Enhancement of the stability and cytotoxicity of berberine by liposomal nanocarriers for gastric cancer treatment and its application in gummy candy

Advances and Challenges of Liposome Assisted Drug Delivery

Sercombe, L., Veerati, T., Moheimani, F., Wu, S. Y., Sood, A. K., & Hua, S. (2015) · Frontiers in Pharmacology · doi:10.3389/fphar.2015.00286 · Cited by 2,672 · see citing works

Role of the Encapsulation in Bioavailability of Phenolic Compounds

Grgić, J., Šelo, G., Planinić, M., Tišma, M., & Bucić‐Kojić, A. (2020) · Antioxidants · doi:10.3390/antiox9100923 · Cited by 409 · see citing works

Berberine and barberry ( Berberis vulgaris ): A clinical review

Imenshahidi, M., & Hosseinzadeh, H. (2019) · Phytotherapy Research · doi:10.1002/ptr.6252 · Cited by 370 · see citing works

Indian Journal of Pharmaceutical Education and Research

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Spectrophotometric assays for total antioxidant capacity (TAC) in dog serum: an update

Rubio, C. P., Hernández‐Ruíz, J., Martı́nez-Subiela, S., Tvarijonaviciute, A., & Cerón, J. M. C. (2016) · BMC Veterinary Research · doi:10.1186/s12917-016-0792-7 · Cited by 312 · see citing works

Berberine, a plant alkaloid with lipid- and glucose-lowering properties: From in vitro evidence to clinical studies

Pirillo, A., & Catapano, A. L. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.09.032 · Cited by 308 · see citing works

Improvement in the stability of betanin by liposomal nanocarriers: Its application in gummy candy as a food model

Amjadi, S., Ghorbani, M., Hamishehkar, H., & Roufegarinejad, L. (2018) · Food Chemistry · doi:10.1016/j.foodchem.2018.02.114 · Cited by 214 · see citing works

Research progress on liposomes: Application in food, digestion behavior and absorption mechanism

Liu, W., Hou, Y., Jin, Y., Wang, Y., Xu, X., & Han, J. (2020) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2020.08.012 · Cited by 213 · see citing works

Tin(II)–quercetin complex: Synthesis, spectral characterisation and antioxidant activity

Dehghan, G., & Khoshkam, Z. (2011) · Food Chemistry · doi:10.1016/j.foodchem.2011.08.074 · Cited by 177 · see citing works

Pharmacological effects of berberine and its derivatives: a patent update

Jin, Y., Khadka, D. B., & Cho, W. (2015) · Expert Opinion on Therapeutic Patents · doi:10.1517/13543776.2016.1118060 · Cited by 173 · see citing works

Liposome encapsulated berberine treatment attenuates cardiac dysfunction after myocardial infarction

Allijn, I. E., Czarny, B., Wang, X., Chong, S. Y., Weiler, M., da Silva, A. E., Metselaar, J. M., Lam, C. S. P., Pastorin, G., de Kleijn, D. P. V., et al. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.12.042 · Cited by 156 · see citing works

Effect of composition, hydrogenation of phospholipids and lyophilization on the characteristics of eugenol-loaded liposomes prepared by ethanol injection method

Sebaaly, C., Greige‐Gerges, H., Stainmesse, S., Fessi, H., & Charcosset, C. (2016) · Food Bioscience · doi:10.1016/j.fbio.2016.04.005 · Cited by 134 · see citing works

Texture and structure of gelatin/pectin-based gummy confections

DeMars, L. L., & Ziegler, G. R. (2001) · Food Hydrocolloids · doi:10.1016/s0268-005x(01)00044-3 · Cited by 120 · see citing works

Berberine Inhibits Human Hepatoma Cell Invasion without Cytotoxicity in Healthy Hepatocytes

Liu, B., Wang, G., Yang, J., Pan, X., Yang, Z., & Zang, L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021416 · Cited by 110 · see citing works

Effects of high hydrostatic pressure on microstructure, texture, colour and biochemical changes of red abalone (Haliotis rufecens) during cold storage time

