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Cited by 15Gastroesophageal reflux and treatmentsEsophageal and GI PathologyEsophageal Cancer Research and Treatment

Endoscopic findings of gastro-esophageal reflux disease in elderly and younger age groups

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Adanir, Haydar, Baş, Bilge, Pakoz, Betul, Günay, Süleyman, Camyar, Hakan, Ustaoglu, Muge·2021·Frontiers in Medicine
DOI 10.3389/fmed.2021.606205PMC PMC8702798
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Abstract

Objective: To determine and compare the clinical features and endoscopic findings of gastro-esophageal reflux disease (GERD) in elderly and younger age groups. Materials and Methods: The clinical and endoscopic features were evaluated for all patients with GERD between January 2017 and September 2020. The criteria for inclusion were being aged over 65 and under 50 years and having an upper gastrointestinal endoscopy with reflux symptoms resistant to ppi theraphy. The exclusion criteria included prior surgery, age under 18 years, and pregnancy. The diagnosis of GERD was made according to the patients' symptoms. The SPSS 11.0 for Windows pocket program was used for statistical analysis. Results: Two hundred eighty-six patients aged over 65 years and 261 patients aged below 50 years were enrolled in this study. The mean age of the older group was 68.2 ± 4.5 years and the mean age of the young group was 38 ± 7.2 years. The male/female ratio was 5/3 and 2/1 in the young and older groups, respectively. The older patients had less severe and rare typical symptoms than the young patients. However, significantly more serious endoscopic findings were noted in the older patients compared with the younger patients. Conclusion: The older and young patients with GERD were predominantly male and typical reflux problems were less common in older patients with GERD. Older patients had more important endoscopic findings such as hernia, esophagitis, and cancer.

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  • Greater GERD duration causes increased erosive esophagitis, strictures, ulceration, and Barrett's esophagus.

    “Greater GERD duration causes increased erosive esophagitis, strictures, ulceration, and Barrett’s esophagus (Lin et al., 2019; Adanir et al., 2021).”

    From Thyroid disorders and gastrointestinal dysmotility: an old association (2024) · cites this paper as Adanir et al., 2021

    The Results (Table 3) show more severe esophagitis and more Barrett’s esophagus in older than younger GERD patients. The Introduction also describes both as GERD-related complications. But the paper compares age groups, not GERD duration, and does not establish that longer disease duration causes these outcomes; it does not report increased strictures or ulceration. (LLM, conf=0.87)

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Cited by

Sorted by citations

Authors
Adanir, H., Baş, B., Pakoz, B., Günay, S., Camyar, H., & Ustaoglu, M.
Affiliations
  • Antalya Eğitim ve Araştırma Hastanesi (TR)
  • Izmir Kâtip Çelebi University (TR)
Corresponding author
Baş, Bilge
ORCID
Venue
Frontiers in Medicine
Publisher
Frontiers Media SA
Published
2021-12-10
Volume
8
Pages
606205-606205
ISSN
2296-858X (ISSN-L)
DOI
10.3389/fmed.2021.606205
PMC
PMC8702798
OpenAlex
W4200138467
Cited by
15
References
0
Citations by year
2026: 2 · 2025: 6 · 2024: 3 · 2023: 3 · 2022: 1
FWCI
1.60
Type
journal article
Language
en
Open access
Licence
Locations
  • Frontiers in Medicine (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
  • Health Sciences › Medicine › Surgery › Esophageal and GI Pathology
  • Health Sciences › Medicine › Surgery › Esophageal Cancer Research and Treatment
Keywords
gastroesophageal reflux disease, elderly patients, age comparison, endoscopic findings, esophagitis, hiatal hernia, esophageal cancer, proton pump inhibitor therapy, reflux symptoms

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