Cited by 1,130Gastroesophageal reflux and treatmentsGastrointestinal motility and disordersEsophageal Cancer Research and Treatment

Updated Guidelines for the Diagnosis and Treatment of Gastroesophageal Reflux Disease

DeVault, Kenneth R., Castell, Donald O.·2005·The American Journal of Gastroenterology

Abstract

Guidelines for the diagnosis and treatment of gastroesophageal reflux disease (GERD) were published in 1995 and updated in 1999. These and other guidelines undergo periodic review. Advances continue to be made in the area of GERD, leading us to review and revise previous guideline statements. GERD is defined as symptoms or mucosal damage produced by the abnormal reflux of gastric contents into the esophagus. These guidelines were developed under the auspices of the American College of Gastroenterology and its Practice Parameters Committee, and approved by the Board of Trustees. Diagnostic guidelines address empiric therapy and the use of endoscopy, ambulatory reflux monitoring, and esophageal manometry in GERD. Treatment guidelines address the role of lifestyle changes, patient directed (OTC) therapy, acid suppression, promotility therapy, maintenance therapy, antireflux surgery, and endoscopic therapy in GERD. Finally, there is a discussion of the rare patient with refractory GERD and a list of areas in need of additional study.

Integrity signals

Registry

Crossref · 10.1111/j.1572-0241.2005.41217.x

Cites

192 of 192 references verified0 citation errors · 0 not checkable

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  • PPIs are the first-choice treatment for acid-related disorders such as bleeding, peptic ulcers, gastroesophageal reflux, erosive esophagitis (ERD) and certain dyspepsia subtypes.

    “PPIs are the first-choice treatment for acid-related disorders such as bleeding, peptic ulcers, gastroesophageal reflux, erosive esophagitis (ERD) and certain dyspepsia subtypes[2-5].”

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Authors
DeVault, K. R., & Castell, D. O.
Affiliations
  • Mayo Clinic in Florida (US)
  • Medical University of South Carolina (US)
Venue
The American Journal of Gastroenterology
Published
2005-01
Volume
100
Issue
1
Pages
190-200
ISSN
  • 0002-9270 (ISSN-L)
  • 1572-0241
OpenAlex
W2105606912
Cited by
1,130
References
192
Citations by year
2026: 1 · 2025: 6 · 2024: 16 · 2023: 13 · 2022: 15 · 2021: 25 · 2020: 23 · 2019: 21 · 2018: 37 · 2017: 29 · 2016: 42 · 2015: 44 · 2014: 44 · 2013: 50 · 2012: 65
FWCI
75.36
Type
journal article
Language
en
Open access
closed
Locations
  • The American Journal of Gastroenterology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Health Sciences › Medicine › Surgery › Esophageal Cancer Research and Treatment
Keywords
gastroesophageal reflux disease, diagnosis, treatment, empirical treatment, endoscopy, esophageal manometry, lifestyle modification, acid suppression, maintenance therapy, antireflux surgery, endoscopic treatment, refractory GERD
MeSH terms
Anti-Ulcer Agents, Endoscopy, Esophagus, Gastroesophageal Reflux, Humans, Life Style, Manometry, Self Care, Monitoring, Ambulatory

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