Briones-Labarca, V., Pérez‐Won, M., Zamarca, M., Aguilera-Radic, J. M., & Tabilo‐Munizaga, G. (2011) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2011.09.002 · Cited by 110 · see citing works

Benzydamine hydrochloride buccal bioadhesive gels designed for oral ulcers: Preparation, rheological, textural, mucoadhesive and release properties

Karavana, S. Y., Güneri, P., & Ertan, G. (2009) · Pharmaceutical Development and Technology · doi:10.3109/10837450902882351 · Cited by 102 · see citing works

Multiplex PCR to discriminate bovine, porcine, and fish DNA in gelatin and confectionery products

Sultana, S., Hossain, M. A. M., Zaidul, I. S. M., & Ali, M. E. (2018) · LWT · doi:10.1016/j.lwt.2018.02.019 · Cited by 76 · see citing works

Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases

Guo, H., Feng, C., Zhang, W., Luo, Z., Zhang, H., Zhang, T., Ma, C., Zhan, Y., Li, R. P., Wu, S., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09852-0 · Cited by 75 · see citing works

Gelatin-based anticancer drug delivery nanosystems: A mini review

Jiang, X., Du, Z. H., Zhang, X., Zaman, F., Song, Z., Guan, Y., Yu, T., & Huang, Y. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1158749 · Cited by 71 · see citing works

Berberine induces apoptosis by suppressing the arachidonic acid metabolic pathway in hepatocellular carcinoma

LI, J., LI, O., Kan, M., Zhang, M., Shao, D., Pan, Y., Zheng, H., Zhang, X., Chen, L., & Liu, S. (2015) · Molecular Medicine Reports · doi:10.3892/mmr.2015.3926 · Cited by 67 · see citing works

Encapsulation of berberine into liquid crystalline nanoparticles to enhance its solubility and anticancer activity in MCF7 human breast cancer cells

Loo, Y. S., Madheswaran, T., Rajendran, R., & Bose, R. J. (2020) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2020.101756 · Cited by 63 · see citing works

Natural Ingredients-Based Gummy Bear Composition Designed According to Texture Analysis and Sensory Evaluation In Vivo

Čižauskaitė, U., Jakubaitytė, G., Žitkevičius, V., & Kasparavičienė, G. (2019) · Molecules · doi:10.3390/molecules24071442 · Cited by 62 · see citing works

Potential cytotoxic and anti-metastatic effects of berberine on gynaecological cancers with drug-associated resistance

Mortazavi, H., Nikfar, B., Esmaeili, S., Rafieenia, F., Saburi, E., Chaichian, S., Gorji, M. A. H., & Momtazi‐Borojeni, A. A. (2019) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2019.111951 · Cited by 57 · see citing works

Nanoformulation and Evaluation of Oral Berberine-Loaded Liposomes

Duong, T. T., Isomäki, A., Paaver, U., Laidmäe, I., Tõnisoo, A., Yến, T. T. H., Kogermann, K., Raal, A., Heinämäki, J., & Pham, T.-M.-H. (2021) · Molecules · doi:10.3390/molecules26092591 · Cited by 57 · see citing works

Berberine inhibits the chemotherapy‐induced repopulation by suppressing the arachidonic acid metabolic pathway and phosphorylation of FAK in ovarian cancer

Zhao, Y., Cui, L., Pan, Y., Shao, D., Zheng, X., Zhang, F., Zhang, H., He, K., & Chen, L. (2017) · Cell Proliferation · doi:10.1111/cpr.12393 · Cited by 55 · see citing works

Berberine-Loaded Liposomes for the Treatment of Leishmania infantum-Infected BALB/c Mice

Calvo, A., Moreno, E., Larrea, E., Sanmartín, C., Irache, J. M., & Espuelas, S. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12090858 · Cited by 54 · see citing works

Dual-Targeted Nano-in-Nano Albumin Carriers Enhance the Efficacy of Combined Chemo/Herbal Therapy of Lung Cancer

Elgohary, M. M., Helmy, M. W., Mortada, S. M., & Elzoghby, A. O. (2018) · Nanomedicine · doi:10.2217/nnm-2018-0097 · Cited by 53 · see citing works

