 670
The zntA gene of Escherichia coli encodes a Zn(II)-translocating P-type ATPase
Rensing, C., Mitra, B., & Rosen, B. P. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.26.14326 · Cited by 419
Self-citationNikaido, H., Basina, M., Nguyen, V., & Rosenberg, E. Y. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.17.4686-4692.1998 · Cited by 224
Laccase of Cryptococcus neoformans Is a Cell Wall-Associated Virulence Factor
Zhu, X., Gibbons, J., Garcia-Rivera, J., Casadevall, A., & Williamson, P. R. (2001) · Infection and Immunity · doi:10.1128/iai.69.9.5589-5596.2001 · Cited by 188
Multhaup, G., Strausak, D., Bissig, K.-D., & Solioz, M. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5757 · Cited by 75
Cited by
Pathogenesis of Helicobacter pylori Infection
Kusters, J. G., van Vliet, A. H. M., & Kuipers, E. J. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.00054-05 · Cited by 2,526
Metallic copper as an antimicrobial surface
Grass, G., Rensing, C., & Solioz, M. (2011) · Applied and Environmental Microbiology · doi:10.1128/aem.02766-10 · Cited by 1,640
Self-citationBacterial silver resistance: molecular biology and uses and misuses of silver compounds
Silver, S. (2003) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(03)00047-0 · Cited by 1,312
Metal homeostasis and resistance in bacteria
Chandrangsu, P., Rensing, C., & Helmann, J. D. (2017) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2017.15 · Cited by 812
Self-citationLaccases: structure, function, and potential application in water bioremediation
Arregui, L., Ayala, M., Gómez-Gil, X., Gutiérrez-Soto, G., Hernández-Luna, C. E., Herrera de los Santos, M., Levin, L., Rojo-Domínguez, A., Romero-Martínez, D., Saparrat, M. C. N., et al. (2019) · Microbial Cell Factories · doi:10.1186/s12934-019-1248-0 · Cited by 515
Metadata
- Authors
- Rensing, C., & Grass, G.
- Venue
- FEMS Microbiology Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-06
- Volume
- 27
- Issue
- 2-3
- Pages
- 197-213
- ISSN
- 0168-6445 (ISSN-L)
- 1574-6976
- OpenAlex
- W2161407287
- Cited by
- 736
- References
- 6
- FWCI
- 10.38
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Escherichia coli mechanisms of copper homeostasis in a changing environment. https://app.cochat.ai/papers/10.1016/s0168-6445(03)00049-4
- The paper
- Rensing, C., & Grass, G. (2003). Escherichia coli mechanisms of copper homeostasis in a changing environment. FEMS Microbiology Reviews. https://doi.org/10.1016/s0168-6445(03)00049-4
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
