High Levels of SIRT1 Expression as a Protective Mechanism Against Disease-Related Conditions
Cited by (171)
Items 101–171 of 171
- Bisphenol A instigates diminished sirtuin-1 mediated vascular complications in type 2 diabetes mellitusMohanraj Nehru, Prasanth Subramanian, Vinoth Kumar Ganesan, Rajiv Janardhanan, P. Venkataraman · 2023 · Journal of Nephropharmacology
- A Review of Proposed Mechanisms in Rheumatoid Arthritis and Therapeutic Strategies for the DiseaseRupali Mohite, Gaurav Doshi · 2023 · Endocrine Metabolic & Immune Disorders - Drug Targets
- Pharmacological and biochemical insights into lead-induced hepatotoxicity: Pathway interplay and the protective effects of arbutin via the oral and intraperitoneal routes in silico and in vivoAlzahraa Ahmed Elhemiely, Alshaymaa Darwish · 2024 · International Immunopharmacology
- Epigenetic Mechanisms of Cardioprotection: Focus is on Activation of SirtuinsК. А. Айтбаев, Ilkhom T. Murkamilov, Муркамилова Жамила Абдилалимовна, Indira Kudaibergenova, Furkat A. Yusupov · 2021 · The Russian Archives of Internal Medicine
- Effects of Fasting on Metabolic Hormones and Functions: A Narrative ReviewJulius E. Fink, Masami Tanaka, Shigeo Horie · 2024 · Juntendō Igaku/Juntendo igaku
- miR‑141 impairs mitochondrial function in cardiomyocytes subjected to hypoxia/reoxygenation by targeting Sirt1 and MFN2Hao Zhang, Yaqiao Wang, Kehan Wu, Runmin Liu, Hao Wang, Yongwei Yao, Peter R. Kvietys, Rui Xin Tao · 2022 · Experimental and Therapeutic Medicine
- Effect of trehalose on miR-132 and SIRT1 in the hippocampus of aged ratsBentolhoda Shafiei, Ali Afgar, Mohammad Hadi Nematollahi, Mohammad Shabani, Mahdieh Nazari‐Robati · 2023 · Neuroscience Letters
- Emerging Roles of HOTAIR LncRNA in the Pathogenesis and Prognosis of Cardiovascular DiseasesHabib Haybar, Hakimeh Hadi, Daryush Purrahman, Mohammad‐Reza Mahmoudian‐Sani, Najmaldin Saki · 2024 · Biomarkers in Medicine
- Preexisting multimorbidity predicts greater mortality risks related to long-term PM2.5 exposureZiqing Tang, Po‐Wen Ku, Yang Xia, Li‐Jung Chen, Yunquan Zhang · 2025 · Environmental Pollution
- Sirtuin-1 directly binds and deacetylates hepatic PCSK9 thereby promoting the inhibition of LDL receptor degradationVelagapudi, Srividya, Miranda, Melroy X, Adla, Priyanka, Kraler, Simon, Mohammed, Shafeeq A, Baki, Shekhar, Robert, Jerome, Rohrer, Lucia, Lee, Hwan, Jang, Hyun-Duk et al. · 2025 · Cardiovascular Research
- RNAa-mediated epigenetic attenuation of the cell senescence via locus specific induction of endogenous SIRT1Neda Mokhberian, Kazem Sharifi, Ehsan Soleymaninejadian, Mohamad Eftekhary, Seyed Mahmoud Hashemi, Shohreh Farhadi, Satomi Miwa, Hossein Ghanbarian · 2022 · Scientific Reports
- Can Sirtuin 1 Serve as a Therapeutic Target in Pulmonary Arterial Hypertension? A Comprehensive ReviewSandra Budziak, Monika Kloza, Anna Krzyżewska, Marta Baranowska‐Kuczko · 2025 · Molecules
- ACE2: Friend or Foe in Post-COVID-19 Neurodegeneration?Svetlana V. Kononova, Н. В. Бобкова, Р. А. Полтавцева, Sergey V. Leonov, Gennady T. Sukhikh · 2025 · International Journal of Molecular Sciences