Clinical and pathological staging of gastric cancer: Current perspectives and implications

Zhu, Z., Gong, Y., & Xu, H. (2020) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2020.06.006 · Cited by 46 · see citing works

Hyaluronic acid-grafted PLGA nanoparticles for the sustained delivery of berberine chloride for an efficient suppression of Ehrlich ascites tumors

Bhatnagar, P., Kumari, M., Pahuja, R., Pant, A. B., Shukla, Y., Kumar, P., & Gupta, K. C. (2018) · Drug Delivery and Translational Research · doi:10.1007/s13346-018-0485-9 · Cited by 41 · see citing works

Physicochemical and Sensory Properties of Gummy Candies Enriched with Pineapple and Papaya Peel Powders

Romo-Zamarrón, K. F., Pérez-Cabrera, L. E., & Tecante, A. (2019) · Food and Nutrition Sciences · doi:10.4236/fns.2019.1011094 · Cited by 40 · see citing works

Synthesis and Nano-Sized Characterization of Bioactive Oregano Essential Oil Molecule-Loaded Small Unilamellar Nanoliposomes with Antifungal Potentialities

Aguilar-Pérez, K. M., Medina, D. I., Narayanan, J., Parra‐Saldívar, R., & Iqbal, H. M. N. (2021) · Molecules · doi:10.3390/molecules26102880 · Cited by 37 · see citing works

Polyphenols encapsulation – application of innovation technologies to improve stability of natural products

Tylkowski, B., & Tsibranska, I. (2016) · Physical Sciences Reviews · doi:10.1515/psr-2015-0005 · Cited by 33 · see citing works

Knockdown of RhoGDI2 represses human gastric cancer cell proliferation, invasion and drug resistance via the Rac1/Pak1/LIMK1 pathway

Zeng, Y., Ren, M., Li, Y., Liu, Y., Chen, C., Su, J., Su, B., Xia, H., Liu, F., Jiang, H., et al. (2020) · Cancer Letters · doi:10.1016/j.canlet.2020.07.013 · Cited by 28 · see citing works

Microfluidic fabrication of berberine-loaded nanoparticles for cancer treatment applications

Farahani, M., Moradikhah, F., Shabani, I., Karimi‐Soflou, R., & Seyedjafari, E. (2020) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2020.102134 · Cited by 27 · see citing works

Evaluation of Antioxidant Activity and Treatment of Eczema by Berberine Hydrochloride-Loaded Liposomes-in-Gel

Shen, S., Qu, X., Liu, Y., Wang, M., Zhou, H., & Xia, H. (2024) · Molecules · doi:10.3390/molecules29071566 · Cited by 25 · see citing works

The Sensory Evaluation and Mechanical Properties of Functional Gummy in the Malaysian MarketPreprint

Mahat, M. M., Sabere, A. S. M., Shafiee, S. A., Nawawi, M. A., Hamzah, H. H., Jamil, M. A. F. M., Roslan, N. C., Halim, M. I. A., & Safian, M. F. (2020) · Preprints.org · doi:10.20944/preprints202010.0213.v1 · Cited by 24 · see citing works

A H. pylori-independent miR-21 overexpression in gastric cancer patients

Dehdashtian, E., Tabatabaeian, H., Ghaedi, K., Talebi, A., & Adami, B. (2019) · Gene Reports · doi:10.1016/j.genrep.2019.100528 · Cited by 9 · see citing works

DNA binding ability and cytotoxicity, cell cycle arrest and apoptosis inducing properties of a benzochromene derivative against K562 human leukemia cells

Ahagh, M. H., Dehghan, G., Mahdavi, M., Feizi, M. A. H., Teimuri‐Mofrad, R., Payami, E., Mehdipour, M., & Rashtbari, S. (2021) · Nucleosides Nucleotides & Nucleic Acids · doi:10.1080/15257770.2021.1937644 · Cited by 3 · see citing works

In Vitro Evaluation of the Safety and Antineoplastic Effects in Gastrointestinal Tumors of Nanostructured Lipid Carriers Loaded with Berberine

