The DOI matches its Crossref record; 226 of the 226 references it cites were found in a registry or an index.
Immunotherapy: Reshape the Tumor Immune Microenvironment
Open accessAbstract
Tumor immune microenvironment (TIME) include tumor cells, immune cells, cytokines, etc. The interactions between these components, which are divided into anti-tumor and pro-tumor, determine the trend of anti-tumor immunity. Although the immune system can eliminate tumor through the cancer-immune cycle, tumors appear to eventually evade from immune surveillance by shaping an immunosuppressive microenvironment. Immunotherapy reshapes the TIME and restores the tumor killing ability of anti-tumor immune cells. Herein, we review the function of immune cells within the TIME and discuss the contribution of current mainstream immunotherapeutic approaches to remolding the TIME. Changes in the immune microenvironment in different forms under the intervention of immunotherapy can shed light on better combination treatment strategies.
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Metadata
- Authors
- LV, B., Wang, Y., Ma, D., Cheng, W., Liu, J., Yong, T., Chen, H., & Wang, C.
- Venue
- Frontiers in Immunology
- Publisher
- Frontiers Media SA
- Published
- 2022-07-06
- Volume
- 13
- Pages
- 844142-844142
- ISSN
- 1664-3224 (ISSN-L)
- OpenAlex
- W4286629873
- Cited by
- 482
- References
- 226
- FWCI
- 37.88
- Type
- journal article
- Language
- en
- Open access
- gold
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- LV, B., Wang, Y., Ma, D., Cheng, W., Liu, J., Yong, T., Chen, H., & Wang, C. (2022). Immunotherapy: Reshape the Tumor Immune Microenvironment. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2022.844142
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