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NK Cell-Based Immunotherapy in Colorectal Cancer

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IL-17 constrains natural killer cell activity by restraining IL-15–driven cell maturation via SOCS3

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A Flow Cytometry-Based Whole Blood Natural Killer Cell Cytotoxicity Assay Using Overnight Cytokine Activation

Kim, J.-H., Phan, M. T., Kweon, S., Yu, H., Park, J., Kim, K., Hwang, I., Han, S., Kwon, M., & Cho, D. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01851 · Cited by 42 · see citing works

Differentiation of natural killer cells from induced pluripotent stem cells under defined, serum- and feeder-free conditions

Lupo, K. B., Moon, J.-I., Chambers, A. M., & Matosevic, S. (2021) · Cytotherapy · doi:10.1016/j.jcyt.2021.05.001 · Cited by 40 · see citing works

Systemic Interleukins’ Profile in Early and Advanced Colorectal Cancer

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Interleukins (Cytokines) as Biomarkers in Colorectal Cancer: Progression, Detection, and Monitoring

Maryam, S., Krukiewicz, K., Haq, I. U., Khan, A. A., Yahya, G., & Cavalu, S. D. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12093127 · Cited by 38 · see citing works

Regulation of mTOR, Metabolic Fitness, and Effector Functions by Cytokines in Natural Killer Cells

Viel, S., Besson, L., Marotel, M., Walzer, T., & Marçais, A. (2017) · Cancers · doi:10.3390/cancers9100132 · Cited by 38 · see citing works

Circulating NKp46+Natural Killer cells have a potential regulatory property and predict distinct survival in Non-Small Cell Lung Cancer

Picard, E., Godet, Y., Laheurte, C., Dosset, M., Galaine, J., Beziaud, L., Loyon, R., Boullerot, L., Joseph, E. L. M., Spehner, L., et al. (2018) · OncoImmunology · doi:10.1080/2162402x.2018.1527498 · Cited by 35 · see citing works

Colorectal Cancer at the Crossroads: The Good, the Bad, and the Future of Platinum-Based Drugs

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Expression and function of immune ligand-receptor pairs in NK cells and cancer stem cells: therapeutic implications

Voutsadakis, I. A. (2018) · Cellular Oncology · doi:10.1007/s13402-018-0373-9 · Cited by 28 · see citing works

ADCC: the rock band led by therapeutic antibodies, tumor and immune cells

Vincken, R., Armendáriz-Martínez, U., & Ruiz-Sáenz, A. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1548292 · Cited by 26 · see citing works

Hematopoietic Cells Derived from Cancer Stem Cells Generated from Mouse Induced Pluripotent Stem Cells

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Cross-Talk Between Tumor Cells Undergoing Epithelial to Mesenchymal Transition and Natural Killer Cells in Tumor Microenvironment in Colorectal Cancer

Vuletić, A. M., Martinović, K. M., Miletić, N. T., Zoidakis, J., Castellvı́-Bel, S., & Cavic, M. R. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.750022 · Cited by 26 · see citing works

In Vitro Killing of Colorectal Carcinoma Cells by Autologous Activated NK Cells is Boosted by Anti-Epidermal Growth Factor Receptor-induced ADCC Regardless of RAS Mutation Status

Turin, I., Delfanti, S., Ferulli, F., Brugnatelli, S., Tanzi, M., Maestri, M., Cobianchi, L., Lisini, D., Luinetti, O., Paulli, M., et al. (2017) · Journal of Immunotherapy · doi:10.1097/cji.0000000000000205 · Cited by 25 · see citing works

Natural killer cells and tumor metastasis

Lee, H. H., Kang, H., & Cho, H. (2017) · Archives of Pharmacal Research · doi:10.1007/s12272-017-0951-9 · Cited by 24 · see citing works

Identification of Spatial Proteomic Signatures of Colon Tumor Metastasis

Levy, J., Zavras, J. P., Veziroglu, E. M., Nasir-Moin, M., Kolling, F., Christensen, B. C., Salas, L. A., Barney, R. E., Palisoul, S. M., Ren, B., et al. (2023) · American Journal Of Pathology · doi:10.1016/j.ajpath.2023.02.020 · Cited by 24 · see citing works

CAR T Cells Targeting Membrane-Bound Hsp70 on Tumor Cells Mimic Hsp70-Primed NK Cells