Stefanova, D., Yordanov, Y., Bogdanova, R., Voycheva, C., Tzankov, B., Popova, T., Kondeva-Burdina, M., Tzankova, V., Toncheva-Moncheva, N., Tzankova, D., et al. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17030331 · Cited by 12 · see citing works

Demystifying the Potential of Polymeric Lipids as Substitute in Regenerative Applications: A Review

Mohite, P. B., Puri, A. V., Bharati, D., Munde, S. V., Malhan, A., Guleria, M., Datta, D., Pawar, A. R., Ranch, K. M., Singh, S. K., et al. (2025) · Polymers for Advanced Technologies · doi:10.1002/pat.70096 · Cited by 8 · see citing works

Nanotechnology-based drug delivery of natural products in cancer

Khan, S. A., Havelikar, U. A., & Godbole, M. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-40511-2.00010-3 · Cited by 2 · see citing works

Parenteral Berberine vs Cisplatin- Loaded Lipid Nanoparticles – Development, Characterisation, Comparative Safety Profiling and Cytotoxicity in Cholangiocarcinoma Cell Models

Manov, M., Stefanova, D., Tzankova, V., Tzankov, B., Lozano, E., Delgado-Calvo, K., Macias, R. I. R., Marin, J., Spassova, I., Kovacheva, D., et al. (2026) · Nanotechnology Science and Applications · doi:10.2147/nsa.s596038 · Cited by 2 · see citing works

PHYTOCHEMICAL CHARACTERIZATION AND EVALUATION OF ANTIOXIDANT, ANTIMICROBIAL, ANTI-INFLAMMATORY, AND CYTOTOXIC ACTIVITIES OF SEQUENTIAL EXTRACTS FROM RIPE BANANA (MUSA PARADISIACA L.) PEEL

Das, M., Koner, S., Dey, D., Roy, D. K., Roychowdhury, V., Khanra, R., & Palit, P. (2026) · International Journal of Drug Delivery Technology · doi:10.25258/ijddt.16.62s.146

Molecular Mechanisms Underlying the Anti-Inflammatory Effects of Fritillaria Alkaloids Targeting the NLRP3 Inflammasome

Wu, Z., Chen, Y., Fu, X., Li, Y., Lu, Y., & Sun, W. (2026) · Natural Product Communications · doi:10.1177/1934578x261425493

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

Maaz, M., Sultan, M. T., Israr, M., Khan, W. A., Tanveer, F., Hussain, M., Imran, M., Mujtaba, A., Memon, A. G., Atif, M., et al. (2026) · JSFA reports · doi:10.1002/jsf2.70079

Enhanced antioxidant and anti-inflammatory activities of BerbiQ compared with berberine and silymarin: integrated in vitro and in silico investigations

Bhairavi, V. A., Narayanan, V. A., Kuppadakath, S. A., Das, A., Amalraj, A., & Gopi, S. (2026) · In Silico Pharmacology · doi:10.1007/s40203-026-00733-1

Liposomal Delivery Systems for Berberine: Formulation Strategies, Pharmacokinetic Enhancement, and Therapeutic Applications

Suryawansh, D. R. S. K. D. (2026) · Zenodo (CERN European Organization for Nuclear Research) · doi:10.5281/zenodo.22124269

Enhancing Anticancer Potency of a 13-Substituted Berberine Derivative with Cationic Liposomes

Apiratikul, N., Sriklung, K., Dolsophon, K., Thamvapee, P., Watanapokasin, R. Y., Yingyongnarongkul, B., Niyomtham, N., Bremner, J. B., Watanavetch, P., & Samosorn, S. (2022) · Chemical and Pharmaceutical Bulletin · doi:10.1248/cpb.c21-01049 · Cited by 5 · see citing works

Optimizing manufacture of liposomal berberine with evaluation of its antihepatoma effects in a murine xenograft model

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Preparation, pharmacokinetics and tumour-suppressive activity of berberine liposomes

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Berberine Hydrochloride-loaded Liposomes Gel: Preparation, Characterization and Antioxidant Activity

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