The Lactobacillus casei group: history and health related applications
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are some of the most widely researched and applied probiotic species of lactobacilli. The three species have been extensively studied, classified and reclassified due to their health promoting properties. Differentiation is often difficult by conventional phenotypic and genotypic methods and therefore new methods are being continually developed to distinguish the three closely related species. The group remain of interest as probiotics, and their use is widespread in industry. Much research has focused in recent years on their application for health promotion in treatment or prevention of a number of diseases and disorders. The LCG have the potential to be used prophylactically or therapeutically in diseases associated with a disturbance to the gut microbiota. The group have been extensively researched with regard to stress responses, which are crucial for their survival and therefore application as probiotics.
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The Lactobacillus casei group comprises closely related species L casei, L paracasei, and L rhamnosus, including L rhamnosus GG, and these species are difficult to differentiate.
“The Lactobacillus casei group comprises the closely related species L casei, L paracasei, and L rhamnosus, including L rhamnosus GG, and it is difficult to differentiate between these species (Hill 2018).”
From Probiotics for treating acute infectious diarrhoea (2020) · cites this paper as Hill 2018
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- Authors
- Hill, D., Sugrue, I., Tobin, C., Hill, C., Stanton, C., & Ross, R. P.
- Affiliations
- Teagasc - The Irish Agriculture and Food Development Authority (IE)
- University College Cork (IE)
- APC Microbiome Institute (IE)
- Corresponding author
- Ross, R. Paul
- Venue
- Frontiers in Microbiology
- Publisher
- Frontiers Media SA
- Published
- 2018-09-10
- Volume
- 9
- Pages
- 2107-2107
- ISSN
- 1664-302X (ISSN-L)
- PMC
- PMC6160870
- OpenAlex
- W2890556797
- Cited by
- 318
- References
- 123
- Citations by year
- 2026: 24 · 2025: 43 · 2024: 51 · 2023: 41 · 2022: 47 · 2021: 43 · 2020: 52 · 2019: 13 · 2018: 3 · 2015: 1
- FWCI
- 2.81
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Frontiers in Microbiology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Arrow@dit (Dublin Institute of Technology) (acceptedVersion)
- Cork Open Research Archive (University College Cork, Ireland) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- T-Stór (Teagasc) (submittedVersion, cc-by-nc-sa)
- Funders
- Science Foundation Ireland (SFI/12/RC/2273)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- Lactobacillus casei group, Lactobacillus casei, Lactobacillus paracasei, probiotics, species differentiation, gut microbiota, disease prevention, stress response, health promotion
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