Dezfouli, A. B., Yazdi, M., Benmebarek, M.-R., Schwab, M., Michaelides, S., Micciché, A., Geerts, D., Stangl, S., Klapproth, S., Wagner, E., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.883694 · Cited by 23 · see citing works

Innate tumor killers in colorectal cancer

Zhong, F., Lin, Y., Jing, X., Ye, Y., Wang, S., & Shen, Z. (2021) · Cancer Letters · doi:10.1016/j.canlet.2021.12.022 · Cited by 22 · see citing works

Perioperative arginine prevents metastases by accelerating natural killer cell recovery after surgery

Angka, L., de Souza, C. T., Baxter, K. E., Khan, S., Market, M., Martel, A. B., Tai, L., Kennedy, M. A., Bell, J. C., & Auer, R. C. (2022) · Molecular Therapy · doi:10.1016/j.ymthe.2022.05.024 · Cited by 22 · see citing works

New avenues for melanoma immunotherapy: Natural Killer cells?

Cristiani, C. M., Garofalo, C., Passacatini, L. C., & Carbone, E. (2019) · Scandinavian Journal of Immunology · doi:10.1111/sji.12861 · Cited by 22 · see citing works

Restoring NK cells functionality via cytokine activation enhances cetuximab-mediated NK-cell ADCC: A promising therapeutic tool for HCC patients

Mahgoub, S., Abosalem, H., Emara, M. M., Kotb, N. S., Maged, A., & Soror, S. H. A. (2021) · Molecular Immunology · doi:10.1016/j.molimm.2021.07.008 · Cited by 21 · see citing works

Immunomodulatory molecules in colorectal cancer liver metastasis

Kong, W.-S., Li, J.-J., Deng, Y., Ju, H., & Xu, R. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.217113 · Cited by 21 · see citing works

LIR‐1 educates expanded human NK cells and defines a unique antitumor NK cell subset with potent antibody‐dependent cellular cytotoxicity

Leijonhufvud, C., Reger, R. N., Segerberg, F., Theorell, J., Schlums, H., Bryceson, Y. T., Childs, R. W., & Carlsten, M. (2021) · Clinical & Translational Immunology · doi:10.1002/cti2.1346 · Cited by 21 · see citing works

Immunotherapies catering to the unmet medical need of cold colorectal cancer

Yuan, J., Li, J., Gao, C., Jiang, C., Xiang, Z., & Wu, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1022190 · Cited by 21 · see citing works

Preconditioning human natural killer cells with chorionic villous mesenchymal stem cells stimulates their expression of inflammatory and anti-tumor molecules

Abumaree, M., Alshehri, N., Almotery, A., Subayyil, A. M. A., Bahattab, E., Abomaray, F., Khatlani, T., Kalionis, B., Jawdat, D. M., El-Muzaini, M. F., et al. (2019) · Stem Cell Research & Therapy · doi:10.1186/s13287-019-1153-9 · Cited by 19 · see citing works

HCT-116 colorectal cancer cells secrete chemokines which induce chemoattraction and intracellular calcium mobilization in NK92 cells

Elemam, N. M., Al‐Jaderi, Z., Hachim, M. Y., & Maghazachi, A. A. (2019) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-019-02319-7 · Cited by 19 · see citing works

Characterization of the interaction between human decidua parietalis mesenchymal stem/stromal cells and natural killer cells

Abumaree, M., Bahattab, E., Alsadoun, A., Aldosaimani, A., Abomaray, F., Khatlani, T., Kalionis, B., El-Muzaini, M. F., Alawad, A. O., & Alaskar, A. S. (2018) · Stem Cell Research & Therapy · doi:10.1186/s13287-018-0844-y · Cited by 19 · see citing works

DNA Methylation Signatures of Tumor-Associated Natural Killer Cells with Self-Functionalized Nanosensor Enable Colorectal Cancer Diagnosis

Ishwar, D., Venkatakrishnan, K., Tan, B., & Haldavnekar, R. (2023) · Nano Letters · doi:10.1021/acs.nanolett.2c04914 · Cited by 18 · see citing works

Role of the Main Non HLA-Specific Activating NK Receptors in Pancreatic, Colorectal and Gastric Tumors Surveillance

Ferretti, E., Carlomagno, S., Pesce, S., Muccio, L., Obino, V., Greppi, M., Solari, A., Setti, C., Marcenaro, E., Chiesa, M. D., et al. (2020) · Cancers · doi:10.3390/cancers12123705 · Cited by 16 · see citing works