- Genes involved in premature aging and their association with age-related diseases: A mini reviewGopikrishna Agraharam, Agnishwar Girigoswami, Pemula Gowtham, Koyeli Girigoswami · 2023 · Biomedical Research and Therapy
- Dysregulation of kidney structural polysaccharides and miRNA-21/SIRT1/NF-κB axis of injury and fibrosis in thioacetamide-induced nephrotoxicity is protected by resveratrolMohammed A. Alshehri, Ibrahim H. Tawhari, Faris Almasabi, Hind Awad Zafrah, Alia Saeed Albawardi, Nervana M. K. Bayoumy, Mohamed E. Abd Ellatif, Bahjat Al‐Ani, Norah Mohammed AlZamil, Samaa Samir Kamar · 2025 · Xenobiotica
- Calcitonin gene-related peptide (CGRP): A potential therapeutic target against sepsis and sepsis-associated multiple organ failureHarshita Singh, Manoj Naik, Manisha Suri, Mohd Hanifa, Amteshwar Singh Jaggi, Anjana Bali · 2025 · Biochemical Pharmacology
- Preliminary study on alleviation of heat-induced intestinal inflammation through compensatory effects of glucose oxidaseZ. Wang, D. -W. Zhang, Zhong-hai Xiao, C. -H. Qi, Jing Yuan, H. -X. Feng · 2021 · British Poultry Science
- In silico approach in the development of structural analogues of resveratrol with improved distribution in the central nervous systemDarko Mitrović, Nebojša Pavlović · 2024 · Kragujevac Journal of Science
- Understanding the Impact of the Sirtuin 1 (SIRT1) Gene on Age-related Macular Degeneration: A Comprehensive StudySaranya Velmurugan, Rashmi Pauline, Gurudeva Chandrashekar, Langeswaran Kulanthaivel, Gowtham Kumar Subbaraj · 2024 · Nigerian Postgraduate Medical Journal
- Association of SIRT1 (rs7069102) Gene polymorphism with premature myocardial infarction in young Egyptian patientsAli Mohamad Altaher, Amera Morad Foad, Wael Youssef, Ahmed Elsharawy Ahmed · 2024 · Egyptian Journal of Medical Human Genetics
- Comprehensive analysis of the prognostic, immunological, and diagnostic roles of SIRT1 in pan-cancer and its validation in KIRCQi Liu, Songxian Sun, Chunxiang Zhou, Houxi Xu · 2025 · Frontiers in Immunology
- RETRACTED ARTICLE: Extremely Active Nano-formulation of Resveratrol (XAR™) attenuates and reverses chemotherapy-induced damage in mice ovaries and testesSagar Chhabria, Vaishnavi Takle, Nripen S. Sharma, Prashant S. Kharkar, Kshama Pansare, Anish Tripathi, Ashish Tripathi, Deepa Bhartiya · 2022 · Journal of Ovarian Research · Retracted
- Activation of Sirtuin 1 by Ellagic Acid Ameliorates Cisplatin-Induced Apoptosis, Oxidative Stress and NephrotoxicityThikryat Neamatallah, Basma Ghazi Eid, Amina M. Bagher, Mohammed Z. Nasrullah, Soad Shaker Ali, Zuhair M. Mohammedsaleh, Nagla A. El‐Shitany · 2021 · Journal of Pharmaceutical Research International
- Sirtuin 1 mediates the pro-survival effects of vitamin D in angiotensin II-induced hypertrophy of H9c2 cardiomyoblastsAkram Astani, Abdulbaset Maroofi, Seyedhossein Hekmatimoghaddam, Mohammadtaghi Sarebanhassanabadi, Fatemeh Safari · 2024 · Molecular Biology Reports
