The DOI matches its Crossref record; 118 of the 118 references it cites were found in a registry or an index.
The Role of the Pentose Phosphate Pathway in Diabetes and Cancer
Open accessAbstract
The pentose phosphate pathway (PPP) branches from glucose 6-phosphate (G6P), produces NADPH and ribose 5-phosphate (R5P), and shunts carbons back to the glycolytic or gluconeogenic pathway. The PPP has been demonstrated to be a major regulator for cellular reduction-oxidation (redox) homeostasis and biosynthesis. Enzymes in the PPP are reported to play important roles in many human diseases. In this review, we will discuss the role of the PPP in type 2 diabetes and cancer.
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Citations
Cites
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“Abnormally increased number and activity of ATMs as well as higher ratio of pro-inflammatory to anti-inflammatory macrophages are both hallmarks of obesityinduced inflammation (9).”
BackgroundReactive Oxygen Species in Metabolic and Inflammatory Signaling
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Cited by
Metabolism of tissue macrophages in homeostasis and pathology
Wculek, S. K., Dunphy, G., Heras-Murillo, I., Mastrangelo, A., & Sancho, D. (2022) · Cellular & Molecular Immunology · doi:10.1038/s41423-021-00791-9 · Cited by 501
Cytoplasmic and Mitochondrial NADPH-Coupled Redox Systems in the Regulation of Aging
Bradshaw, P. C. (2019) · Nutrients · doi:10.3390/nu11030504 · Cited by 178
The central moTOR of metabolism
Simcox, J., & Lamming, D. W. (2022) · Developmental Cell · doi:10.1016/j.devcel.2022.02.024 · Cited by 174
Itraconazole inhibits tumor growth via CEBPB‐mediated glycolysis in colorectal cancer
Zhang, Y., Li, L., Chu, F., Wu, H., Xiao, X., Ye, J., & Li, K. (2024) · Cancer Science · doi:10.1111/cas.16082 · Cited by 19
Metadata
- Authors
- Ge, T., Yang, J., Zhou, S., Wang, Y., Li, Y., & Tong, X.
- Venue
- Frontiers in Endocrinology
- Publisher
- Frontiers Media SA
- Published
- 2020-06-09
- Volume
- 11
- Pages
- 365-365
- ISSN
- 1664-2392 (ISSN-L)
- OpenAlex
- W3032976905
- Cited by
- 409
- References
- 118
- FWCI
- 15.96
- Type
- journal article
- Language
- en
- Open access
- gold
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- Ge, T., Yang, J., Zhou, S., Wang, Y., Li, Y., & Tong, X. (2020). The Role of the Pentose Phosphate Pathway in Diabetes and Cancer. Frontiers in Endocrinology. https://doi.org/10.3389/fendo.2020.00365
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