High neutrophil to lymphocyte ratio and decreased CD69+NK cells represent a phenotype of high risk in early-stage breast cancer patients

Mandó, P., Rizzo, M., Roberti, M. P., Juliá, E. P., Pampena, M. B., de la Puente, C. P., Loza, C. M., Ponce, C., Nadal, J. C., Coló, F. A., et al. (2018) · OncoTargets and Therapy · doi:10.2147/ott.s160911 · Cited by 15 · see citing works

Mass Cytometry Reveals a Sustained Reduction in CD16+ Natural Killer Cells Following Chemotherapy in Colorectal Cancer Patients

Shinko, D., McGuire, H. M., Diakos, C. I., Pavlakis, N., Clarke, S. J., Byrne, S. N., & Charles, K. A. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02584 · Cited by 15 · see citing works

Sirtuin 6 is a negative regulator of the anti-tumor function of natural killer cells in murine inflammatory colorectal cancer

Xiao, F., Hu, B., Si, Z., Yang, H., & Xie, J. (2023) · Molecular Immunology · doi:10.1016/j.molimm.2023.04.011 · Cited by 14 · see citing works

Memory-like differentiation enhances NK cell responses against colorectal cancer

Marín, N. D., Becker‐Hapak, M., Song, W. M., Alayo, Q. A., Marsala, L. I., Sonnek, N. M., Berrien-Elliott, M. M., Foster, M., Foltz, J. A., Tran, J., et al. (2024) · OncoImmunology · doi:10.1080/2162402x.2024.2348254 · Cited by 14 · see citing works

KLRG1 expression induces functional exhaustion of NK cells in colorectal cancer patients

Xu, C., Cao, K., Ma, A., Zheng, M., Xu, Y., & Tang, L. (2025) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-025-04059-3 · Cited by 13 · see citing works

Genetic Variants Involved in the cGAS-STING Pathway Predict Outcome in Patients with Metastatic Colorectal Cancer: Data from FIRE-3 and TRIBE Trials

Wang, J., Xiao, Y., Loupakis, F., Stintzing, S., Yang, Y., Arai, H., Battaglin, F., Kawanishi, N. K., Jayachandran, P., Soni, S., et al. (2022) · European Journal of Cancer · doi:10.1016/j.ejca.2022.05.016 · Cited by 13 · see citing works

Next Generation Immuno-Oncology Strategies: Unleashing NK Cells Activity

Mendoza, A., Álvarez, M., Maria, A. D., Margolin, K. A., Melero, I., & Ascierto, M. L. (2022) · Cells · doi:10.3390/cells11193147 · Cited by 13 · see citing works

Harnessing NK Cells to Control Metastasis

Deng, X., & Terunuma, H. (2022) · Vaccines · doi:10.3390/vaccines10122018 · Cited by 13 · see citing works

Patient’s Natural Killer Cells in the Era of Targeted Therapies: Role for Tumor Killers

Messaoudene, M., Frazao, A., Gavlovsky, P.-J., Toubert, A., Dulphy, N., & Caignard, A. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00683 · Cited by 13 · see citing works

Dysregulation of systemic immunity in colorectal cancer and its clinical applications as biomarkers and therapeutics

Chang-qin, L., & Li, J. (2024) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2024.104543 · Cited by 12 · see citing works

Myricetin protects natural killer cells from arsenite induced DNA damage by attenuating oxidative stress and retaining poly(ADP-Ribose) polymerase 1 activity

Ma, H., Song, X., Huang, P. C., Zhang, W., Ling, X., Yang, X., Wu, W., Xu, H., & Wang, W. (2021) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2021.503337 · Cited by 12 · see citing works

IL15RA and SMAD3 Genetic Variants Predict Overall Survival in Metastatic Colorectal Cancer Patients Treated with FOLFIRI Therapy: A New Paradigm

Mattia, E. D., Polesel, J., Roncato, R., Labriet, A., Bignucolo, A., Gagno, S., Buonadonna, A., D'Andrea, M. R., Lévesque, É., Jonker, D. J., et al. (2021) · Cancers · doi:10.3390/cancers13071705 · Cited by 12 · see citing works

Identification of immune cell infiltration landscape for predicting prognosis of colorectal cancer

Wu, X., Li, J., Zhang, Y., Cheng, Y., Wu, Z., Zhan, W., & Deng, Y. (2022) · Gastroenterology report · doi:10.1093/gastro/goad014 · Cited by 12 · see citing works