- GADD45β inhibits hepatic lipogenesis through the AMPK/SREBP1 pathway via reducing the ubiquitination-mediated degradation of SIRT1Yuanyuan Xiao, Renjie Wang, Chaoyu Zhu, Qianqian Wang, Xinyi Wang, Wenjing Song, Shouxia Li, Fusong Jiang, 桂定坤, Youhua Xu et al. · 2025 · Scientific Reports
- Adaptation-Driven Evolution of Sirtuin 1 (SIRT1), a Key Regulator of Metabolism and Aging, in Marmot SpeciesNora Junker, Toni Ingolf Gossmann · 2021 · Frontiers in Ecology and Evolution
- Metadichol-Induced Differentiation of Pancreatic Ductal Cells (PANC-1) into Insulin-Producing CellsPalayakotai R. Raghavan · 2023 · Medical Research Archives
- The Antioxidant Properties and Cardiovascular, Antidiabetic, and Renal Effects of Trimetazidine Described in Research on Experimental ModelsAldahir Mero Rios, Juan Morán-Pinzón, Ciara Ordonez, Estela Guerrero De León · 2024 · Current Clinical Pharmacology
- Boosting Brain Clean-Up: Can Targeting UPS Genes Offer Neuroprotection?Ashi Mannan, Akhil Sharma, Thakur Gurjeet Singh · 2025 · Molecular Neurobiology
- Resveratrol, SIRT1, oxidative stress, and brain agingFiorella Sarubbo, Silvia Tejada, Susana Esteban, Manuel Jiménez‐García, David Moranta · 2020 · Elsevier eBooks
- Solanesol Mediated SIRT-1 Activation Prevents Neurobehavioral and Neurochemical Defects in Ouabain-Induced Experimental Model of Bipolar Disorder in RatsBidisha Rajkhowa, Sidharth Mehan, Pranshul Sethi, Sonalika Bhalla, Aradhana Prajapati, Sumit Kumar, Abdulrahman Alshammari, Metab Alharbi, Naif Alsuhaymi, Abdullah Alghamdi et al. · 2021 · Research Square
- Correlation between the Cognitive Status (SIRT1) and the Metabolic Function in Geriatric Patients Using the Indonesian Version of the Montreal Cognitive Assessment (MoCA-INA)Made Putra Semadhi, Dewi Muliaty, Eli Halimah, Jutti Levita · 2023 · Geriatrics
- Biochanin‑A as SIRT‑1 modulator in preventing statin‑associated diabetogenesis: An in vitro studyP.V. Anuranjana, Divya K.P, Fathima Beegum, Krupa Thankam George, Abhinav Kanwal, Rekha R. Shenoy, Krishnadas Nandakumar · 2025 · Biomedical Reports
- The hidden impact of intrauterine growth restriction in the pathogenesis of metabolic syndrome: Functional and structural alterations in rat visceral adipose tissueHanna Coppola, Khaled Al-Khalidi, Sandrine Gremlich, David Viertl, Umberto Siméoni, Jean-Baptiste Armengaud, Catherine Yzydorczyk · 2025 · The Journal of Nutritional Biochemistry
- Resveratrol Stabilizes Cytosolic ß-Catenin Through The Activation of The Thermogenic CascadeBengüsu Aydın, Nazlı Demirkıran, Sude Günaydın, Hakki Ogün Sercan · 2025 · Journal of Basic and Clinical Health Sciences
- Aloe Kanti, a natural anti-aging gel, modulates exogenous insult- and aging-induced aberrations in keratinocytes, dermal fibroblasts, melanocytes, and protects Caenorhabditis elegans from UVB photoagingAcharya Balkrishna, Vivek Gohel, Anushka Singh, Nishit Pathak, Meenu Tomer, Rishabh Dev, Anurag Varshney · 2025 · Fitoterapia
- Microglial Senescence in Neurodegenerative Diseases: Mechanisms and Therapeutic PerspectivesYixiao Liu, Zexuan Hu, Yitong Xiao, Xinyuan Han, Xiaorui Cheng, Tianyuan Ye · 2026 · ACS Chemical Neuroscience
