The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
One Juliet and four Romeos: VeA and its methyltransferases
Open accessAbstract
Fungal secondary metabolism has become an important research topic with great biomedical and biotechnological value. In the postgenomic era, understanding the diversity and the molecular control of secondary metabolites (SMs) are two challenging tasks addressed by the research community. Discovery of the LaeA methyltransferase 10 years ago opened up a new horizon on the control of SM research when it was found that expression of many SM gene clusters is controlled by LaeA. While the molecular function of LaeA remains an enigma, discovery of the velvet family proteins as interaction partners further extended the role of the LaeA beyond secondary metabolism. The heterotrimeric VelB-VeA-LaeA complex plays important roles in development, sporulation, secondary metabolism, and pathogenicity. Recently, three other methyltransferases have been found to associate with the velvet complex, the LaeA-like methyltransferase F and the methyltransferase heterodimers VipC-VapB. Interaction of VeA with at least four methyltransferase proteins indicates a molecular hub function for VeA that questions: Is there a VeA supercomplex or is VeA part of a highly dynamic cellular control network with many different partners?
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Cites
LaeA, a Regulator of Secondary Metabolism in Aspergillus spp
Bok, J. W., & Keller, N. P. (2004) · Eukaryotic Cell · doi:10.1128/ec.3.2.527-535.2004 · Cited by 902
Self-citationTranscriptional Regulation of Chemical Diversity in Aspergillus fumigatus by LaeA
Perrin, R. M., Fedorova, N. D., Bok, J. W., Cramer, R. A., Wortman, J. R., Kim, H. S., Nierman, W. C., & Keller, N. P. (2007) · PLoS Pathogens · doi:10.1371/journal.ppat.0030050 · Cited by 352
Self-citationLaeA, a Regulator of Morphogenetic Fungal Virulence Factors
Bok, J. W., Balajee, S. A., Marr, K. A., Andes, D., Nielsen, K. F., Frisvad, J. C., & Keller, N. P. (2005) · Eukaryotic Cell · doi:10.1128/ec.4.9.1574-1582.2005 · Cited by 283
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Cited by
Syafiuddin, A., Salmiati, Salim, M. R., Beng Hong Kueh, A., Hadibarata, T., & Nur, H. (2017) · Journal of the Chinese Chemical Society · doi:10.1002/jccs.201700067 · Cited by 415
Gu Liu, C., Green, S. I., Min, L., Clark, J. R., Salazar, K. C., Terwilliger, A. L., Kaplan, H. B., Trautner, B. W., Ramig, R. F., & Maresso, A. W. (2020) · mBio · doi:10.1128/mbio.01462-20 · Cited by 409
A review on biosurfactants: properties, applications and current developments
Markande, A. R., Patel, D., & Varjani, S. (2021) · Bioresource Technology · doi:10.1016/j.biortech.2021.124963 · Cited by 361
Understanding microbial community dynamics to improve optimal microbiome selection
Wright, R. J., Gibson, M. I., & Christie-Oleza, J. A. (2019) · Microbiome · doi:10.1186/s40168-019-0702-x · Cited by 341
Environmental sustainability: challenges and viable solutions
Arora, N. K., Fatima, T., Mishra, I., Verma, M., Mishra, J., & Mishra, V. (2018) · Environmental Sustainability · doi:10.1007/s42398-018-00038-w · Cited by 328
Metadata
- Authors
- Sarikaya-Bayram, Ã., Palmer, J. M., Keller, N., Braus, G. H., & Bayram, Ã.
- Venue
- Frontiers in Microbiology
- Publisher
- Frontiers Media SA
- Published
- 2015-01-20
- Volume
- 6
- Pages
- 1-1
- ISSN
- 1664-302X (ISSN-L)
- OpenAlex
- W2053098819
- Cited by
- 1,148
- References
- 3
- FWCI
- 90.10
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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