Immune Profiling of Deficient Mismatch Repair Colorectal Cancer Tumor Microenvironment Reveals Different Levels of Immune System Activation

Giannini, R., Zucchelli, G., Giordano, M., Ugolini, C., Moretto, R., Ambryszewska, K. E., Leonardi, M., Sensi, E., Morano, F., Pietrantonio, F., et al. (2020) · Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2020.02.008 · Cited by 12 · see citing works

Modeling mesenchymal stromal cell support to hematopoiesis within a novel 3D artificial marrow organoid system

Schell, B., Zhao, L., M'Sibih, I., Kalogeraki, M., Kergaravat, C., Lereclus, E., Fenaux, P., Adès, L., Toubert, A., Espéli, M., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-07717-9 · Cited by 10 · see citing works

NK cells and the profile of inflammatory cytokines in the peripheral blood of patients with advanced carcinomas

Saito, L. M., Ortiz, R. C., Amôr, N. G., Lopes, N. M., Buzo, R. F., Garlet, G. P., & Rodini, C. O. (2023) · Cytokine · doi:10.1016/j.cyto.2023.156455 · Cited by 10 · see citing works

Peripheral White Blood Cell Subsets in Metastatic Colorectal Cancer Patients Treated with Cetuximab: The Potential Clinical Relevance

Matić, I. Z., Kolundžija, B., Damjanović, A., Spasić, J., Radosavljevic, D. Z., Crnogorac, M. Đ., Grozdanić, N., & Juranić, Z. D. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01886 · Cited by 10 · see citing works

Phenotypic and functional exhaustion of circulating CD3 + CD56 + NKT ‐like cells in colorectal cancer patients

Cao, K., Wang, X., Wang, H. ‐., Xu, C., Ma, A., Zhang, Y., Zheng, M., Xu, Y., & Tang, L. (2024) · The FASEB Journal · doi:10.1096/fj.202301743r · Cited by 9 · see citing works

Natural killer (NK) cells and their involvement in different types of cancer. Current status of clinical research

Zaharescu, I., Moldovan, A.-D., & Tănase, C. (2017) · Journal of Mind and Medical Sciences · doi:10.22543/7674.41.p3137 · Cited by 8 · see citing works

Sirtuin 2 up‐regulation suppresses the anti‐tumour activity of exhausted natural killer cells in mesenteric lymph nodes in murine colorectal carcinoma

Jiang, B., Ke, C., Zhou, H., Xia, T., Xie, X., & Xu, H. (2023) · Scandinavian Journal of Immunology · doi:10.1111/sji.13317 · Cited by 8 · see citing works

Changes in natural killer cell activity after surgery and predictors of its recovery–failure

Kim, E. Y., & Hong, T. H. (2021) · Journal of Surgical Oncology · doi:10.1002/jso.26636 · Cited by 6 · see citing works

The diversity of natural killer cell functional and phenotypic states in cancer

Rishabh, K., & Matosevic, S. (2025) · Cancer and Metastasis Reviews · doi:10.1007/s10555-025-10242-w · Cited by 5 · see citing works

Flow Cytometric Assessment of FcγRIIIa-V158F Polymorphisms and NK Cell Mediated ADCC Revealed Reduced NK Cell Functionality in Colorectal Cancer Patients

Schiele, P., Kolling, S., Rosnev, S., Junkuhn, C., Walter, A. L., von Einem, J. C., Stintzing, S., Schöning, W., Sauer, I. M., Modest, D. P., et al. (2024) · Cells · doi:10.3390/cells14010032 · Cited by 5 · see citing works

Monomethylarsonous acid: Induction of DNA damage and oxidative stress in mouse natural killer cells at environmentally-relevant concentrations

Xu, H., Wang, X., & Wang, W. (2018) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2018.05.017 · Cited by 5 · see citing works

Natural killer cell-based immunotherapies for colorectal cancer: Current strategies, challenges, and future perspectives

Zhang, X., Yu, Y., Li, J., Yan, Y., Jiang, S., Zhang, Y., Qin, F., Zhang, Y., Zhao, Y., Guo, L., et al. (2025) · World Journal of Gastroenterology · doi:10.3748/wjg.v31.i34.110051 · Cited by 4 · see citing works

Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer

Zhang, W., Yang, C., Lu, Y., Tang, C., Zhao, M., Wang, Z., Gao, J., Hu, S., & Chen, Z. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1532306 · Cited by 3 · see citing works