- The effects of resveratrol on endothelial progenitor cells and apoptosis biomarkers in postmenopausal women with chronic coronary heart disease: a randomized controlled trialGustavo Henrique Ferreira Gonçalinho, Verônica Coelho, Sandra Maria Monteiro, Célia Maria Cássaro Strunz, Jorge Elias Kalil, Antônio de Pádua Mansur · 2026 · Frontiers in Nutrition
- Prevention of Aging and Improvement of Longevity and Life-Span in D-Galactose Induced Aging Rats After Treatment with the Biofield Energy Per Se and Biofield Treated Proprietary Test FormulationMahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Snehasis Jana · 2020 · Journal Of Aging Research And Healthcare
- SIRT1 Contributes as an Invasiveness Marker in Pituitary AdenomaDomantas Vaiciulis, Alvita Vilkevičiūtė, Greta Gedvilaitė, Brigita Glebauskienė, Loresa Kriaučiūnienė, Rasa Liutkevičienė · 2021 · Brain Sciences
- Association of Insulin receptor (INR) gene rs2252673 and Sirtuin1 rs7069102 polymorphisms with diabetic nephropathy in patients with type 2 diabetes mellitusMarwa Mohammed Ibrahim Mohammed Khalil, Heba E. Kasem, Shaimaa Elsayed Ramadan Genena · 2022 · Human Gene
- Intracellular p16INK4a profile as targeted protein in human endothelial progenitor cells after chronic asymmetric dimethylarginine exposureWiwit Nurwidyaningtyas, Djanggan Sargowo, Titin Andri Wihastuti, Ferry Sandra · 2022 · AIP conference proceedings
- Reviewed and updated Algorithm for Genetic Characterization of Syndromic Obesity PhenotypesRaquel Rodríguez‐López, Fátima Gimeno-Ferrer, David Albuquerque do Santos, Irene Ferrer‐Bolufer, Carola Guzmán Luján, Otilia Zomeño Alcalá, Amor García Banacloy, Virginia Ballesteros Cogollos, Carlos Sánchez Juan · 2022 · Current Genomics
- Solanesol Mediated SIRT-1 Signaling Activation Prevents Neurobehavioral and Neurochemical Defects in Ouabain-induced Experimental Model of Bipolar Disorder in RatsBidisha Rajkhowa, Sidharth Mehan · 2021 · Research Square
- Geroprotective effects of Aronia melanocarpa fruit extract on Drosophila melanogasterElena Yuryevna Platonova, Nadezhda Vladimirovna Zemskaya, Mikhail Vyacheslavovich Shaposhnikov, Denis Golubev, Daria V. Kukuman, Пакшина Наталья Ришатовна, Natalia S. Ulyasheva, Vasily V. Punegov, Sergey Aleksandrovich Patov, Alexey Moskalev · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Silent Information Regulator T1 in Aqueous Humor of Patients with Age-Related Macular DegenerationTatsuya Mimura, Hideharu Funatsu, Hidetaka Noma, Aki Kondo, Atsushi Mizota · 2021 · The Open Ophthalmology Journal
- Quantitative structure–activity relationship modeling reveals the minimal sequence requirement and amino acid preference of sirtuin-1’s deacetylation substrates in diabetes mellitusX. Shao, W. Kong, Y. Li, S. Zhang · 2022 · Journal of Bioinformatics and Computational Biology
- Papel da Sirtuina 1 na ativação e diferenciação das células T CD4>sup<+>/sup< em um modelo murino de obesidade e transplanteOmar Alberto Domínguez-Amorocho · 2022 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
- Immunofluorescent Distribution of SIRT1, SIRT2, SIRT6 Protein in the Skin of SKH1 Mouse after Ultraviolet B Irradiation for 10 WeeksCheol Kyu Oh, Hee Jung Kim, Min Sun Lee, Ji Ho Ryu, Myeung Ju Kim · 2022 · International Journal of Morphology
- The Multifaceted Roles of Ketogenic Diets in Neurology-Brain Cancers and Other Neurologic DiseasesAbdullah S. Binsaeedu, Moustafa Khalifa, Jocelyn L. Tan-Shalaby · 2023 · Recent Progress in Nutrition
- Long Noncoding RNAs and Epigenetic Regulation of Hyaluronan SynthesisIlaria Caon, Arianna Parnigoni, Manuela Viola, Evgenia G. Karousou, Paola Moretto, Alberto G. Passi, Davide Vigetti · 2023 · Biology of extracellular matrix
- Sirtuin1-Mediated Deacetylation of Hypothalamic TTF-1 Contributes to the Energy Deficiency ResponseDasol Kang, Hye Rim Yang, Dong Hee Kim, Kwang Kon Kim, Bora Jeong, Byong Seo Park, Jeong Woo Park, Jae Geun Kim, Byung Ju Lee · 2023 · International Journal of Molecular Sciences
- Late life vascular risk factors and their association with dementia and Alzheimer’s diseaseAbeer Abdelzaher Ibrahim, Hussain Younes Haji, Azza Mohamed Hassan · 2022 · Journal of Geriatric Medicine
- The Correlation of Plasma Sirt 1 Level and Frailty Degree in The Elderly OutpatientsFadhilah Hayati, Dedi Ardinata, Nuraiza Meutia, Ririe Fachrina Malisie, Muhammad Ichwan · 2024 · Journal of Endocrinology Tropical Medicine and Infectiouse Disease (JETROMI)
- Plasma Sirt-1 Level in Various Frailty Degree in Elderly Outpatients at Prof. Chairudin P. Lubis Hospital, MedanFadhilah Hayati, Dedi Ardinata, Nuraiza Meutia, Ririe Fachrina Malisie, Muhammad Ichwan · 2023 · International Journal of Ecophysiology
- Possibility of correction of cerebral blood flow disorders and central nervous system damage with citicoline in patients with coronary artery disease in combination with COVID-19В.З. Нетяженко, S.Ye. Mostovyi · 2024 · Infusion & Chemotherapy
- SIRT1 Controls Lipid Metabolism Under Physiological and Pathological Conditions: Implications in AtherosclerosisAnastasia Vladimirovna Poznyak, Л. В. Недосугова, Victoria Alexandrovna Khotina, Dmitry Felixovich Beloyartsev, Alexander Leonidovich Golovyuk, Vasily N. Sukhorukov, Vasily N. Sukhorukov, Alexandra Alexandrovna Melnichenko, Alexander Nikolaevich Orekhov · 2024 · OnLine Journal of Biological Sciences
- 37 kDa LRP::FLAG enhances telomerase activity and reduces ageing markers in vivoTyrone C. Otgaar, Martin Bernert, Gavin Morris, Pavan Baichan, Monique J. Bignoux, Boitelo T. Letsolo, Stefan F. T. Weiss, Eloise Ferreira · 2025 · Cellular and Molecular Life Sciences
- Genes as Genome Stabilizers in Pluripotent Stem CellsAsmita Karmakar, Allan Blessing Harison Raj Augustine, Rajkumar P. Thummer · 2025 · Advances in experimental medicine and biology
- Strontium regulating lipid metabolism of bovine hepatocytes via SIRT1/SREBPs pathwayFangyuan Zeng, Wenjuan Hu, Haichuan Xu, Xinxin Wang, Chenxu Zhao, Yazhou Wang, Jianguo Wang · 2025 · The Journal of Steroid Biochemistry and Molecular Biology