Evaluation of the associations between GDF-15, OPG, and IL-15 levels in CRC: preliminary results

Robotycka, J., Mielcarska, S., Dawidowicz, M., Kula, A., Ochman, B., Niebudek, T., Strzałkowska, B., Waniczek, D., & Świętochowska, E. (2022) · Medical Research Journal · doi:10.5603/mrj.a2022.0037 · Cited by 3 · see citing works

The role of natural killer cell activity as a milestone in oncologic outcome after curative resection of pancreatic adenocarcinoma

Kim, E. Y., Yoon, Y. C., & Hong, T. H. (2023) · Journal of Surgical Oncology · doi:10.1002/jso.27432 · Cited by 3 · see citing works

Human decidua basalis mesenchymal stem/stromal cells enhance anticancer properties of human natural killer cells, in vitro

Almutairi, A. S., Alshehri, N., Subayyil, A. M. A., Bahattab, E., Alshabibi, M. A., Abomaray, F., Basmaeil, Y. S., & Khatlani, T. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1435484 · Cited by 2 · see citing works

Engineering Bi-Specific CAR-NK Cells to Restore Antibody-Dependent Cellular Cytotoxicity in Solid Tumors

Chung, J. Y., Kim, J., Cha, D., Lee, H. J., Verhoeyen, E., An, H. J., & Park, J. E. (2026) · Cells · doi:10.3390/cells15040373 · Cited by 2 · see citing works

Zinc finger protein 217 contributes to natural killer cell dysfunction in murine colorectal cancer

Yu, Y., Yang, H., Wang, H., & Xiao, F. (2025) · Cellular Immunology · doi:10.1016/j.cellimm.2025.104971 · Cited by 2 · see citing works

Bistable dynamics of TAN-NK cells in tumor growth and control of radiotherapy-induced neutropenia in lung cancer treatment

Lee, D., Oh, S., Lawler, S. E., & Kim, Y. (2025) · Mathematical Biosciences & Engineering · doi:10.3934/mbe.2025028 · Cited by 2 · see citing works

The CD16A and CD16B mRNA level as potential immunological marker in colorectal cancer

Красногорова, Н. В., Novikov, D. V., Фомина, С. Г., Alyasova, A. V., Magomedov, M. A., Vv, N., & Karaulov, A. V. (2019) · Bulletin of Siberian Medicine · doi:10.20538/1682-0363-2019-1-220-227 · Cited by 2 · see citing works

Cytokine preactivation and ADCC: a potent strategy for enhancing human NK cell effector functions against 3D tumor models

Lopez-Pardo, A., Amarilla-Irusta, A., Iturbe-Larrondo, A., Juan, I. S., Sandá, V., Zenarruzabeitia, O., Ciccarelli, F. D., Borrego, F., & Amo, L. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1797290 · Cited by 1 · see citing works

Tissue Infiltrating Immune Cells and Endometrial Cancer Prognosis

Drakes, M. L., Drakes, M. L., Mehrotra, S., Potkul, R. K., Czerlanis, C. M., & Stiff, P. J. (2021) · Clinical Oncology and Research · doi:10.31487/j.cor.2021.04.01 · Cited by 1 · see citing works

Chemotherapy driven alterations in NK cell receptors and ligands in high grade serous ovarian cancer

Kumar, P., Ranmale, S., Mehta, S., Tongaonkar, H. B., Maniar, V., & Mania‐Pramanik, J. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1765987 · Cited by 1 · see citing works

Bridging aging and colorectal cancer: synergistic roles of inflammaging and immunosenescence

Zaongo, S. D., Yang, Q., Han, M., Xi, T., Luo, Z., Wang, X., Yang, J., & Ouyang, J. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1792954 · Cited by 1 · see citing works

Two-dimensional dynamic evaluation of natural killer cell-mediated lysis of adherent target cells

Frazao, A., Rethacker, L., & Caignard, A. (2019) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2019.07.033 · Cited by 1 · see citing works

Cataloging circulating CD3+CD56+ NKT-like cells through a series of stimulating (NKG2D and DNAM-1) and inhibitory (PD-1, TIGIT, and Tim-3) immune checkpoint receptors in women diagnosed with precancerous cervical lesions or invasive cervical carcinoma

Ibarra, F. S., Alejandre-González, A. G., Ortiz‐Lazareno, P. C., Bueno-Topete, M. R., Téllez‐Bañuelos, M. C., Haramati, J., & del Toro‐Arreola, S. (2024) · Immunology Letters · doi:10.1016/j.imlet.2024.106889 · Cited by 1 · see citing works