- Serum Levels of Nitric Oxide, SIRT1, MMP‐9 and Telomerase in Children With Cognitive Disengagement SyndromeSema Öznur Çeltik, Arif Önder, Berhan Akdağ, Halide S Akbas, Berke Öztürk, Mehmet Emre Gül, Mehmet Fatih Bütün, Hilal Yazıcı Kopuz, Özge Gizli Çoban, Aslı Sürer Adanır · 2025 · International Journal of Developmental Neuroscience
- Potential protective effects of Pistacia lentiscus L. var. latifolius coss extract against carbon tetrachloride-induced liver injury: Biochemical, histopathological, and computational insightsAmany Elsayed Ragab, Sherin Refat El Afify, Ghada M. Al‐Ashmawy, Mariam Ali Abo-Saif · 2025 · Fitoterapia
- Modulating Energy and Redox Homeostasis: A Review of Creatine, L-Carnitine, Melatonin, and Resveratrol in Neurodegenerative Diseases and Organic AcidemiasEllen C. S. B. Lima, Artur S. S. Maia, Priscila L. Silva, Enrico Tancredi, Marcela Simões Teruel, C. Ribeiro · 2025 · Nutraceuticals
- ЕФЕКТИ ПЕРСПЕКТИВНОГО АКТИВАТОРА СИРТУЇНУ-1 ПІРАБЕНТІНУ НА МОДЕЛІ ПРЕДІАБЕТУ У ЩУРІВN. S. Krasova, O. O. Plohotnichenko, Anastasia Morozyuk, N. V. Melnykivska, Жанна Лещенко, M. Y. Kudria, Вікторія Ліпсон · 2025 · PROBLEMS OF ENDOCRINE PATHOLOGY
- Discovery of Novel SIRT1 Activators Based on 2,3-Dihydro-1,5-benzodiazepines and a Study of Their Antidiabetic PropertiesVictoria V. Lipson, Alexander V. Kyrychenko, Fedir G. Yaremenko, V.M. Vakula, N. S. Krasova, Svitlana V. Kovalenko, Petro O. Borisko, Sergiy O. Zozulya, Alexander V. Borisov · 2026 · SynOpen
- SIRT1 in brain aging: molecular mechanisms and therapeutic potential of pharmacological and natural modulatorsEsraa M. Mosalam, Mahmoud S. Abdallah, Ahmed R. Gardouh, Eman Hamza, Mostafa M. Bahaa, Mahmoud Nazih, Reham Abdullah Al-Dhelaan, Noha Kamal · 2026 · Biogerontology
- Sirtuin inhibitors alter the food-by-temperature acclimation response to acute heat shock in Mytilus californianusMelissa May, R. Frank Fabela, Lars Tomanek · 2026 · Frontiers in Ecology and Evolution
- MicroRNAs in polyglutamine diseases: Mechanistic insights, circulating biomarkers, and emerging microRNA-based therapeutic strategiesYang Liu, Ying Cui, Miao Sun, Lin Gong, Kailiang Liu, Simiao Zhang, Xiaoping Tan, Shuyan Cong · 2026 · Neurobiology of Disease
- Endogenous Bioelectrical Modulation of Redox, Vascular Support, and Extracellular Matrix-Related Markers in Human Fibroblasts Following the REAC CO-IBZ ProtocolSara Cruciani, Vania Fontani, Arianna Rinaldi, Giuseppe Garroni, Diletta Serra, Salvatore Rinaldi, Margherita Maioli · 2026 · Biomedicines
- Targeting Specific Sirtuin Modulation: Emerging Therapeutic Strategies for Healthy Cognitive Ageing and Potential Implications for Alzheimer’s DiseaseCharlotte McDermott, Michael H. Cole, Madison A. Pearson, Pia C. Winberg, Francesca Fernandez · 2026 · Molecules
- Hyperglycemia-Induced Loss of Astrocytic Kir4.1 Is Associated with Increased DNMT1 Activity and Altered AMPK/SIRT1 SignalingJadier Colón‐Vázquez, Yanitza Hernandez-Santiago, Christian J. Malpica-Nieves, Nathaly M. Rosado-Rivera, Joshua J. Navedo-Jackson, Arelys A. Angueira-Laureano, Miguel P. Méndez-González, Yuriy Kucheryavykh, Misty J. Eaton, Serguei N. Skatchkov et al. · 2026 · Cells