Natürliche Killerzellen, Adipositas & Tumorgenese

Spielmann, J., Bähr, I., Naujoks, W., Kielstein, H., & Quandt, D. (2019) · Adipositas - Ursachen Folgeerkrankungen Therapie · doi:10.1055/a-0801-4014

Hematological and immune disorders in colorectal cancer patients with liver metastases after radiofrequency ablation

Kuzmenko, О. V., Сорочан, П. П., & Балака, С. М. (2022) · Український радіологічний та онкологічний журнал · doi:10.46879/ukroj.3.2022.54-64

EVALUATION OF THE ACTIVITY OF PERIPHERAL BLOOD NATURAL KILLER CELLS IN HEALTHY SUBJECTS AND BREAST CANCER PATIENTS

Dieu, T. C., Phung, T. H., Nguyen, H. P., Hoang, T. K., Nguyễn, N. T., Nguyen, D. D., & Đỗ, K. Đ. (2023) · VietNam Military Medical Unisversity · doi:10.56535/jmpm.v48i5.321

Comprehensive Profiling of Immune Cell Populations and Cytokine Signatures in Colorectal Cancer PatientsPreprint

Huynh, C. D., Nguyen, P. M., Ngo, T. D., Nguyen, X., Nguyen, T. D., Mai, H. T., Le, H. T., Hoang, D. M., Le, L. K., Nguyen, Q. K., et al. (2025) · Preprints.org · doi:10.20944/preprints202501.0518.v1

The Influence of the Colorectal Cancer Immune Microenvironment on Resistance to Cetuximab: Mechanisms and Potential Therapeutic Strategies

叶, 唐. (2025) · Advances in Clinical Medicine · doi:10.12677/acm.2025.15123695

Etude phénotypique et fonctionnelle des cellules NK dans un contexte de cancer et d'inflammation

Picard, É. (2017) · doi:10.70675/43ce92f0z4ba9z4d80zbf69z0d61fe38a8c1

KLRG1 silencing increases the efficacy of CAR NK cell therapy against colon cancer via SHP-2/ZAP-70/NF-κB signal pathway

Chen, Y., Farooq, M. A., Hui, X., Huang, Y., Hu, Y., Xue, M., Ajmal, I., Ren, Y., Ji, Y., Wang, C., et al. (2026) · Journal of Translational Medicine · doi:10.1186/s12967-026-08267-y

Next-Generation Multi-Engager Complexes Linking Natural Killer Cells to Tumor Cells and Targeting the Proteolytic Checkpoint ADAM17

Dixon, K. J., & Walcheck, B. K. (2026) · Cells · doi:10.3390/cells15141269

Characterization and ex vivo functional properties of NKG2C+ NK cells with adaptive features in breast tumors

Bordignon, M. B., Viglietti, A. I. P., Sabatini, L., Nuñez, N. E., Amat, M., Fabiano, V. Y., Sánchez, S. N., Aebi, S., Brunacci, P. G., Flaibani, N., et al. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1995578

KLRG1 expression induces functional exhaustion of NK cells in colorectal cancer patients

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Altered phenotype in peripheral blood and tumor-associated NK cells from colorectal cancer patients

Rocca, Y., Roberti, M. P., Arriaga, J. M., Amat, M., Bruno, L. I., Pampena, M. B., Huertas, E., Loria, F. S., Pairola, A., Bianchini, M., et al. (2012) · Innate Immunity · doi:10.1177/1753425912453187 · Cited by 138 · see citing works

Las células NK como biomarcadores de respuesta a la terapia anti-EGFR en cáncer colorrectal metastásico: implicaciones clínicas y oportunidades terapéuticas

Navarrete‐Sirvent, C. (2026) · Universidad de Córdoba Insitutional Repository (Universidad de Córdoba)

Contribution of natural killer cells in innate immunity against colorectal cancer

Ghazvinian, Z., Abdolahi, S., Tokhanbigli, S., Tarzemani, S., Piccin, A., Zali, M. R., Verdi, J., & Baghaei, K. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2022.1077053 · Cited by 22 · see citing works

Changes in subset distribution and impaired function of circulating natural killer cells in patients with colorectal cancer

Zu, S., Lu, Y., Xing, R., Chen, X., & Zhang, L. (2024) · Scientific Reports · doi:10.1038/s41598-024-63103-x · Cited by 16 · see citing works